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KLF14

Official Full Name

Kruppel-like factor 14
Overview

This gene encodes a member of the Kruppel-like family of transcription factors. The gene exhibits imprinted expression from the maternal allele in embryonic and extra-embryonic tissues. Expression of this gene is induced by TGF-beta, and the protein represses TGF-beta receptor II expression. The protein functions as part of a transcriptional co-repressor complex that also contains the transcriptional regulator SIN3A and histone deacetylase 2.
Synonyms

KLF14; Kruppel-like factor 14; Krueppel-like factor 14; BTEB5; BTE-binding protein 5; transcription factor BTEB5; basic transcription element-binding protein 5;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat

Source

E.coli
HEK293
HEK293T
Mammalian Cell

Tag

C
Myc
DDK
His
His (Fc)
Avi
Myc|DDK
N

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	KLF14-481H	Recombinant Human KLF14 Protein, MYC/DDK-tagged	HEK293	Myc/DDK		Inquiry
Human	KLF14-099H	Recombinant Human KLF14 Protein, MYC/DDK-tagged, C13 and N15-labeled	HEK293	C-Myc/DDK		Inquiry
Mouse	KLF14-8678M	Recombinant Mouse KLF14 Protein	Mammalian Cell	His		Inquiry
Mouse	Klf14-3701M	Recombinant Mouse Klf14 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Mouse	KLF14-4837M-B	Recombinant Mouse KLF14 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	KLF14-4837M	Recombinant Mouse KLF14 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	Klf14-6843R	Recombinant Rat Klf14 Protein (Full Length), N-His tagged	E.coli	N-His	Full Length	Inquiry

Involved Pathway
Protein Function
Interacting Protein
KLF14 Related Articles

KLF14 involved in several pathways and played different roles in them. We selected most pathways KLF14 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with KLF14 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

KLF14 has several biochemical functions, for example, DNA binding, chromatin binding, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KLF14 itself. We selected most functions KLF14 had, and list some proteins which have the same functions with KLF14. You can find most of the proteins on our site.

Function	Related Protein
DNA binding	ZBTB16;ZBTB39;ZNF184;GABPA;ZFP184;REPIN1;LEMD3;ZBTB8B;CERS5
chromatin binding	CBX4;TADA2A;ATAD2B;MLH3;FOXN4;CHD8;UXT;WDR82;NFATC3
metal ion binding	ZDHHC15A;DDHD2;CD209C;ZFP82;EXOG;PHF20B;ACVR2A;ZNF280B;GLIS2B
nucleic acid binding	GPATCH3;EAR1;ZIC2A;SF3B6;CNBPA;ZFP423;RBM12B2;ZBTB2A;Akap17b
transcriptional activator activity, RNA polymerase II transcription factor binding	NFE2L1;NKX2;KLF4;JUN;PITX1;FOXH1;CLOCK;NKX2-5;SOX10

KLF14 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KLF14 here. Most of them are supplied by our site. Hope this information will be useful for your research of KLF14.

Foxp3

Southwood, CM; Lipovich, L; et al. Tissue-Restricted Transcription from a Conserved Intragenic CpG Island in the Klf1 Gene in Mice. BIOLOGY OF REPRODUCTION 87:-(2012).

Klco, JM; Kulkarni, S; et al. Immunohistochemical Analysis of Monocytic Leukemias Usefulness of CD14 and Kruppel-like Factor 4, a Novel Monocyte Marker. AMERICAN JOURNAL OF CLINICAL PATHOLOGY 135:720-730(2011).