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KLRA1

  • Official Full Name

    killer cell lectin-like receptor, subfamily A, member2

  • Overview

    Ly-49A is a 44 kD member of the C-type lectin/Ly-49 family proteins. It is a type-II transmembrane, disulfide-linked homodimer with C-type lectin extracellular domains. Ly-49A is present on a subset of NK and NK-T cells. Ly-49A, like other members of this family, inhibits NK cell activation through the recognition and interaction of certain MHC class I haplotypes on potential target cells. The Ly-49A receptor recognizes H-2Ddand H-2Dk, triggering phosphorylation of the ITIM motif in the cytoplasmic domain and recruitment of SHP-1 and SHP-2.
  • Synonyms

    KLRA1; killer cell lectin-like receptor, subfamily A, member 1; T-cell surface glycoprotein YE1/48; ly-49a; lymphocyte antigen 49a; t lymphocyte antigen A1; class I MHC receptor KLRA22; natural killer cell receptor Ly49A; novel killer cell lectin-like receptor subfamily A protein; A1; Ly49a; Ly49v; Klra22; Ly49oCH29-493D4.3; Klra1; killer cell lectin-like receptor, subfamily A, member2;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Mus musculus (Mouse) RFL28181MF Recombinant Full Length Mouse T-Cell Surface Glycoprotein Ye1/48(Klra1) Protein, His-Tagged E.coli expression system His Full Length (1-262)

KLRA1 involved in several pathways and played different roles in them. We selected most pathways KLRA1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with KLRA1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

KLRA1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by KLRA1 itself. We selected most functions KLRA1 had, and list some proteins which have the same functions with KLRA1. You can find most of the proteins on our site.

Function Related Protein

KLRA1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KLRA1 here. Most of them are supplied by our site. Hope this information will be useful for your research of KLRA1.

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