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KMT2A

  • Recombinant Proteins
  • Human
  • Zebrafish
  • E. coli
  • E.coli
  • Insect Cell
  • Mammalian Cell
  • GST
  • His
  • SUMOpro
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human KMT2A-189H Active Recombinant Human KMT2A protein, GST-tagged Insect Cell GST 3738-end
Human KMT2A-128H Recombinant Human KMT2A Complex, His-tagged E.coli His
Human KMT2A-127H Recombinant Human KMT2A Protein, His-tagged E.coli His 1566-1784
Human KMT2A-54H Recombinant Human KMT2A, GST-tagged E.coli GST
Human KMT2A-001H Recombinant Human KMT2A Protein E.coli
Human KMT2A-002H Recombinant Human KMT2A Protein E. coli
Human KMT2A-006H Recombinant Human MLL1/WAR Complex Protein, SUMOpro-tagged E.coli SUMOpro
Human KMT2A-007H Recombinant Human MLL1/WARD Complex Protein, SUMOpro-tagged E.coli SUMOpro
Zebrafish KMT2A-6125Z Recombinant Zebrafish KMT2A Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • KMT2A Related Articles

KMT2A involved in several pathways and played different roles in them. We selected most pathways KMT2A participated on our site, such as Lysine degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with KMT2A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Lysine degradationSETD1B;ACAT1;SUV420H1;KMT2E;AGXT2L2;HADH;TMLHE;DLST;EHHADH

KMT2A has several biochemical functions, for example, DNA binding, histone methyltransferase activity (H3-K4 specific), histone-lysine N-methyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KMT2A itself. We selected most functions KMT2A had, and list some proteins which have the same functions with KMT2A. You can find most of the proteins on our site.

Function Related Protein
DNA bindingZFPM2;MAFGB;GTF2I;JRK;HOXA4A;PCGF6;ZFY2;GTF2IRD1;ARNTL1A
histone methyltransferase activity (H3-K4 specific)WDR82;KMT2A;WHSC1L1;SETMAR;KMT2E;MLL5;WBP7;SMYD1B;ASH1L
histone-lysine N-methyltransferase activitySETDB1;SUV39H1A;SMYD2B;SUV39H1B;PRDM2;SMYD2A;SETDB1B;DOT1L;SETD2
metal ion bindingZNF683;ZNF215;TRIM2A;OSR2;NRXN1A;AGMAT;DNMT3A;LNX2;OASL2
methyltransferase activityNSUN4;MGMT;FAM119B;PRDM15;FAM86C;METTL23;SMYD2A;MLL5;PRDM6
transferase activityDGKAA;AANAT;NAPRT;ILF2;PRKCBB;A3GALT2;ADKA;GKUP;KITB
zinc ion bindingZDHHC16B;TRIM72;UBR7;SIRT6;ADH1A;BRCA1;ADAMTS2;ZDHHC18B;PPARG

KMT2A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KMT2A here. Most of them are supplied by our site. Hope this information will be useful for your research of KMT2A.

Sutton, R; Shaw, PJ; et al. Persistent MRD before and after allogeneic BMT predicts relapse in children with acute lymphoblastic leukaemia. BRITISH JOURNAL OF HAEMATOLOGY 168:395-404(2015).
Kato, M; Hasegawa, D; et al. Allogeneic haematopoietic stem cell transplantation for infant acute lymphoblastic leukaemia with KMT2A (MLL) rearrangements: a retrospective study from the paediatric acute lymphoblastic leukaemia working group of the Japan Society for Haematopoietic Cell Transplantation. BRITISH JOURNAL OF HAEMATOLOGY 168:564-570(2015).
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