kmt2a
Share
  • Official Full Name
  • Synonyms
Cat.#:KMT2A-127HTag:His
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human KMT2A Protein, His-tagged
+Inquiry
Cat.#:KMT2A-128HTag:His
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human KMT2A Complex, His-tagged
+Inquiry
Cat.#:KMT2A-189HTag:GST
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human KMT2A protein, GST-tagged, Active
+Inquiry
Cat.#:KMT2A-54HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human KMT2A, GST-tagged
+Inquiry
Cat.#:KMT2A-6125ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish KMT2A
+Inquiry

Involved Pathway

KMT2A involved in several pathways and played different roles in them. We selected most pathways KMT2A participated on our site, such as Lysine degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with KMT2A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Lysine degradation
SUV39H2; CAMKMT; ALDH2.1; SETDB1; KMT2A; SUV420H2; GLT25D1; EHMT1A; ALDH2; C2orf34

Protein Function

KMT2A has several biochemical functions, for example, DNA binding, histone methyltransferase activity (H3-K4 specific), histone-lysine N-methyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KMT2A itself. We selected most functions KMT2A had, and list some proteins which have the same functions with KMT2A. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein NFE2L2A; ARHGEF38; ZFP668; ARHGAP35; TCEB3; ZNF326; JARID2B; KIF22; PRRX1A; TIGD2
Function histone methyltransferase activity (H3-K4 specific)
Related Protein SMYD1B; KMT2E; MLL1; WHSC1L1; WBP7; MLL5; SETMAR; KMT2A; WDR82; ASH1L
Function histone-lysine N-methyltransferase activity
Related Protein MLL5; EZH1; EZH2; SUV39H1B; SETD8A; SMYD1; SETD1B; KMT2A; WHSC1L1; SETD7
Function metal ion binding
Related Protein ZNF143B; ANTXR2A; FHL3B; ZFP583; RFPL4; CMTM2A; GALNT14; LNPA; VDRA; RNF216
Function methyltransferase activity
Related Protein NSUN5B; TRMT13; EHMT1A; C9orf114; FAM119B; ASMT2; SETD1B; COMTA; METTL21A; SETD8A
Function transferase activity
Related Protein DCKL1B; KAT7B; STK38A; EK1; PKM; B3GALT6; C1GALT1B; SULT3ST2; ERBB3A; SBK1
Function zinc ion binding
Related Protein ZDHHC4; ZKSCAN5; ADAMTSL3; RAG2; RNF141; ZNRD1; LHX1B; WBP7; APEX2; TRAIP

KMT2A Related Articles

Sutton, R; Shaw, PJ; et al. Persistent MRD before and after allogeneic BMT predicts relapse in children with acute lymphoblastic leukaemia. BRITISH JOURNAL OF HAEMATOLOGY 168:395-404(2015).
Kato, M; Hasegawa, D; et al. Allogeneic haematopoietic stem cell transplantation for infant acute lymphoblastic leukaemia with KMT2A (MLL) rearrangements: a retrospective study from the paediatric acute lymphoblastic leukaemia working group of the Japan Society for Haematopoietic Cell Transplantation. BRITISH JOURNAL OF HAEMATOLOGY 168:564-570(2015).