kmt2a
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  • Official Full Name
  • Synonyms
Cat.#:KMT2A-127HTag:His
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human KMT2A Protein, His-tagged
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Cat.#:KMT2A-128HTag:His
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human KMT2A Complex, His-tagged
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Cat.#:KMT2A-189HTag:GST
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human KMT2A protein, GST-tagged, Active
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Cat.#:KMT2A-54HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human KMT2A, GST-tagged
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Cat.#:KMT2A-6125ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish KMT2A
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Involved Pathway

KMT2A involved in several pathways and played different roles in them. We selected most pathways KMT2A participated on our site, such as Lysine degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with KMT2A were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Lysine degradation
GCDHB; SETD8; SETD8A; COLGALT2; ALDH1B1; ACAT2; ALDH2.1; SETD1BA; SETDB1; BBOX1

Protein Function

KMT2A has several biochemical functions, for example, DNA binding, histone methyltransferase activity (H3-K4 specific), histone-lysine N-methyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KMT2A itself. We selected most functions KMT2A had, and list some proteins which have the same functions with KMT2A. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein SIX7; POU5F3; SUPT3H; SCMH1; ZNF280D; LUC7L3; UNCX; ALS2CR8; HIST2H2BE; TTF2
Function histone methyltransferase activity (H3-K4 specific)
Related Protein SETMAR; WHSC1L1; MLL5; SETD3; KMT2E; ASH1L; SMYD1B; WDR82; KMT2A; MLL1
Function histone-lysine N-methyltransferase activity
Related Protein EHMT1A; SETD8A; PRDM9; EHMT1; SMYD2B; SETD8B; DOT1L; WBP7; EHMT2; PRDM2
Function metal ion binding
Related Protein KSR2; SLX1B; ZNF239; ZFP346; PPM1AA; ADAP1; DDHD2; ZDHHC18; USP4; RPL37A
Function methyltransferase activity
Related Protein FBLL1; PRDM9; PRDM1; SUV39H1B; MLL5; METTL10; METTL6; DNMT3AB; DNMT4; PCMT
Function transferase activity
Related Protein HS3ST3B1B; TOMT; GTDC2; POLN; POMGNT2; UGT2B6; DCKL1B; UGT1A2; ALG3; SAT2A
Function zinc ion binding
Related Protein SRSF7B; PTPN1; SETDB2; CXXC1; PPARD; ZNF385B; ATXN7L3; ZGLP1; MT1G; XRN2

KMT2A Related Articles

Sutton, R; Shaw, PJ; et al. Persistent MRD before and after allogeneic BMT predicts relapse in children with acute lymphoblastic leukaemia. BRITISH JOURNAL OF HAEMATOLOGY 168:395-404(2015).
Kato, M; Hasegawa, D; et al. Allogeneic haematopoietic stem cell transplantation for infant acute lymphoblastic leukaemia with KMT2A (MLL) rearrangements: a retrospective study from the paediatric acute lymphoblastic leukaemia working group of the Japan Society for Haematopoietic Cell Transplantation. BRITISH JOURNAL OF HAEMATOLOGY 168:564-570(2015).