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KCNJ15

  • Official Full Name

    potassium inwardly-rectifying channel, subfamily J, member 15

  • Overview

    Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Three transcript variants encoding the same protein have been found for this gene.
  • Synonyms

    KCNJ15; potassium inwardly-rectifying channel, subfamily J, member 15; ATP-sensitive inward rectifier potassium channel 15; IRKK; Kir1.3; Kir4.2; inwardly rectifying subfamily J member 15; ATP sensitive inward rectifier potassium channel 15; Inward rectifier K(+) channel Kir1.3; Inward rectifier K(+) channel Kir4.2; Inward rectifier K+ channel KIR4.2; IRK15_HUMAN; KCNJ 14; KCNJ 15; KCNJ14; MGC13584; Potassium channel; Potassium channel inwardly rectifying subfamily J member 15; Potassium inwardly rectifying channel J15; Potassium inwardly rectifying channel subfamily J member 15; OTTHUMP00000115737; OTTHUMP00000115738; OTTHUMP00000115740; OTTHUMP00000115742; OTTHUMP00000115743; OTTHUMP00000115746; inward rectifier;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Cavia porcellus (Guinea pig)
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • E.coli expression system
  • E.Coli or Yeast
  • HEK293
  • Mammalian Cell
  • Wheat Germ
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human KCNJ15-28454TH Recombinant Human KCNJ15 Wheat Germ N/A 66 amino acids
Mouse Kcnj15-3759M Recombinant Mouse Kcnj15, His-tagged E.Coli or Yeast His 375
Mouse KCNJ15-8515M Recombinant Mouse KCNJ15 Protein Mammalian Cell His
Mouse KCNJ15-4738M-B Recombinant Mouse KCNJ15 Protein Pre-coupled Magnetic Beads HEK293
Mouse KCNJ15-4738M Recombinant Mouse KCNJ15 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat KCNJ15-3199R Recombinant Rat KCNJ15 Protein Mammalian Cell His
Rat KCNJ15-2855R-B Recombinant Rat KCNJ15 Protein Pre-coupled Magnetic Beads HEK293
Rat KCNJ15-2855R Recombinant Rat KCNJ15 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cavia porcellus (Guinea pig) RFL28559CF Recombinant Full Length Guinea Pig Atp-Sensitive Inward Rectifier Potassium Channel 15(Kcnj15) Protein, His-Tagged E.coli expression system His Full Length (1-375)
Homo sapiens (Human) RFL14005HF Recombinant Full Length Human Atp-Sensitive Inward Rectifier Potassium Channel 15(Kcnj15) Protein, His-Tagged E.coli expression system His Full Length (1-375)
Mus musculus (Mouse) RFL1695MF Recombinant Full Length Mouse Atp-Sensitive Inward Rectifier Potassium Channel 15(Kcnj15) Protein, His-Tagged E.coli expression system His Full Length (1-375)
Rattus norvegicus (Rat) RFL11648RF Recombinant Full Length Rat Atp-Sensitive Inward Rectifier Potassium Channel 15(Kcnj15) Protein, His-Tagged E.coli expression system His Full Length (1-405)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • KCNJ15 Related Articles

KCNJ15 involved in several pathways and played different roles in them. We selected most pathways KCNJ15 participated on our site, such as Activation of G protein gated Potassium channels, Activation of GABAB receptors, G protein gated Potassium channels, which may be useful for your reference. Also, other proteins which involved in the same pathway with KCNJ15 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Activation of G protein gated Potassium channelsGNB3A;KCNJ15;KCNJ12;KCNJ10;KCNJ2;GNGT2B;GNGT2A;KCNJ2A;KCNJ4
Activation of GABAB receptorsKCNJ2A;KCNJ9;GNGT2A;ADCY3;GNGT2B;KCNJ4;KCNJ3;KCNJ2;KCNJ15
G protein gated Potassium channelsGNB3A;KCNJ4;GNGT2B;KCNJ15;KCNJ5;KCNJ2A;GNGT2A;KCNJ6;KCNJ10
GABA B receptor activationKCNJ4;KCNJ10;KCNJ12;KCNJ9;KCNJ2A;KCNJ2;KCNJ5;KCNJ6;GNB3A
GABA receptor activationKCNJ9;KCNJ10;GNGT2A;ARHGEF9;KCNJ15;GABRR2A;GNGT2B;GNB3A;KCNJ2A
Gastric acid secretionGNAI1;CALM4;Slc4a2;PRKCB;MYLK;KCNK2;KCNJ10;GNAQ;ATP1B2
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunitsGNGT2B;KCNJ4;KCNJ15;KCNJ12;KCNJ10;GNGT2A;KCNJ2A
Inwardly rectifying K+ channelsKCNJ1A.6;KCNJ1B;KCNJ14;KCNJ1A.1;KCNJ1A.5;KCNJ1;KCNJ1A.4;GNGT2B;KCNJ10

KCNJ15 has several biochemical functions, for example, inward rectifier potassium channel activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KCNJ15 itself. We selected most functions KCNJ15 had, and list some proteins which have the same functions with KCNJ15. You can find most of the proteins on our site.

Function Related Protein
inward rectifier potassium channel activityKCNJ1A.1;KCNJ18;KCNJ4;KCNJ2A;KCNQ5;KCNJ1A.5;KCNJ2;KCNJ8;KCNJ1B
protein bindingEIF3J;PSMB3;KAT6B;CALU;PAGE1;RAB6B;VPS25;GNAI3;KIF3B

KCNJ15 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KCNJ15 here. Most of them are supplied by our site. Hope this information will be useful for your research of KCNJ15.

Il16; Inadl

Qin, LJ; Lv, Y; et al. Meta-analysis of association of common variants in the KCNJ11-ABCC8 region with type 2 diabetes. GENETICS AND MOLECULAR RESEARCH 12:2990-3002(2013).
Okamoto, K; Iwasaki, N; et al. Inhibition of Glucose-Stimulated Insulin Secretion by KCNJ15, a Newly Identified Susceptibility Gene for Type 2 Diabetes. DIABETES 61:1734-1741(2012).
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