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KHSRP

  • Official Full Name

    KH-type splicing regulatory protein

  • Overview

    The KHSRP gene encodes a multifunctional RNA-binding protein implicated in a variety of cellular processes, including;transcription, alternative pre-mRNA splicing, and mRNA localization (Min et al., 1997 (PubMed 9136930); Gherzi et al.,;2004 (PubMed 15175153)).
  • Synonyms

    KHSRP; KH-type splicing regulatory protein; far upstream element-binding protein 2; FBP2; FUBP2; FUSE binding protein 2; KSRP; p75; FUSE-binding protein 2; KH type-splicing regulatory protein; MGC99676;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mamanlian cells
  • Mammalian Cell
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • MYC
  • Myc|DDK
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human KHSRP-892H Recombinant Human KHSRP protein, MYC/DDK-tagged HEK293 Myc/DDK
Human KHSRP-895H Recombinant Human KHSRP protein, MYC/DDK-tagged HEK293 Myc/DDK
Human KHSRP-893H Recombinant Human KHSRP protein, GST-tagged Wheat Germ GST
Human KHSRP-894H Recombinant Human KHSRP protein, His-tagged E.coli His 2-711 aa
Human KHSRP-1780HFL Recombinant Full Length Human KHSRP protein, Flag-tagged Mamanlian cells Flag
Human KHSRP-1289H Recombinant Human KHSRP Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse KHSRP-8615M Recombinant Mouse KHSRP Protein Mammalian Cell His
Mouse KHSRP-4802M Recombinant Mouse KHSRP Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Khsrp-1264M Recombinant Mouse Khsrp Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse KHSRP-4802M-B Recombinant Mouse KHSRP Protein Pre-coupled Magnetic Beads HEK293
Rat KHSRP-3247R Recombinant Rat KHSRP Protein Mammalian Cell His
Rat KHSRP-2903R Recombinant Rat KHSRP Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat KHSRP-2903R-B Recombinant Rat KHSRP Protein Pre-coupled Magnetic Beads HEK293
Zebrafish KHSRP-5552Z Recombinant Zebrafish KHSRP Mammalian Cell His
Chicken KHSRP-5850C Recombinant Chicken KHSRP Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • KHSRP Related Articles

KHSRP involved in several pathways and played different roles in them. We selected most pathways KHSRP participated on our site, such as Gene Expression, KSRP (KHSRP) binds and destabilizes mRNA, Regulation of mRNA stability by proteins that bind AU-rich elements, which may be useful for your reference. Also, other proteins which involved in the same pathway with KHSRP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Gene ExpressionZNF317;ZNF625;RBB4L;CCNC;TRMT1;MBD3B;ZNF500;ZNF566;ZNF70
KSRP (KHSRP) binds and destabilizes mRNAEXOSC8;DCP2;KHSRP
Regulation of mRNA stability by proteins that bind AU-rich elementsELAVL1;SET;ANP32A;ZFP36L1;TNPO1;SETB;KHSRP;ZFP36L1A;ZFP36L1B

KHSRP has several biochemical functions, for example, DNA binding, RNA binding, mRNA 3-UTR binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KHSRP itself. We selected most functions KHSRP had, and list some proteins which have the same functions with KHSRP. You can find most of the proteins on our site.

Function Related Protein
DNA bindingDDB2;PML;HMGA1;HMBOX1;KIF4;TCF25;SOX1;ZNF45;NR0B1
RNA bindingZNF74;HNRNPA1L2;SRSF1A;RAD51AP1;HNRNPH1;HNRPKL;FBL;RPL29;ENDOU
mRNA 3-UTR bindingIGF2BP2;RNPS1;CSDA;ANGEL2;RBM24A;PUM1;SECISBP2;SERBP1;PUM2
mRNA bindingSSB;SRRM4;C1QBP;SNRPC;IGF2BP1;FYTTD1;EIF4ENIF1;THOC2;PCBP1
nucleic acid bindingSCRT1A;ZNF865;ZFP39;PRDM8B;RECQL5;GTF3AB;NELFE;ZSCAN4C;ZFP12
poly(A) RNA bindingTBCA;CISD2;PFN1;HIST1H1C;IGF2BP2;ZFP346;DIMT1;MARK2;WDR43

KHSRP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KHSRP here. Most of them are supplied by our site. Hope this information will be useful for your research of KHSRP.

SF1; Invs

Kirsten, A; Beck, S; et al. New Autoantibodies in pediatric opsocionus-myoclonus syndrome. AUTOIMMUNITY, PT B: NOVEL APPLICATIONS OF BASIC RESEARCH 1110:256-260(2007).
  • Q&As
  • Reviews

Q&As (7)

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How is KHSRP involved in the regulation of miRNA biogenesis? 10/19/2021

It assists in processing primary miRNAs to precursor miRNAs, influencing miRNA maturation.

What role does KHSRP play in mRNA decay? 03/03/2021

KHSRP promotes rapid mRNA decay, affecting gene expression.

What is the significance of KHSRP in cellular proliferation and differentiation? 02/27/2021

KHSRP plays a role in cellular transitions, impacting proliferation and differentiation.

Are there potential therapeutic applications targeting KHSRP? 08/08/2020

Modulating KHSRP activity could offer therapeutic benefits, particularly in cancer.

How does KHSRP contribute to RNA metabolism? 06/20/2020

It binds to RNA, facilitating the degradation of certain mRNAs and processing of miRNAs.

What are the primary biological functions of KHSRP? 03/30/2020

KHSRP regulates RNA metabolism, including mRNA stability and miRNA processing.

How is KHSRP implicated in cancer development? 01/24/2019

Dysregulation of KHSRP is associated with various cancers, influencing tumor behavior.

Customer Reviews (3)

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Reviews
08/15/2020

    Easy to use, effective.

    07/14/2020

      Delivered promptly, good condition.

      10/18/2019

        Quality product, very happy.

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