KHSRP
-
Official Full Name
KH-type splicing regulatory protein
-
Overview
The KHSRP gene encodes a multifunctional RNA-binding protein implicated in a variety of cellular processes, including;transcription, alternative pre-mRNA splicing, and mRNA localization (Min et al., 1997 (PubMed 9136930); Gherzi et al.,;2004 (PubMed 15175153)). -
Synonyms
KHSRP; KH-type splicing regulatory protein; far upstream element-binding protein 2; FBP2; FUBP2; FUSE binding protein 2; KSRP; p75; FUSE-binding protein 2; KH type-splicing regulatory protein; MGC99676;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- Zebrafish
- E.coli
- HEK293
- HEK293T
- Mamanlian cells
- Mammalian Cell
- Wheat Germ
- Flag
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- MYC
- Myc|DDK
- Involved Pathway
- Protein Function
- Interacting Protein
- KHSRP Related Articles
KHSRP involved in several pathways and played different roles in them. We selected most pathways KHSRP participated on our site, such as Gene Expression, KSRP (KHSRP) binds and destabilizes mRNA, Regulation of mRNA stability by proteins that bind AU-rich elements, which may be useful for your reference. Also, other proteins which involved in the same pathway with KHSRP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Gene Expression | ZNF317;ZNF625;RBB4L;CCNC;TRMT1;MBD3B;ZNF500;ZNF566;ZNF70 |
KSRP (KHSRP) binds and destabilizes mRNA | EXOSC8;DCP2;KHSRP |
Regulation of mRNA stability by proteins that bind AU-rich elements | ELAVL1;SET;ANP32A;ZFP36L1;TNPO1;SETB;KHSRP;ZFP36L1A;ZFP36L1B |
KHSRP has several biochemical functions, for example, DNA binding, RNA binding, mRNA 3-UTR binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KHSRP itself. We selected most functions KHSRP had, and list some proteins which have the same functions with KHSRP. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
DNA binding | DDB2;PML;HMGA1;HMBOX1;KIF4;TCF25;SOX1;ZNF45;NR0B1 |
RNA binding | ZNF74;HNRNPA1L2;SRSF1A;RAD51AP1;HNRNPH1;HNRPKL;FBL;RPL29;ENDOU |
mRNA 3-UTR binding | IGF2BP2;RNPS1;CSDA;ANGEL2;RBM24A;PUM1;SECISBP2;SERBP1;PUM2 |
mRNA binding | SSB;SRRM4;C1QBP;SNRPC;IGF2BP1;FYTTD1;EIF4ENIF1;THOC2;PCBP1 |
nucleic acid binding | SCRT1A;ZNF865;ZFP39;PRDM8B;RECQL5;GTF3AB;NELFE;ZSCAN4C;ZFP12 |
poly(A) RNA binding | TBCA;CISD2;PFN1;HIST1H1C;IGF2BP2;ZFP346;DIMT1;MARK2;WDR43 |
KHSRP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KHSRP here. Most of them are supplied by our site. Hope this information will be useful for your research of KHSRP.
SF1; Invs
- Q&As
- Reviews
Q&As (7)
Ask a questionIt assists in processing primary miRNAs to precursor miRNAs, influencing miRNA maturation.
KHSRP promotes rapid mRNA decay, affecting gene expression.
KHSRP plays a role in cellular transitions, impacting proliferation and differentiation.
Modulating KHSRP activity could offer therapeutic benefits, particularly in cancer.
It binds to RNA, facilitating the degradation of certain mRNAs and processing of miRNAs.
KHSRP regulates RNA metabolism, including mRNA stability and miRNA processing.
Dysregulation of KHSRP is associated with various cancers, influencing tumor behavior.
Customer Reviews (3)
Write a reviewEasy to use, effective.
Delivered promptly, good condition.
Quality product, very happy.
Ask a Question for All KHSRP Products
Required fields are marked with *
My Review for All KHSRP Products
Required fields are marked with *