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LAMC1

  • Official Full Name

    Laminin Subunit Gamma-1

  • Overview

    Laminins are major proteins in the basal lamina (one of the layers of the basement membrane), a protein network foundation for most cells and organs. The laminins are an important and biologically active part of the basal lamina, influencing cell differen
  • Synonyms

    LAMA 1; LAMA; LAMA1; LAMB1; Lamc3; LAMC3_HUMAN; Laminin A chain; Laminin alpha 1; Laminin alpha 1 chain; Laminin B1 chain; Laminin subunit beta 1; Laminin subunit gamma-3; Laminin-12 subunit gamma; Laminin-14 subunit gamma; Laminin-15 subunit gamma; Laminin, gamma 1; laminin;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mamanlian cells
  • Mammalian Cell
  • Wheat Germ
  • C
  • His
  • Flag
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human LAMC1-12H Recombinant Human LAMC1 protein, MYC/DDK-tagged HEK293 Myc/DDK
Human LAMC1-27945TH Recombinant Human LAMC1 Wheat Germ N/A 39 amino acids
Human LAMC1-19H Recombinant Human LAMC1 protein, His-tagged E.coli His Ile521~Pro772
Human LAMC1-4827HCL Recombinant Human LAMC1 293 Cell Lysate HEK293 N/A
Human LAMC1-9215HFL Recombinant Full Length Human LAMC1 protein, Flag-tagged Mamanlian cells Flag
Human LAMC1-275HF Recombinant Full Length Human LAMC1 Protein In Vitro Cell Free System 39 amino acids
Human LAMC1-2632H Recombinant Human LAMC1 protein(1071-1400 aa), C-His-tagged E. coli C-His 1071-1400 aa
Human LAMC1-3869H Recombinant Human LAMC1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse Lamc1-232M Recombinant Mouse Lamc1 Protein, His-tagged E.coli His Glu1228~Arg1404
Mouse Lamc1-3748M Recombinant Mouse Lamc1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat Lamc1-233R Recombinant Rat Lamc1 Protein, His-tagged E.coli His Glu1283~Asp1551
Zebrafish LAMC1-9548Z Recombinant Zebrafish LAMC1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • LAMC1 Related Articles
  • LAMC1 Related Research Area

LAMC1 involved in several pathways and played different roles in them. We selected most pathways LAMC1 participated on our site, such as PIK-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with LAMC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
PIK-Akt signaling pathwayIFNA7;CCNE2;CREB5;IFNA17;FLT1;ITGA1;RELA;EIF4E2;YWHAB
Focal adhesionPIK3R3;PAK3;COL4A6;CCND2;COL27A1B;MYLPF;THBS4B;VWF;THBS3A
ECM-receptor interactionITGA4;ITGA1;COL5A2;VWF;FN1A;SV2A;ITGB8;COL2A1B;LAMB2
Prion diseasesLAMC1;FYN;PRNP;BAX;PRKACB;HSPA1A;C9;C1QC;C5
ToxoplasmosisIKBKB;HLA-DMB;TLR2;MAPK9;PIK3R1;Toxoplasma Gondii Dense Granule Protein 7;LDLR;TGFB3;CYCS
AmoebiasisSERPINB10;LAMC2;PLCB1;COL5A2;IFNG;TGFB2;ITGB2;SERPINB1;SERPINB9
Pathways in cancerFOXO1;CASP9;F2R;ARNT2;FLT3LG;LEF1;FGF5;AKT2;PDGFA
Small cell lung cancerITGA2B;PIK3CA;NFKBIA;XIAP;PTGS2;PIK3R3;BIRC3;TRAF6;LAMB4

LAMC1 has several biochemical functions, for example, extracellular matrix structural constituent, glycosphingolipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LAMC1 itself. We selected most functions LAMC1 had, and list some proteins which have the same functions with LAMC1. You can find most of the proteins on our site.

Function Related Protein
extracellular matrix structural constituentCOL4A4;EFEMP2;LAMC1;IMPG1;CD4;TINAGL1;COL1A1A;MEPE;FBN2B
glycosphingolipid bindingCel;LAMC1;LAMA1;LAMB1;LYN;SELP;SELL;Il2

LAMC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LAMC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of LAMC1.

SNAPIN; SNX2; PDIA3; SRPK1; LAMA5; ATF7IP; CENPU; TANK; CCDC53; cona_canen; PHKG2; PYHIN1

Paez, MC; Matsuura, E; et al. Laminin-1 (LM-111) in preeclampsia and systemic lupus erythematosus. AUTOIMMUNITY 46:14-20(2013).
Vafia, K; Groth, S; et al. Pathogenicity of Autoantibodies in Anti-p200 Pemphigoid. PLOS ONE 7:-(2012).
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