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LDB1

  • Official Full Name

    LIM domain binding 1

  • Overview

    LIM domain-binding protein 1 is a protein that in humans is encoded by the LDB1 gene.
  • Synonyms

    LDB1; LIM domain binding 1; LIM domain-binding protein 1; carboxy terminal LIM domain protein 2; CLIM2; NLI; Carboxyl Terminal LIM Domain Binding 2; CLIM 2; LIM domain binding factor CLIM2; Nuclear LIM Domain Interactor; xldb1; LDB-1; hLdb1; CLIM-2; OTTHUMP00000020360; nuclear LIM interactor; LIM domain-binding factor-1; LIM domain-binding factor CLIM2; carboxyl-terminal LIM domain-binding protein 2;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • E.coli
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • His|T7
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human LDB1-4792HCL Recombinant Human LDB1 293 Cell Lysate HEK293 N/A
Human LDB1-1680H Recombinant Human LDB1 protein, His & T7-tagged E.coli His/T7 Asp112~Gln411 (Accession # Q86U70)
Human LDB1-5262H Recombinant Human LDB1 Protein (Asp112-Gln411), N-His tagged E.coli N-His Asp112-Gln411
Mouse LDB1-9017M Recombinant Mouse LDB1 Protein Mammalian Cell His
Mouse LDB1-5018M Recombinant Mouse LDB1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse LDB1-5018M-B Recombinant Mouse LDB1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque LDB1-2484R Recombinant Rhesus monkey LDB1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque LDB1-2305R-B Recombinant Rhesus Macaque LDB1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque LDB1-2305R Recombinant Rhesus Macaque LDB1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Chicken LDB1-6627C Recombinant Chicken LDB1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • LDB1 Related Articles

LDB1 involved in several pathways and played different roles in them. We selected most pathways LDB1 participated on our site, such as Transcriptional misregulation in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with LDB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Transcriptional misregulation in cancerBCL6;HIST2H3A;BMP2K;ETV1;IL3;BCL2A1;TSPAN7;SSX2;HIST1H3C

LDB1 has several biochemical functions, for example, LIM domain binding, RNA polymerase II activating transcription factor binding, chromatin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LDB1 itself. We selected most functions LDB1 had, and list some proteins which have the same functions with LDB1. You can find most of the proteins on our site.

Function Related Protein
LIM domain bindingLDB2;CSRP2BP;LDB2A;ACTN2;RPH3AL;LDB1A;TLN1;RIPK2;LDB1
RNA polymerase II activating transcription factor bindingEP300;JUN;HIPK2;EOMES;POU1F1;SETD3;BEX1;HEY2;BHLHE40
chromatin bindingDNMT3B;CHD7;JARID2;MEN1;FOSL2;TWIST2;NIPBL;SP3;SREBF1
enhancer sequence-specific DNA bindingGATA1;KLF6A;SOX9;ATF2;KLF7B;TWIST1B;XBP1;SOX11;GATA3
enzyme bindingRCOR3;DAXX;FAM84B;NKX2-1;ATG3;ATF7;CBX1;HIST1H2AK;ZFP36
protein bindingNME7;HTR1B;DSCC1;THAP6;IL7R;MYD88;NHP2;SF3A3;FDX1L
protein homodimerization activityCUL3;IZUMO1;HMGCS1;KIF20B;DMRT1;BNIP3;FZD9;TCF4;TBX18
protein self-associationDVL2;ADAM8;AGTR1B;RSAD2;L1CAM;SYP;ACVR2A;AXIN1;MDH2
transcription corepressor activityTBL1XR1A;SNW1;E2F8;CTCF;MTA1;HDAC9;BCL11A;PPP1R13L;RYBP

LDB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LDB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of LDB1.

LMO2; LMO4; 4005; LMX1B; LMO1

Makarev, E; Gorivodsky, M; et al. Islet1 and Its Co-Factor Ldb1 Are Expressed in Quiescent Cells of Mouse Intestinal Epithelium. PLOS ONE 9:-(2014).
Tanaka, T; Sewell, H; et al. Single Domain Intracellular Antibodies from Diverse Libraries EMPHASIZING DUAL FUNCTIONS OF LMO2 PROTEIN INTERACTIONS USING A SINGLE VH DOMAIN. JOURNAL OF BIOLOGICAL CHEMISTRY 286:3707-3716(2011).
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