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LDL

  • Official Full Name

    Low Density Lipoprotein

  • Overview

    Low-density lipoprotein (LDL) is one of the five major groups of lipoproteins, which in order of size, largest to smallest, are chylomicrons, VLDL, IDL, LDL and HDL, that enable transport of lipids like cholesterol and triglycerides within the water-based bloodstream. Blood tests typically report LDL-C, the amount of cholesterol contained in LDL. In clinical context, mathematically calculated estimates of LDL-C are commonly used to estimate how much low density lipoproteins are driving progression of atherosclerosis. Direct LDL measurements are also available and better reveal individual issues but are less often promoted or done due to slightly higher costs and being available from only a couple of laboratories in the United States. In 28 March 2008, as part of a joint consensus statement by the ADA and ACC, direct LDL particle measurement by NMR was recognized as superior for assessing individual risk of cardiovascular events. Because previous studies showed that higher levels of LDL particles promote health problems and cardiovascular disease, they are often informally called the bad cholesterol particles, (as opposed to HDL particles, which are frequently referred to as good cholesterol or healthy cholesterol particles). A recent study has found that LDL is essential in building muscle during resistance training.
  • Synonyms

    CU2+-OX LDL; Cu2+ oxidised low density lipoprotein; Lipoprotein, Oxidized Low Density CU2+; LDL; Low-density lipoprotein;

  • Recombinant Proteins
  • Native Proteins
  • Assay Kits
  • Human
  • CHO
  • human plasma
  • Human plasma
  • Human Plasma
  • Plasma
  • His
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human LDL-1537H Human Low Density Lipoproteins Human plasma N/A
Human LDL-407H Native Human Low Density Lipoprotein, Acetylated, DiI labeled Human plasma N/A
Human LDL-246H Native Human Lipoproteins, Oxidized LDL (OX-LDL) Human Plasma N/A
Human LDL-242H Native Human Lipoproteins, High Density Human Plasma N/A
Human LDL-243H Native Human Lipoproteins, Intermediate Density Human Plasma N/A
Human LDL-394H Native Human Low Density Lipoprotein, Biotin labeled Human plasma N/A
Human LDL-247H Native Human Lipoproteins, Very Low Density Human Plasma N/A
Human LDL-245H Native Human Lipoproteins, Low Density Human Plasma N/A
Human LDL-393H Native Human Low Density Lipoprotein Human plasma N/A
Human LDL-396H Native Human Low Density Lipoprotein, DiI labeled Human plasma N/A
Human LDL-403H Native Human Low Density Lipoprotein, Oxidized, DiO labeled Human plasma N/A
Human LDL-405H Native Human Low Density Lipoprotein, Acetylated Human plasma N/A
Human LDL-406H Native Human Low Density Lipoprotein, Acetylated, Biotin labeled Human plasma N/A
Human LDL-400H Native Human Low Density Lipoprotein, High Oxidized Human plasma N/A
Human LDL-1538H Native Human Low-density lipoprotein human plasma N/A
Human LDL-401H Native Human Low Density Lipoprotein, Medium Oxidized, DiI labeled Human plasma N/A
Human LDL-402H Native Human Low Density Lipoprotein, High Oxidized, DiI labeled Human plasma N/A
Human LDL-185H Native Human Low Density Lipoprotein, acetylated, DiI Human plasma N/A
Human LDL-399H Native Human Low Density Lipoprotein, Oxidized Human plasma N/A
Human LDL-404H Native Human Low Density Lipoprotein, Oxidized, Biotin labeled Human plasma N/A
Human LDL-22H  Active Recombinant Human LDL Protein, His-tagged CHO His
Human LDL-333H Native Human LDL Protein Human Plasma N/A
Human LDL-12H Native Human LDL Protein Plasma Full Length
Kit-0512 LDL Uptake Cell-Based Assay Kit N/A
  • LDL Related Articles

LDL involved in several pathways and played different roles in them. We selected most pathways LDL participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with LDL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

LDL has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by LDL itself. We selected most functions LDL had, and list some proteins which have the same functions with LDL. You can find most of the proteins on our site.

Function Related Protein

LDL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LDL here. Most of them are supplied by our site. Hope this information will be useful for your research of LDL.

Tavori, H; Giunzioni, I; et al. PCSK9 inhibition to reduce cardiovascular disease risk: recent findings from the biology of PCSK9. CURRENT OPINION IN ENDOCRINOLOGY DIABETES AND OBESITY 22:126-132(2015).
Henne, KR; Ason, B; et al. Anti-PCSK9 Antibody Pharmacokinetics and Low-Density Lipoprotein-Cholesterol Pharmacodynamics in Nonhuman Primates Are Antigen Affinity-Dependent and Exhibit Limited Sensitivity to Neonatal Fc Receptor-Binding Enhancement. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 353:119-131(2015).
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