LDL
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Official Full Name
Low Density Lipoprotein
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Overview
Low-density lipoprotein (LDL) is one of the five major groups of lipoproteins, which in order of size, largest to smallest, are chylomicrons, VLDL, IDL, LDL and HDL, that enable transport of lipids like cholesterol and triglycerides within the water-based bloodstream. Blood tests typically report LDL-C, the amount of cholesterol contained in LDL. In clinical context, mathematically calculated estimates of LDL-C are commonly used to estimate how much low density lipoproteins are driving progression of atherosclerosis. Direct LDL measurements are also available and better reveal individual issues but are less often promoted or done due to slightly higher costs and being available from only a couple of laboratories in the United States. In 28 March 2008, as part of a joint consensus statement by the ADA and ACC, direct LDL particle measurement by NMR was recognized as superior for assessing individual risk of cardiovascular events. Because previous studies showed that higher levels of LDL particles promote health problems and cardiovascular disease, they are often informally called the bad cholesterol particles, (as opposed to HDL particles, which are frequently referred to as good cholesterol or healthy cholesterol particles). A recent study has found that LDL is essential in building muscle during resistance training. -
Synonyms
CU2+-OX LDL; Cu2+ oxidised low density lipoprotein; Lipoprotein, Oxidized Low Density CU2+; LDL; Low-density lipoprotein;
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- Native Proteins
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- CHO
- human plasma
- Human plasma
- Human Plasma
- Plasma
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- LDL Related Articles
LDL involved in several pathways and played different roles in them. We selected most pathways LDL participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with LDL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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LDL has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by LDL itself. We selected most functions LDL had, and list some proteins which have the same functions with LDL. You can find most of the proteins on our site.
Function | Related Protein |
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LDL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LDL here. Most of them are supplied by our site. Hope this information will be useful for your research of LDL.
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