LGALS8
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Official Full Name
lectin, galactoside-binding, soluble, 8
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Overview
This gene encodes a member of the galectin family. Galectins are beta-galactoside-binding animal lectins with conserved carbohydrate recognition domains. The galectins have been implicated in many essential functions including development, differentiation, cell-cell adhesion, cell-matrix interaction, growth regulation, apoptosis, and RNA splicing. This gene is widely expressed in tumoral tissues and seems to be involved in integrin-like cell interactions. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] -
Synonyms
LGALS8; lectin, galactoside-binding, soluble, 8; Gal-8; PCTA1; PCTA-1; Po66-CBP; galectin-8; galectin 8; galectin-8g; Po66 carbohydrate binding protein; po66 carbohydrate-binding protein; prostate carcinoma tumor antigen 1;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Cattle
- Chicken
- Human
- Mouse
- Rat
- Rhesus Macaque
- E. coli
- E.coli
- HEK293
- HEK293T
- Human
- Mammalian Cell
- Mammalian cells
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- N
- C
- Flag
- Involved Pathway
- Protein Function
- Interacting Protein
- LGALS8 Related Research Area
LGALS8 involved in several pathways and played different roles in them. We selected most pathways LGALS8 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with LGALS8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
LGALS8 has several biochemical functions, for example, carbohydrate binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LGALS8 itself. We selected most functions LGALS8 had, and list some proteins which have the same functions with LGALS8. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| carbohydrate binding | LAYN;FCN1;CNTN2;CANX;CLEC6A;CD72;Mgl2;NCAN;GALNTL1 |
| protein binding | BATF2;C9orf16;MAP3K9;SPATA7;PVR;LONRF3;KIAA1737;MGST1;TRIM32 |
LGALS8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LGALS8 here. Most of them are supplied by our site. Hope this information will be useful for your research of LGALS8.
CALCOCO2; TGIF1; APEH; TRIM23
- Q&As
- Reviews
Q&As (7)
Ask a questionLGALS8 is involved in immune system modulation, influencing immune cell activation and response.
LGALS8 interacts with a range of proteins, participating in diverse signaling pathways and cellular functions.
Genetic mutations in LGALS8 can lead to altered cell signaling, impacting various biological processes.
It plays a role in apoptosis regulation, affecting cell survival and death mechanisms.
Altered LGALS8 activity is associated with cancer development, influencing tumor cell survival and metastasis.
Targeting LGALS8 offers potential for treating diseases, including cancer, by modulating key cellular processes.
LGALS8, a galectin protein, is involved in modulating cell communication, particularly in cell-cell and cell-matrix interactions.
Customer Reviews (3)
Write a reviewExpertise shines, supports research progress.
Top-notch analysis, highly recommended for research projects.
Reliable data source, a research necessity.
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