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LHPP

  • Official Full Name

    phospholysine phosphohistidine inorganic pyrophosphate phosphatase

  • Overview

    LHPP is a member of the HAD-like hydrolase superfamily. It is a unique enzyme that hydrolyzes not only oxygen-phosphorus bonds in inorganic pyrophosphate but also nitrogen-phosphorus bonds in phospholysine, phosphohistidine and imidodiphosphate in vitro.
  • Synonyms

    LHPP; phospholysine phosphohistidine inorganic pyrophosphate phosphatase; HDHD2B; hLHPP; FLJ44846; FLJ46044; MGC117251; MGC142189; MGC142191;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • Mammalian Cell
  • Yeast
  • His
  • His (Fc)
  • Avi
  • SUMO
  • N/A
  • T7|His
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human LHPP-202H Recombinant Human MMRN2 protein, T7/His-tagged E.coli T7/His
Human LHPP-28094TH Recombinant Human LHPP, His-tagged E.coli His 270 amino acids
Human LHPP-1319H Recombinant Human Phospholysine PhosphoHistidine Inorganic Pyrophosphate Phosphatase, His-tagged E.coli His
Human LHPP-4753HCL Recombinant Human LHPP 293 Cell Lysate HEK293 N/A
Human LHPP-1745H Recombinant Human LHPP Protein (1-270 aa), His-tagged Yeast His 1-270 aa
Human LHPP-4820H Recombinant Human LHPP protein, His-SUMO-tagged E.coli His-SUMO 1-270aa
Mouse LHPP-9084M Recombinant Mouse LHPP Protein Mammalian Cell His
Mouse LHPP-5072M-B Recombinant Mouse LHPP Protein Pre-coupled Magnetic Beads HEK293
Mouse LHPP-5072M Recombinant Mouse LHPP Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat LHPP-3403R Recombinant Rat LHPP Protein Mammalian Cell His
Rat LHPP-3059R-B Recombinant Rat LHPP Protein Pre-coupled Magnetic Beads HEK293
Rat LHPP-3059R Recombinant Rat LHPP Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish LHPP-5731Z Recombinant Zebrafish LHPP Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • LHPP Related Articles

LHPP involved in several pathways and played different roles in them. We selected most pathways LHPP participated on our site, such as Oxidative phosphorylation, which may be useful for your reference. Also, other proteins which involved in the same pathway with LHPP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Oxidative phosphorylationNDUFS6;Atp5k;ATP4A;mt-Atp8;ATP6V0E;COX7A3;COX6A2;UQCRC1;ATP4B

LHPP has several biochemical functions, for example, inorganic diphosphatase activity, magnesium ion binding, phosphohistidine phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by LHPP itself. We selected most functions LHPP had, and list some proteins which have the same functions with LHPP. You can find most of the proteins on our site.

Function Related Protein
inorganic diphosphatase activityPPA1A;PRUNE;PPA1;PPA1B;LHPP;PPA2
magnesium ion bindingRPS6KA2;RPS6KA5;CIB4;NT5C3A;THTPA;MTPAP;THG1L;FEN1;PRTFDC1
phosphohistidine phosphatase activityMINPP1;SGPP2;CTDSPL2A;PHPT1;PTPRQ;SACM1L;CTDSPL2B;SACM1LA;PXYLP1
protein homodimerization activityABCB9;FAM109B;RAB11FIP4;USH1G;DSCAML1;RASGRP1;AMBP;HINT2;NACC2

LHPP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LHPP here. Most of them are supplied by our site. Hope this information will be useful for your research of LHPP.

TNFRSF14

Koike, E; Toda, S; et al. Expression of new human inorganic pyrophosphatase in thyroid diseases: Its intimate association with hyperthyroidism. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 341:691-696(2006).
  • Q&As
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