LIM2
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Official Full Name
lens intrinsic membrane protein 2, 19kDa
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Overview
This gene encodes an eye lens-specific protein found at the junctions of lens fiber cells, where it may contribute to cell junctional organization. It acts as a receptor for calmodulin, and may play an important role in both lens development and cataractogenesis. Mutations in this gene have been associated with cataract formation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. -
Synonyms
LIM2; lens intrinsic membrane protein 2, 19kDa; lens intrinsic membrane protein 2 (19kD); lens fiber membrane intrinsic protein; MP17; MP19; Lens intrinsic membrane protein 2 19kDa; Lens intrinsic membrane protein 2; LIM 2; LMIP_HUMAN; MP18; MP20; To3;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Bos taurus (Bovine)
- Homo sapiens (Human)
- Human
- Mouse
- Mus musculus (Mouse)
- Rat
- Rattus norvegicus (Rat)
- E.coli
- E.coli expression system
- HEK293
- Mammalian Cell
- His
- His (Fc)
- Avi
- His|GST
- His|T7
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- LIM2 Related Articles
LIM2 involved in several pathways and played different roles in them. We selected most pathways LIM2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with LIM2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
LIM2 has several biochemical functions, for example, structural constituent of eye lens. Some of the functions are cooperated with other proteins, some of the functions could acted by LIM2 itself. We selected most functions LIM2 had, and list some proteins which have the same functions with LIM2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| structural constituent of eye lens | LIM2;ATXN1;CRYGF;CRYGS;MIP;ASL2;CRYGN1;CRYAB;CRYBB2 |
LIM2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LIM2 here. Most of them are supplied by our site. Hope this information will be useful for your research of LIM2.
- Q&As
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