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LIPF

Official Full Name

lipase, gastric
Overview

This gene encodes gastric lipase, an enzyme involved in the digestion of dietary triglycerides in the gastrointestinal tract, and responsible for 30% of fat digestion processes occurring in human. It is secreted by gastric chief cells in the fundic mucosa of the stomach, and it hydrolyzes the ester bonds of triglycerides under acidic pH conditions. The gene is a member of a conserved gene family of lipases that play distinct roles in neutral lipid metabolism. Several transcript variants encoding different isoforms have been found for this gene.
Synonyms

LIPF; lipase, gastric; gastric triacylglycerol lipase; HGL; HLAL; gastric lipase; GL; OTTHUMP00000020038; OTTHUMP00000020039;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat
Zebrafish

Source

E.coli
HEK293
HEK293T
Human Cell
In Vitro Cell Free System
Insect Cell
Mammalian Cell
Mammalian cells
Wheat Germ

Tag

C
His
GST
His (Fc)
Avi
His|GST
Myc
DDK
N/A
N

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	LIPF-101H	Recombinant Human LIPF, His-tagged	Insect Cell	His		Inquiry
Human	LIPE-8393H	Recombinant Human LIPF Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Human	LIPF-128H	Recombinant Human LIPF, His-tagged	HEK293	His		Inquiry
Human	LIPF-7939H	Recombinant Human LIPF protein, His & GST-tagged	E.coli	His/GST	Leu20~Lys398 (Accession # P07098)	Inquiry
Human	LIPF-292H	Recombinant Human LIPF, His-tagged	Insect Cell	His	Met1-Lys398	Inquiry
Human	LIPF-001HCL	Recombinant Human LIPF cell lysate	Human Cell	N/A		Inquiry
Human	LIPF-05H	Recombinant Human LIPF Protein, GST-tagged	Wheat Germ	GST	299-398	Inquiry
Human	LIPF-5218H	Recombinant Human LIPF Protein (Leu20-Lys398), C-His tagged	Mammalian cells	C-His	Leu20-Lys398	Inquiry
Human	LIPF-06H	Recombinant Human LIPF Protein, GST-tagged	Wheat Germ	GST	1-398	Inquiry
Human	LIPF-6863HF	Recombinant Full Length Human LIPF Protein, GST-tagged	In Vitro Cell Free System	GST	398 amino acids	Inquiry
Human	LIPF-5220H	Recombinant Human LIPF Protein (Leu20-Lys398), N-GST tagged	E.coli	N-GST	Leu20-Lys398	Inquiry
Mouse	LIPF-9129M	Recombinant Mouse LIPF Protein	Mammalian Cell	His		Inquiry
Mouse	LIPF-5099M	Recombinant Mouse LIPF Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	LIPF-5099M-B	Recombinant Mouse LIPF Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	LIPF-3418R	Recombinant Rat LIPF Protein	Mammalian Cell	His		Inquiry
Rat	LIPF-3074R	Recombinant Rat LIPF Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	LIPF-3074R-B	Recombinant Rat LIPF Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	LIPF-12578Z	Recombinant Zebrafish LIPF	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
LIPF Related Articles

LIPF involved in several pathways and played different roles in them. We selected most pathways LIPF participated on our site, such as Glycerolipid metabolism, Metabolic pathways, Fat digestion and absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with LIPF were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Glycerolipid metabolism	AGPAT2;AGPAT3;LPIN3;PPAP2D;GK;ALDH3A2;MBOAT2;AGPAT1;GK2
Metabolic pathways	GNSB;GFPT1;PTGIS;CYP4A10;FAXDC2;POLR3A;NME1;NAGLU;GPIB
Fat digestion and absorption	DGAT1;Cel;PLA2G5;PPAP2B;LIPF;PLA2G12B;FABP1;DGAT2;PNLIPRP2

LIPF has several biochemical functions, for example, lipid binding, malate dehydrogenase activity, triglyceride lipase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by LIPF itself. We selected most functions LIPF had, and list some proteins which have the same functions with LIPF. You can find most of the proteins on our site.

Function	Related Protein
lipid binding	OSBPL9;FNBP1;BPIFB1;CYTH2;DOK7;S1PR3;APOL6;PITPNM3;LIPF
malate dehydrogenase activity	LIPF;MDH1B;MDH1AA
triglyceride lipase activity	LPL;PNLIPRP1;LIPF;CES3;CES5A;PNPLA2;Cel;AADAC;LIPCA

LIPF has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LIPF here. Most of them are supplied by our site. Hope this information will be useful for your research of LIPF.

PSEN2

Luo, C; Zhu, YJ; et al. Carbonized Polyacrylonitrile-Stabilized SeSx Cathodes for Long Cycle Life and High Power Density Lithium Ion Batteries. ADVANCED FUNCTIONAL MATERIALS 24:4082-4089(2014).

Voigt, N; Stein, J; et al. The role of lipolysis in human orosensory fat perception. JOURNAL OF LIPID RESEARCH 55:870-882(2014).