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LPAR3

  • Official Full Name

    lysophosphatidic acid receptor 3

  • Overview

    This gene encodes a member of the G protein-coupled receptor family, as well as the EDG family of proteins. This protein functions as a cellular receptor for lysophosphatidic acid and mediates lysophosphatidic acid-evoked calcium mobilization. This receptor couples predominantly to G(q/11) alpha proteins.
  • Synonyms

    LPAR3; lysophosphatidic acid receptor 3; EDG7, endothelial differentiation, lysophosphatidic acid G protein coupled receptor, 7; Edg 7; HOFNH30; LP A3; LPA3; RP4 678I3; LPA-3; LPA receptor 3; LPA receptor EDG7; lysophosphatidic acid receptor Edg-7; endot;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human LPAR3-4023H Recombinant Human LPAR3 Protein, GST-tagged Wheat Germ GST
Human LPAR3-618H Recombinant Human LPAR3, GST-tagged E.coli GST C-60aa
Human LPAR3-4673HCL Recombinant Human LPAR3 293 Cell Lysate HEK293 N/A
Human LPAR3-4725H Recombinant Human LPAR3 Protein Wheat Germ N/A
Human LPAR3-5970HF Recombinant Full Length Human LPAR3 Protein In Vitro Cell Free System 600 amino acids
Human LPAR3-4693HF Recombinant Full Length Human LPAR3 Protein, GST-tagged In Vitro Cell Free System GST 353 amino acids
Human LPAR3-1187H Recombinant Human LPAR3 protein, His&Myc-tagged E.coli His&Myc 298-353aa
Rat LPAR3-3435R Recombinant Rat LPAR3 Protein Mammalian Cell His
Rat LPAR3-3091R-B Recombinant Rat LPAR3 Protein Pre-coupled Magnetic Beads HEK293
Rat LPAR3-3091R Recombinant Rat LPAR3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish LPAR3-8383Z Recombinant Zebrafish LPAR3 Mammalian Cell His
Chicken LPAR3-3809C Recombinant Chicken LPAR3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • LPAR3 Related Articles

LPAR3 involved in several pathways and played different roles in them. We selected most pathways LPAR3 participated on our site, such as Rap signaling pathway, Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with LPAR3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Rap signaling pathwayPLCB3;CDH1;FGFR3;VASP;ITGB2;SKAP1;HGF;PDGFD;ANGPT4
Phospholipase D signaling pathwayFCER1A;AVPR2;IL-8;AGPAT3;PLCB4;PIK3CG;KIT;AGPAT4;RALGDS
Neuroactive ligand-receptor interactionTAAR14F;P2RX3B;NPY1R;PRL;P2RX8;NMUR2;CHRNA3;CHRNB2;PRP2
PIK-Akt signaling pathwayKIT;BCL2;IFNAR1;PPP2R5C;PPP2R1B;PRL;MAPK3;PRLR;CCNE1
Pathways in cancerRUNX1;NKX3;ERBB2;FH1;LAMB2;WNT8B;FIGF;TFG;GNB1

LPAR3 has several biochemical functions, for example, G-protein alpha-subunit binding, G-protein coupled receptor activity, lipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LPAR3 itself. We selected most functions LPAR3 had, and list some proteins which have the same functions with LPAR3. You can find most of the proteins on our site.

Function Related Protein
G-protein alpha-subunit bindingDRD1;OPRM1;RIC8;LPAR1;HTR2A;ADRB2;DRD1A;F2RL1;CRHR1
G-protein coupled receptor activityGPR3;S1PR3;O3far1;PRLHR2B;GPR152;FZD8A;GNRHR2;SMO;TAAR14D
lipid bindingPITPNM3;ACBD4;ATP5G3;APOA2;Alb;CRABP1B;S1PR2;SEC14L3;APOC2
lysophosphatidic acid receptor activityLPAR1;LPAR2B;LPAR3;LPAR6A;LPAR2;LPAR2A
phospholipid bindingCPS1;ARHGAP44;WDFY4;APOA5;APOEA;LC3;AMPH;PAFAH2;Defa4

LPAR3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LPAR3 here. Most of them are supplied by our site. Hope this information will be useful for your research of LPAR3.

Shen, JY; Zhou, CL; et al. Comparative Transcriptome Analysis Reveals Early Pregnancy-Specific Genes Expressed in Peripheral Blood of Pregnant Sows. PLOS ONE 9:-(2014).
Uchida, H; Nagai, J; et al. Lysophosphatidic acid and its receptors LPA(1) and LPA(3) mediate paclitaxel-induced neuropathic pain in mice. MOLECULAR PAIN 10:-(2014).
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