lpar3
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  • Official Full Name
  • lysophosphatidic acid receptor 3
  • Background
  • This gene encodes a member of the G protein-coupled receptor family, as well as the EDG family of proteins. This protein functions as a cellular receptor for lysophosphatidic acid and mediates lysophosphatidic acid-evoked calcium mobilization. This receptor couples predominantly to G(q/11) alpha proteins.
  • Synonyms
  • LPAR3; lysophosphatidic acid receptor 3; EDG7, endothelial differentiation, lysophosphatidic acid G protein coupled receptor, 7; Edg 7; HOFNH30; LP A3; LPA3; RP4 678I3; LPA-3; LPA receptor 3; LPA receptor EDG7; lysophosphatidic acid receptor Edg-7; endot
Cat.#:LPAR3-4023HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human LPAR3 Protein, GST-tagged
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Cat.#:LPAR3-4725HTag:
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human LPAR3 Protein
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Cat.#:LPAR3-618HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human LPAR3, GST-tagged
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Cat.#:LPAR3-3435RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat LPAR3 Protein
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Cat.#:LPAR3-3809CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken LPAR3
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Cat.#:LPAR3-8383ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish LPAR3
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Cat.#:LPAR3-4673HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human LPAR3 293 Cell Lysate
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Cat.#:CSC-RG0285Tag:
Source (Host):Species:Human
Product nameHuman LPAR3-FLAG Stable Cell Line-RH7777
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Cat.#:CSC-RG0683Tag:
Source (Host):Species:Human
Product nameHuman LPAR3/Galpha15 Stable Cell Line-Chem-1
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Involved Pathway

LPAR3 involved in several pathways and played different roles in them. We selected most pathways LPAR3 participated on our site, such as Rap signaling pathway, Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with LPAR3 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Rap signaling pathway
PRKCI; LPAR5; FGF18; PDGFC; ARAP3; LPAR4; PRKCA; VEGFB; RAPGEF6; FARP2
Phospholipase D signaling pathway
TSC2; MTOR; AVP; PLA2G4C; FYN; GRM4; RAF1; PLCG1; CYTH1; GNAS
Neuroactive ligand-receptor interaction
CHRNA1; GABRR1; KISS1R; OPRD1B; PARD3; C3AR1; PTGER1; TAAR13B; PRSS3; TSHR
PIK-Akt signaling pathway
GNG8; IFNA10; TNXB; AKT1; YWHAB; GNG2; G6PC3; TEK; FGF9; GNGT2
Pathways in cancer
MMP9; GNG4; F2R; FGF7; GNA12; GNA11; PIK3R3; WNT5A; CDC42; WNT8A

Protein Function

LPAR3 has several biochemical functions, for example, G-protein alpha-subunit binding, G-protein coupled receptor activity, lipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LPAR3 itself. We selected most functions LPAR3 had, and list some proteins which have the same functions with LPAR3. You can find most of the proteins on our site.
Function
Related Protein
Function G-protein alpha-subunit binding
Related Protein LPAR3; LPAR1; F2R; NUCB1; AGTR1A; RGS4; CRHR1; OPRM1; DRD1A; F2RL1
Function G-protein coupled receptor activity
Related Protein GPR37B; GPR171; OLFR8; RXFP2A; OLFR507; OR51B5; TAS2R138; TM2D1; GPR12; MTNR1C
Function lipid binding
Related Protein RASGRP1; BAX; ACOT11; ATP5G1; UNC119B; CADPS; DNM1L; APOA1B; CRABP2A; DLC1
Function lysophosphatidic acid receptor activity
Related Protein LPAR1; LPAR2; LPAR6A; LPAR2A; LPAR3; LPAR2B
Function phospholipid binding
Related Protein OTC; PAFAH2; NSMAF; APOA1; SNCA; Defa4; BIN2; APOEB; NR5A1; PACSIN1

LPAR3 Related Articles

Shen, JY; Zhou, CL; et al. Comparative Transcriptome Analysis Reveals Early Pregnancy-Specific Genes Expressed in Peripheral Blood of Pregnant Sows. PLOS ONE 9:-(2014).
Uchida, H; Nagai, J; et al. Lysophosphatidic acid and its receptors LPA(1) and LPA(3) mediate paclitaxel-induced neuropathic pain in mice. MOLECULAR PAIN 10:-(2014).