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LPAR4

  • Official Full Name

    lysophosphatidic acid receptor 4

  • Overview

    This gene encodes a member of the lysophosphatidic acid receptor family. It may also be related to the P2Y receptors, a family of receptors that bind purine and pyrimidine nucleotides and are coupled to G proteins. The encoded protein may play a role in monocytic differentiation.
  • Synonyms

    LPAR4; lysophosphatidic acid receptor 4; G protein coupled receptor 23 , GPR23; LPA4; P2RY9; P2Y5 LIKE; P2Y9; LPA-4; LPA receptor 4; P2Y purinoceptor 9; P2Y5-like receptor; purinergic receptor 9; G protein-coupled receptor 23; G-protein coupled receptor 2;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • E.coli expression system
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human LPAR4-5971HF Recombinant Full Length Human LPAR4 Protein In Vitro Cell Free System 424 amino acids
Human LPAR4-4724H Recombinant Human LPAR4 Protein Wheat Germ N/A
Mouse LPAR4-9192M Recombinant Mouse LPAR4 Protein Mammalian Cell His
Mouse LPAR4-5135M-B Recombinant Mouse LPAR4 Protein Pre-coupled Magnetic Beads HEK293
Mouse LPAR4-5135M Recombinant Mouse LPAR4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Homo sapiens (Human) RFL26756HF Recombinant Full Length Human Lysophosphatidic Acid Receptor 4(Lpar4) Protein, His-Tagged E.coli expression system His Full Length (1-370)
Mus musculus (Mouse) RFL17293MF Recombinant Full Length Mouse Lysophosphatidic Acid Receptor 4(Lpar4) Protein, His-Tagged E.coli expression system His Full Length (1-370)
Chicken LPAR4-5330C Recombinant Chicken LPAR4 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • LPAR4 Related Articles

LPAR4 involved in several pathways and played different roles in them. We selected most pathways LPAR4 participated on our site, such as Rap signaling pathway, Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with LPAR4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Rap signaling pathwayMAPK13;GNAO1;VAV2;VEGFC;Fgf15;CDH1;LPAR2;FGF4;PIK3CD
Phospholipase D signaling pathwayPLCB2;GNA12;FCER1A;MRAS;DNM3;GNAS;CYTH2;MAP2K2;PDGFRB
Neuroactive ligand-receptor interactionCHRNA2A;HTR1E;F2RL3;GABRG1;HTR2C;ADCYAP1R1A;S1PR2;TACR1A;PTH1RA
PIK-Akt signaling pathwayGNG2;ITGA2B;GH1;PIK3CG;FIGF;VTN;MTCP1;TNC;ITGA1
Pathways in cancerBRAF;FZD2;FGF16;FZD3;RASSF1;HSP90AB1;LAMC1;CBL;MMP2

LPAR4 has several biochemical functions, for example, G-protein coupled receptor activity, lipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LPAR4 itself. We selected most functions LPAR4 had, and list some proteins which have the same functions with LPAR4. You can find most of the proteins on our site.

Function Related Protein
G-protein coupled receptor activityADRA2DA;RGRB;VMN1R52;OLFR149;TAAR13B;OR51B5;NPY;OLFR688;OXGR1A.2
lipid bindingAPOEB;C3;AP2A2;BPIFB1;ACBD5A;BAD;APOE;ESYT3;GLTP

LPAR4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LPAR4 here. Most of them are supplied by our site. Hope this information will be useful for your research of LPAR4.

BCL6

Hu, JC; Oda, SK; et al. Lysophosphatidic Acid Receptor 5 Inhibits B Cell Antigen Receptor Signaling and Antibody Response. JOURNAL OF IMMUNOLOGY 193:85-95(2014).
Ni, Y; Sinnett-Smith, J; et al. PKD1 Mediates Negative Feedback of PI3K/Akt Activation in Response to G Protein-Coupled Receptors. PLOS ONE 8:-(2013).
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