LSM1
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Official Full Name
LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae)
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Overview
This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Increased expression of this gene may play a role in cellular transformation and the progression of several malignancies including lung cancer, mesothelioma and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9. -
Synonyms
LSM1; LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae); U6 snRNA-associated Sm-like protein LSm1; anti-LSM1; Cancer associated Sm like protein; Cancer associated Sm-like; Cancer-associated Sm-like; CASM; Lsm1 protein; LSM1_HUMAN; Small nuclear ribonuclear CaSm; U6 snRNA associated Sm-like protein LSm1; YJL124C; cancer-associated Sm-like protein;
- Recombinant Proteins
- Cell & Tissue Lysates
- Human
- Mouse
- Zebrafish
- E. coli
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- C
- His
- GST
- Myc
- DDK
- N/A
- N
- T7
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | LSM1-3006H | Recombinant Human LSM1 Homolog, U6 Small Nuclear RNA Associated (S. Cerevisiae), T7-tagged | E.coli | T7 | ||
Human | LSM1-2818H | Recombinant Human LSM1, His-tagged | E.coli | His | ||
Human | LSM1-331H | Recombinant Human LSM1 protein(Met1-Tyr133), His-tagged | E. coli | N-His | Met1-Tyr133 | |
Human | LSM1-4613HCL | Recombinant Human LSM1 293 Cell Lysate | HEK293 | N/A | ||
Human | LSM1-6121HF | Recombinant Full Length Human LSM1 Protein, GST-tagged | In Vitro Cell Free System | GST | 133 amino acids | |
Human | LSM1-4618H | Recombinant Human LSM1 Protein, GST-tagged | Wheat Germ | GST | ||
Human | LSM1-618H | Recombinant Human LSM1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Myc/DDK | ||
Human | LSM1-4202H | Recombinant Human LSM1 Protein (Met1-Tyr133), C-His tagged | E.coli | C-His | Met1-Tyr133 | |
Mouse | Lsm1-3852M | Recombinant Mouse Lsm1 Protein, Myc/DDK-tagged | HEK293T | Myc/DDK | ||
Zebrafish | LSM1-985Z | Recombinant Zebrafish LSM1 | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- LSM1 Related Articles
LSM1 involved in several pathways and played different roles in them. We selected most pathways LSM1 participated on our site, such as Arginine and proline metabolism, Creatine metabolism, Glycine, serine and threonine metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with LSM1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Arginine and proline metabolism | SRM;CNDP1;PRODH2;DAO.2;NOS3;DHDPSL;P4HA1;ABP1;P4HA1B |
Creatine metabolism | SLC6A12;CKMT2A;CKM;CKMT2;CKB;SLC6A7;CKBA;CKMT1B;CKMB |
Glycine, serine and threonine metabolism | MAOA;DAO1;AGXTB;GCSHA;SRR;GCAT;PIPOX;PGAM1B;PSAT1 |
Metabolic pathways | ST3GAL6;GCNT1;CEPT1B;OGDHA;ctaG;RDH10A;CERS5;B4GALT7;NDUFC2-KCTD14 |
Metabolism | NUDT3;CYGB1;DECR1;HELZ2;APOA5;PDP2;GLS2B;GPHN;MED20 |
Metabolism of amino acids and derivatives | AZIN1A;DBH;SLC6A7;PPM1K;CDO1;SAT1B;CKMT1B;BCKDK;ACMSD |
Metabolism of polyamines | SLC6A7;CKBA;SAT1B;PAOX;OAZ1;CKMT2;SLC6A8;LSM1;OAZ2 |
Urea cycle and metabolism of amino groups | LSM1;CKB;CKM |
LSM1 has several biochemical functions, for example, S-adenosylmethionine-dependent methyltransferase activity, guanidinoacetate N-methyltransferase activity, protein homodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by LSM1 itself. We selected most functions LSM1 had, and list some proteins which have the same functions with LSM1. You can find most of the proteins on our site.
Function | Related Protein |
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S-adenosylmethionine-dependent methyltransferase activity | TPMT.1;LSM1;COQ5;ASMT2;METTL7A;C6orf211;PRMT8B;SUV39H1;PRMT7 |
guanidinoacetate N-methyltransferase activity | LSM1;GAMT |
protein homodimerization activity | BST2;MCL1;SH3GLB1;PRDM6;HLCS;ACTN4;CHMP3;MFF;TOX3 |
LSM1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LSM1 here. Most of them are supplied by our site. Hope this information will be useful for your research of LSM1.
LSM3; LSM4; CLIC1; NARS; HSP90AA1; PSMB8; PSMB5; LSM6; RRP1B; TMEM214; q81ky6_bacan; q81wx2_bacan; EXOSC8; FAM136A
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