lsm6
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  • Official Full Name
  • LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
  • Background
  • Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.
  • Synonyms
  • LSM6; LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae); U6 snRNA-associated Sm-like protein LSm6; YDR378C; LSM 6; LSM6 homolog U6 small nuclear RNA associated; Sm protein F; U6 snRNA associated Sm like protein LSm6; OTTHUMP00000220223; OTTHUMP00000220224; OTTHUMP00000220225; OTTHUMP00000221100
Cat.#:LSM6-4605HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human LSM6 Protein, GST-tagged
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Cat.#:LSM6-9335MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse LSM6 Protein
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Cat.#:LSM6-2586RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey LSM6 Protein, His-tagged
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Cat.#:LSM6-5611CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken LSM6
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Cat.#:LSM6-5612CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken LSM6
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Cat.#:LSM6-5613CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken LSM6
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Cat.#:LSM6-309ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish LSM6
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Cat.#:LSM6-9171HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human LSM6 293 Cell Lysate
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Involved Pathway

LSM6 involved in several pathways and played different roles in them. We selected most pathways LSM6 participated on our site, such as Deadenylation-dependent mRNA decay, Gene Expression, RNA degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with LSM6 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Deadenylation-dependent mRNA decay
EIF4E; C2orf29; TNKS1BP1; DCP2; EIF4EB; NT5C3B; DCP1B; EIF4A2; LSM6; PAIP1
Gene Expression
TSN; ZNF565; ZNF750; HNRNPH1; ZNF596; ZNF689; ZNF597; EIF2S3; SNAPC2; ZNF785
RNA degradation
PFKM; EXOSC8; CNOT7; EXOSC6; PAN3; PARN; CNOT8; CNOT1; PATL1; EXOSC4
Spliceosome
SLU7; PPIE; MAGOH2; SRSF7B; DHX15; HNRNPA3; TCERG1; SRSF2; SNRPC; SNRPE
mRNA decay by 5 to 3 exoribonuclease
DCP1B; LSM6; DDX6

Protein Function

LSM6 has several biochemical functions, for example, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LSM6 itself. We selected most functions LSM6 had, and list some proteins which have the same functions with LSM6. You can find most of the proteins on our site.
Function
Related Protein
Function poly(A) RNA binding
Related Protein MYO5A; TXN; UTP15; NOSIP; ZFP768; BUD13; STAU2; EIF4E2; ZCCHC9; ZYX
Function protein binding
Related Protein LRRC7; CBLN3; DOT1L; URM1; PRDX3; RXFP4; PSMF1; ATG12; SMC4; SNCAIP

Interacting Protein

LSM6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LSM6 here. Most of them are supplied by our site. Hope this information will be useful for your research of LSM6.
LSM5; CLNS1A; LSM3; SDCBP

LSM6 Related Articles

Perea-Resa, C; Hernandez-Verdeja, T; et al. LSM Proteins Provide Accurate Splicing and Decay of Selected Transcripts to Ensure Normal Arabidopsis Development. PLANT CELL 24:4930-4947(2012).
Novotny, I; Podolska, K; et al. Nuclear LSm8 affects number of cytoplasmic processing bodies via controlling cellular distribution of Like-Sm proteins. MOLECULAR BIOLOGY OF THE CELL 23:3776-3785(2012).