Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953 Learn More

LCN12

Official Full Name

lipocalin 12
Overview

Members of the lipocalin family, such as LCN12, have a common structure consisting of an 8-stranded antiparallel;beta-barrel that forms a cup-shaped ligand-binding pocket or calyx. Lipocalins generally bind small hydrophobic;ligands and transport them to specific cells (Suzuki et al., 2004 (PubMed 15363845)).
Synonyms

LCN12; lipocalin 12; epididymal-specific lipocalin-12; MGC48935; Lipocalcin 12; MGC34753;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat
Rhesus Macaque

Source

E.coli
HEK293
Mammalian Cell

Tag

GST
His
His (Fc)
Avi
His|GST
N/A
N

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	LCN12-975HCL	Recombinant Human LCN12 cell lysate		N/A		Inquiry
Human	LCN12-301442H	Recombinant Human LCN12 protein, GST-tagged	E.coli	GST	Asn406-Ile532	Inquiry
Human	LCN12-500H	Recombinant Human LCN12 Protein, His/GST-tagged	E.coli	His/GST	Leu61~Gly184	$298 / 10ug
Human	LCN12-4212H	Recombinant Human LCN12 Protein (Leu61-Gly184), N-GST tagged	E.coli	N-GST	Leu61-Gly184	Inquiry
Mouse	Lcn12-501M	Recombinant Mouse Lcn12 Protein, His/GST-tagged	E.coli	His/GST	Gln30~Cys193	$298 / 10ug
Rat	Lcn12-502R	Recombinant Rat Lcn12 Protein, His/GST-tagged	E.coli	His/GST	Ser21~Arg109+Gly151~Asp182	$298 / 10ug
Rhesus Macaque	LCN12-2477R	Recombinant Rhesus monkey LCN12 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	LCN12-2298R	Recombinant Rhesus Macaque LCN12 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rhesus Macaque	LCN12-2298R-B	Recombinant Rhesus Macaque LCN12 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein
LCN12 Related Articles

LCN12 involved in several pathways and played different roles in them. We selected most pathways LCN12 participated on our site, such as SLC-mediated transmembrane transport, Transmembrane transport of small molecules, Transport of fatty acids, which may be useful for your reference. Also, other proteins which involved in the same pathway with LCN12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
SLC-mediated transmembrane transport	SLC6A7;SLC4A1A;SLC36A2;SLC39A10;SLC30A2;SLC26A6L;SLCO1B1;SLC7A10;SLC9A6A
Transmembrane transport of small molecules	ANO9;LCN2;TRPM1;ANO4;SLC6A1B;SLC35A2;TRPC4;SLC5A8;SLC39A3
Transport of fatty acids	SLC27A4;APOD;LCN15;LCN12;LCN9;LCN1
Transport of vitamins, nucleosides, and related molecules	LCN12;SLC35A3A;SLC28A1;SLC35A3;SLC29A3;SLC28A3;SLCO2B1;SLCO2A1;SLCO4A1

LCN12 has several biochemical functions, for example, retinoic acid binding, transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by LCN12 itself. We selected most functions LCN12 had, and list some proteins which have the same functions with LCN12. You can find most of the proteins on our site.

Function	Related Protein
retinoic acid binding	LRAT;CRABP2A;LCN12;RARA;NR2F2;CYP26B1;UGT1A3;CRABP1A;SERPINA5
transporter activity	SLC13A4;SYPL;RLBP1A;AQP3;CRABP1;SLC6A18;SCARB1;APODB;ATP5G3

LCN12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LCN12 here. Most of them are supplied by our site. Hope this information will be useful for your research of LCN12.

MYC

Cheng, L; Xing, H; et al. Lipocalin-2 Promotes M1 Macrophages Polarization in a Mouse Cardiac Ischaemia-Reperfusion Injury Model. SCANDINAVIAN JOURNAL OF IMMUNOLOGY 81:31-38(2015).

Ginde, AA; Blatchford, PJ; et al. AGE-RELATED DIFFERENCES IN BIOMARKERS OF ACUTE INFLAMMATION DURING HOSPITALIZATION FOR SEPSIS. SHOCK 42:99-107(2014).