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LHB

  • Official Full Name

    luteinizing hormone beta polypeptide

  • Overview

    Luteinizing Hormone is a member of the glycoprotein hormone beta chain family. Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. Luteinizing Hormone is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism.
  • Synonyms

    CGB4; hLHB; LSH-B; Luteinizing Hormone (hLH) Beta Core Fragment; luteinizing hormone beta polypeptide; LHB;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Transfected Stable Cell Lines
  • Antibody
  • Native Proteins
  • Protein Pre-coupled Magnetic Beads
  • Bovine
  • Cynomolgus Monkey
  • Dog
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • CHO
  • E.coli
  • HEK293
  • HEK293 cells
  • HEK293T
  • Mammalian Cell
  • Mouse
  • Pituitary Gland
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • MYC
  • Myc|DDK
  • N/A
  • N
  • GST
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human LHB-1511H Recombinant Human LHB Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human LHB-7909H Recombinant Human LHB protein, His & T7-tagged E.coli His/T7 Glu23~Leu141 (Accession # P01229)
Human LHB-2831H Recombinant Human LHB Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human LHB-1522HCL Recombinant Human LHB Overexpression Cell Lysate HEK293T Myc/DDK
Human LHB-1091H Recombinant Human LHB Protein, His-tagged CHO N-His Glu23-Leu141
Human LHB-61H Luteinizing Hormone beta subunit Reference standard N/A
Human LHB-0027H Recombinant Human LHB Protein HEK293 cells
Human CAB074 Mouse anti-Luteinizing Hormone Monoclonal Antibody Mouse N/A
Human LHB-8212H Native Luteinizing Beta Subunit Hormone Pituitary Gland N/A
Mouse Lhb-1737M Recombinant Mouse Lhb Protein, His&GST-tagged E.coli N-His&GST Ser19-Leu139
Mouse Lhb-1316M Recombinant Mouse Lhb Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rat Lhb-7910R Recombinant Rat Lhb protein, His-tagged E.coli His Ser21~Phe141 (Accession # P01230)
Dog LHB-3173D Recombinant Dog LHB protein, His-tagged E.coli His 18-138aa
Bovine LHB-622B Recombinant Bovine LHB Protein (21-141 aa), His-tagged E.coli His 21-141 aa
Cynomolgus Monkey LHB-652C Recombinant Cynomolgus LHB Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey LHB-398C-B Recombinant Cynomolgus Monkey LHB Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey LHB-398C Recombinant Cynomolgus Monkey LHB Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish LHB-11657Z Recombinant Zebrafish LHB Mammalian Cell His
Zebrafish lhb-2739Z Recombinant Zebrafish lhb Protein, His-tagged E.coli N-His Leu24-Tyr140
LHB-840 Native Luteinizing Hormone, beta Subunit Pituitary Gland N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • LHB Related Articles

LHB involved in several pathways and played different roles in them. We selected most pathways LHB participated on our site, such as Neuroactive ligand-receptor interaction, GnRH signaling pathway, Ovarian steroidogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with LHB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Neuroactive ligand-receptor interactionGABRG3;TAAR12B;TAAR14E;NPFFR2;TACR3L;ADRB3A;PTH1RB;TAAR12J;VIPR1B
GnRH signaling pathwayCALM;CALM2;ATF4B1;CDC42L;MAPK10;MMP2;GNA11B;CALM1;MAP2K7
Ovarian steroidogenesisCYP2J5;PRKACA;INS;BMP6;HSD17B7;FSHB;ALOX5;INS1;ACOT2
Prolactin signaling pathwaySRC;SIRPA;PPIB;SOCS5;NRAS;INS2;MAPK11;INS1;AKT1

LHB has several biochemical functions, for example, hormone activity, receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LHB itself. We selected most functions LHB had, and list some proteins which have the same functions with LHB. You can find most of the proteins on our site.

Function Related Protein
hormone activityIGF3;LEPA;THPO;IAPP;BNP;INS2;INSL6;SST1.1;LHB
receptor bindingPDGFRB;TMED1;TNFSF13B;JAK2;UFD1L;IL1RAPL1;TGFB2;CTNND1;HIST2H3C2

LHB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LHB here. Most of them are supplied by our site. Hope this information will be useful for your research of LHB.

Cui, W; Mizukami, HP; et al. Glial Dysfunction in the Mouse Habenula Causes Depressive-Like Behaviors and Sleep Disturbance. JOURNAL OF NEUROSCIENCE 34:16273-16285(2014).
Reddy, A; May, E; et al. Latent hepatitis B is a risk factor for hepatocellular carcinoma in patients with chronic hepatitis C. WORLD JOURNAL OF GASTROENTEROLOGY 19:9328-9333(2013).
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