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LPAR5

  • Official Full Name

    lysophosphatidic acid receptor 5

  • Overview

    This gene encodes a member of the rhodopsin class of G protein-coupled transmembrane receptors. This protein transmits extracellular signals from lysophosphatidic acid to cells through heterotrimeric G proteins and mediates numerous cellular processes. Many G protein receptors serve as targets for pharmaceutical drugs. Transcript variants of this gene have been described.
  • Synonyms

    LPAR5; lysophosphatidic acid receptor 5; G protein coupled receptor 92 , GPR92, GPR93; KPG_010; LPA5; LPA-5; LPA receptor 5; G protein-coupled receptor 92; G-protein coupled receptor 92; G-protein coupled receptor 93; GPR92; GPR93;

  • Recombinant Proteins
  • Bos taurus (Bovine)
  • Homo sapiens (Human)
  • Human
  • Mus musculus (Mouse)
  • E.coli
  • E.coli expression system
  • In Vitro Cell Free System
  • Wheat Germ
  • GST
  • His
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human LPAR5-4723H Recombinant Human LPAR5 Protein Wheat Germ N/A
Human LPAR5-5525HF Recombinant Full Length Human LPAR5 Protein, GST-tagged In Vitro Cell Free System GST 372 amino acids
Human LPAR5-5278H Recombinant Human LPAR5 Protein, GST-tagged Wheat Germ GST
Human LPAR5-2975H Recombinant Human LPAR5 protein, His-tagged E.coli His 298-372 aa
Human LPAR5-5972HF Recombinant Full Length Human LPAR5 Protein In Vitro Cell Free System 295 amino acids
Bos taurus (Bovine) RFL24120BF Recombinant Full Length Bovine Lysophosphatidic Acid Receptor 5(Lpar5) Protein, His-Tagged E.coli expression system His Full Length (1-367)
Homo sapiens (Human) RFL13063HF Recombinant Full Length Human Lysophosphatidic Acid Receptor 5(Lpar5) Protein, His-Tagged E.coli expression system His Full Length (1-372)
Mus musculus (Mouse) RFL19986MF Recombinant Full Length Mouse Lysophosphatidic Acid Receptor 5(Lpar5) Protein, His-Tagged E.coli expression system His Full Length (1-372)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • LPAR5 Related Articles

LPAR5 involved in several pathways and played different roles in them. We selected most pathways LPAR5 participated on our site, such as Rap signaling pathway, Phospholipase D signaling pathway, PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with LPAR5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Rap signaling pathwayRAP1B;VEGFB;CDH1;PIK3R1;NGFR;FGF19;MET;PIK3R5;FGFR4
Phospholipase D signaling pathwayPLD2;MAPK3;IL-8;PIK3CD;GNAS;DGKE;CXCR1;GRM3;PIP5K1C
PIK-Akt signaling pathwayFGF6;LPAR2;ATF4;CASP9;BCL2;MDM2;COL6A4;LAMA2;FLT4
Pathways in cancerCasp3;IL6;TRAF5;TGFA;WNT3A;PIK3R3;PIAS2;RAF1;PTK2

LPAR5 has several biochemical functions, for example, G-protein coupled receptor activity, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by LPAR5 itself. We selected most functions LPAR5 had, and list some proteins which have the same functions with LPAR5. You can find most of the proteins on our site.

Function Related Protein
G-protein coupled receptor activityOR51B5;MC5RA;VMN1R50;OR7C1;COR1;GPR12;GPRC5A;OR5V1;OLFR498
molecular_functiona1BG;ACSM3;CCDC160;TPRN;FAM169AA;PSMD11A;ARPP21;TNNI2A.4;DESI1A

LPAR5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LPAR5 here. Most of them are supplied by our site. Hope this information will be useful for your research of LPAR5.

Yap, LF; Velapasamy, S; et al. Down-regulation of LPA receptor 5 contributes to aberrant LPA signalling in EBV-associated nasopharyngeal carcinoma. JOURNAL OF PATHOLOGY 235:456-465(2015).
Dong, Y; Hirane, M; et al. Lysophosphatidic acid receptor-5 negatively regulates cell motile and invasive activities of human sarcoma cell lines. MOLECULAR AND CELLULAR BIOCHEMISTRY 393:17-22(2014).
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