MAF1
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Official Full Name
MAF1 homolog (S. cerevisiae)
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Overview
This gene encodes a protein that is similar to Maf1, a Saccharomyces cerevisiae protein highly conserved in eukaryotic cells. Yeast Maf1 is a negative effector of RNA polymerase III (Pol III). It responds to changes in the cellular environment and represses pol III transcription. Biochemical studies identified the initiation factor TFIIIB as a target for Maf1-dependent repression. -
Synonyms
MAF1; MAF1 homolog (S. cerevisiae); repressor of RNA polymerase III transcription MAF1 homolog; DKFZp586G1123; homolog of yeast MAF1; MGC20332; MGC31779; MGC39758;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- Human
- Mammalian Cell
- His
- His (Fc)
- Avi
- SUMO
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- MAF1 Related Signal Pathway
MAF1 involved in several pathways and played different roles in them. We selected most pathways MAF1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MAF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
MAF1 has several biochemical functions, for example, GABA receptor binding, RNA polymerase III core binding, RNA polymerase III type 1 promoter DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MAF1 itself. We selected most functions MAF1 had, and list some proteins which have the same functions with MAF1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GABA receptor binding | ARFGEF2;MAF1;GABARAPA;GABARAPL2;GABARAP;PLCL1;GABRB1;TRAK1;GABRA5 |
| RNA polymerase III core binding | |
| RNA polymerase III type 1 promoter DNA binding | RPTOR;MTOR;MAF1 |
| RNA polymerase III type 2 promoter DNA binding | MTOR;MAF1;RPTOR |
| RNA polymerase III type 3 promoter DNA binding | MTOR;MAF1;RPTOR |
MAF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAF1.
ARMCX3; LAMTOR5; NUDT3; CCND3; SUMO2
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