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MAFB

  • Official Full Name

    v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B

  • Overview

    The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that plays an important role in the regulation of lineage-specific hematopoiesis. The encoded nuclear protein represses ETS1-mediated transcription of erythroid-specific genes in myeloid cells. This gene contains no introns. [provided by RefSeq, Jul 2008]
  • Synonyms

    MAFB; v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B; KRML; MCTO; transcription factor MafB; Kreisler maf-related leucine zipper homolog; MAFB/Kreisler basic region/leucine zipper transcription factor;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • E. coli
  • E.coli
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • N/A
  • T7|His
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MAFB-218H Recombinant Human MAFB protein, T7/His-tagged E.coli T7/His
Human MAFB-4561HCL Recombinant Human MAFB 293 Cell Lysate HEK293 N/A
Human MAFB-01H Recombinant Human MAFB protein, His-tagged E. coli His
Mouse MAFB-9438M Recombinant Mouse MAFB Protein Mammalian Cell His
Mouse MAFB-5297M-B Recombinant Mouse MAFB Protein Pre-coupled Magnetic Beads HEK293
Mouse MAFB-5297M Recombinant Mouse MAFB Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat MAFB-3534R Recombinant Rat MAFB Protein Mammalian Cell His
Rat MAFB-3190R Recombinant Rat MAFB Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat MAFB-3190R-B Recombinant Rat MAFB Protein Pre-coupled Magnetic Beads HEK293
Chicken MAFB-2547C Recombinant Chicken MAFB Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • MAFB Related Articles
  • MAFB Related Research Area

MAFB involved in several pathways and played different roles in them. We selected most pathways MAFB participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MAFB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

MAFB has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding, protein binding, transcription factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MAFB itself. We selected most functions MAFB had, and list some proteins which have the same functions with MAFB. You can find most of the proteins on our site.

Function Related Protein
RNA polymerase II core promoter proximal region sequence-specific DNA bindingDDIT3;ELF1;NDN;ETS2;CEBPA;NR2C1;NFE2L3;GATA4;SREBF2
protein bindingPDZD3;NXF2;MFN2;SPATA7;OPA1;TNKS;SUPV3L1;SLIRP;UBR4
transcription factor bindingHTT;TCF7L2;CEBPB;IFI203;RELA;NFIA;PAX6;CAMTA2;CREBBP
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific bindingMEF2C;FOSL1;PLAG1;FOXI1;HOXA5;NDN;POU2F3;NEUROD6;MEOX2
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific bindingEP300;ONECUT3;GRHL3;BARHL1B;DLX2;CSRNP1;PLAGL1;HSF2;MAFG

MAFB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAFB here. Most of them are supplied by our site. Hope this information will be useful for your research of MAFB.

HBZ; IRF3; BACH1; MAF; FOS; FOSL2; ATF3; NFE2L1; IKBKE; IRF7; ZWINT; prdm1_human_gene

Aida, Y; Shibata, Y; et al. Inhibition of Elastase-Pulmonary Emphysema in Dominant-Negative MafB Transgenic Mice. INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES 10:882-894(2014).
Herath, NI; Rocques, N; et al. GSK3-mediated MAF phosphorylation in multiple myeloma as a potential therapeutic target. BLOOD CANCER JOURNAL 4:-(2014).
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