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MAGEA12

Official Full Name

melanoma antigen family A, 12
Overview

This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Synonyms

MAGEA12; melanoma antigen family A, 12; MAGE12; melanoma-associated antigen 12; cancer/testis antigen family 1; member 12; CT1.12; MAGE-12 antigen; MAGE12F antigen; cancer/testis antigen 1.12; cancer/testis antigen family 1, member 12;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	MAGEA12-28504TH	Recombinant Human MAGEA12	Wheat Germ	N/A	314 amino acids	Inquiry
Human	MAGEA12-4556HCL	Recombinant Human MAGEA12 293 Cell Lysate	HEK293	N/A		Inquiry
Human	MAGEA12-294HF	Recombinant Full Length Human MAGEA12 Protein	In Vitro Cell Free System		314 amino acids	Inquiry
Human	MAGEA12-2410H	Recombinant Human MAGEA12 Protein, His-tagged	E.coli	N-His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
MAGEA12 Related Articles

MAGEA12 involved in several pathways and played different roles in them. We selected most pathways MAGEA12 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MAGEA12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

MAGEA12 has several biochemical functions, for example, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by MAGEA12 itself. We selected most functions MAGEA12 had, and list some proteins which have the same functions with MAGEA12. You can find most of the proteins on our site.

Function	Related Protein
molecular_function	COL28A1;VMN1R139;KCNQ1DN;TMEM179;CCM2L;CSMD3;FAM185A;CCDC149A;NEMF

MAGEA12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAGEA12 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAGEA12.

NS; STAT5A

Nerreter, T; Kochel, C; et al. Dasatinib enhances migration of monocyte-derived dendritic cells by reducing phosphorylation of inhibitory immune receptors Siglec-9 and Siglec-3. EXPERIMENTAL HEMATOLOGY 42:773-782(2014).

Zhang, QM; He, SJ; et al. Overexpression of MAGE-D4 in colorectal cancer is a potentially prognostic biomarker and immunotherapy target. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY 7:3918-3927(2014).