Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953 Learn More

MAN1A2

Official Full Name

mannosidase, alpha, class 1A, member 2
Overview

Alpha-mannosidases function at different stages of N-glycan maturation in mammalian cells. See MAN2A1 (MIM 154582) for general information.
Synonyms

MAN1A2; mannosidase, alpha, class 1A, member 2; mannosyl-oligosaccharide 1,2-alpha-mannosidase IB; MAN1B; Alpha 1,2 mannosidase IB; Mannosidase alpha class 1A member 2; Mannosyl oligosaccharide 1,2 alpha mannosidase IB; Processing alpha 1,2 mannosidase IB; alpha1,2-mannosidase; alpha-1,2-mannosidase IB; processing alpha-1,2-mannosidase IB;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Homo sapiens (Human)
Human
Mus musculus (Mouse)
Rhesus Macaque

Source

E.coli
E.coli expression system
HEK293
Mammalian Cell

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	MAN1A2-720H	Recombinant Human MAN1A2, GST-tagged	E.coli	GST	292-641aa	$319 / 25ug
Human	MAN1A2-1050HCL	Recombinant Human MAN1A2 cell lysate		N/A		Inquiry
Human	MAN1A2-477H	Recombinant Human MAN1A2 Protein, His-tagged	HEK293	His	Pro58-Arg641	Inquiry
Homo sapiens (Human)	RFL26323HF	Recombinant Full Length Human Mannosyl-Oligosaccharide 1,2-Alpha-Mannosidase Ib(Man1A2) Protein, His-Tagged	E.coli expression system	His	Full Length (1-641)	Inquiry
Mus musculus (Mouse)	RFL258MF	Recombinant Full Length Mouse Mannosyl-Oligosaccharide 1,2-Alpha-Mannosidase Ib(Man1A2) Protein, His-Tagged	E.coli expression system	His	Full Length (1-641)	Inquiry
Rhesus Macaque	MAN1A2-2656R	Recombinant Rhesus monkey MAN1A2 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	MAN1A2-2476R	Recombinant Rhesus Macaque MAN1A2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rhesus Macaque	MAN1A2-2476R-B	Recombinant Rhesus Macaque MAN1A2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein

MAN1A2 involved in several pathways and played different roles in them. We selected most pathways MAN1A2 participated on our site, such as Asparagine N-linked glycosylation, Metabolic pathways, Metabolism of proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with MAN1A2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Asparagine N-linked glycosylation	TRAPPC10;ALG2;TRAPPC2L;NANP;SERPINA1L;MAN1A2;AREG;MAN1B1;TRAPPC9
Metabolic pathways	CELL;COX8A;NDUFB10;HSD17B8;PIPOX;AMY2A3;BCO1L;PTGS2A;TYRP1
Metabolism of proteins	KCNA3;DPH2;WDR85;NSFB;SEC22C;LMCD1;DNAJC24;TIMM17A;ADAMTS15
N-Glycan biosynthesis	B4GALT1;ST6GAL1;B4GALT2;ZNF408;MGAT4A;ALG10;ALG6;MAN2A1;ALG10B
N-glycan trimming and elongation in the cis-Golgi
Post-translational protein modification	ANKRD28;ADAMTSL5;OTOP2;ADAMTS3;EIF5A;TRAPPC2;ALG2;PREB;ADAMTS8
Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2
Protein processing in endoplasmic reticulum	VIMP;UBE2E1;EDEM2;XBP1;ATXN3L;HSPA2;SEC31A;MAP2K7;PKZ

MAN1A2 has several biochemical functions, for example, calcium ion binding, mannosyl-oligosaccharide 1,2-alpha-mannosidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MAN1A2 itself. We selected most functions MAN1A2 had, and list some proteins which have the same functions with MAN1A2. You can find most of the proteins on our site.

Function	Related Protein
calcium ion binding	CALML4A;NKD2A;CASQ1B;CDH9;LTBP2;LETM1;DSG2;CIB1;PCDHB1
mannosyl-oligosaccharide 1,2-alpha-mannosidase activity	MAN1A2;EDEM1;EDEM2;MAN1C1;MAN1A1;MAN1A;MAN1B1

MAN1A2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAN1A2 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAN1A2.

FOS; SP1; GTF2F2; SMAD9