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MAOA

  • Official Full Name

    monoamine oxidase A

  • Overview

    This gene encodes monoamine oxidase A, an enzyme that degrades amine neurotransmitters, such as dopamine, norepinephrine, and serotonin. The protein localizes to the mitochondrial outer membrane. The gene is adjacent to a related gene on the opposite strand of chromosome X. Mutation in this gene results in monoamine oxidase deficiency, or Brunner syndrome.
  • Synonyms

    MAOA; monoamine oxidase A; amine oxidase [flavin-containing] A; Amine oxidase [flavin containing] A; AOFA_HUMAN; EC 1.4.3.4; flavin containingA; HGNC:6833; MAO A; MAO-A; Monoamine oxidase type A; RP1 201D17_B.2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Bos taurus (Bovine)
  • Canis lupus familiaris (Dog) (Canis familiaris)
  • Chicken
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Rat
  • Rattus norvegicus (Rat)
  • Baculovirus-Insect
  • E. coli
  • E.coli
  • E.coli expression system
  • E.Coli or Yeast
  • HEK293
  • Insect cells
  • Mammalian Cell
  • GST
  • His
  • His|T7
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MAOA-108H Active Recombinant Human MAOA Protein Insect cells
Human MAOA-729H Recombinant Human MAOA, GST-tagged E.coli GST 242-527AA
Human MAOA-4517HCL Recombinant Human MAOA 293 Cell Lysate HEK293 N/A
Human MAOA-33H Recombinant Human MAOA Protein, His-tagged E. coli His 1-497 aa
Human MAOA-0378H Active Recombinant Human MAOA protein, His-tagged Baculovirus-Insect His Glu2-Ser527
Mouse Maoa-2011M Recombinant Mouse Maoa protein, His-tagged E.coli His Gln229~Gly428 (Accession # Q64133)
Mouse Maoa-2012M Recombinant Mouse Maoa protein, His-tagged E.coli His Val16~Trp196 (Accession # Q64133)
Mouse MAOA-0377M Recombinant Mouse MAOA protein, His-tagged Baculovirus-Insect His Thr2-Ser526
Rat Maoa-3419R Recombinant Rat Maoa, His-tagged E.Coli or Yeast His 526
Rat Maoa-2013R Recombinant Rat Maoa protein, His & T7-tagged E.coli His/T7 Leu1~Ser497 (Accession # P21396)
Bos taurus (Bovine) RFL30335BF Recombinant Full Length Bovine Amine Oxidase [Flavin-Containing] A(Maoa) Protein, His-Tagged E.coli expression system His Full Length (1-527)
Canis lupus familiaris (Dog) (Canis familiaris) RFL1775CF Recombinant Full Length Dog Amine Oxidase [Flavin-Containing] A(Maoa) Protein, His-Tagged E.coli expression system His Full Length (1-527)
Homo sapiens (Human) RFL26003HF Recombinant Full Length Human Amine Oxidase [Flavin-Containing] A(Maoa) Protein, His-Tagged E.coli expression system His Full Length (1-527)
Rattus norvegicus (Rat) RFL19625RF Recombinant Full Length Rat Amine Oxidase [Flavin-Containing] A(Maoa) Protein, His-Tagged E.coli expression system His Full Length (1-526)
Chicken MAOA-2497C Recombinant Chicken MAOA Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • MAOA Related Articles
  • MAOA Related Research Area

MAOA involved in several pathways and played different roles in them. We selected most pathways MAOA participated on our site, such as Glycine, serine and threonine metabolism, Arginine and proline metabolism, Histidine metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with MAOA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Glycine, serine and threonine metabolismGCSHA;AGXTB;GATM;BPGM;GLDC;ALAS1;AMT;THA1;SARDH
Arginine and proline metabolismODC1;ALDH9A1A.1;GOT2A;LSM1;CNDP1;CKBB;DAO1;PYCRL;DAO.2
Histidine metabolismFTCD;ALDH9A1A.1;ALDH3A1;CNDP1;ABP1;HNMT;ALDH2.2;UROC1;MAOB
Tyrosine metabolismADH2-2;TYRP1;AOX2P;AOX3;FAHD1;MAOA;TPO;GOT2A;ALDH3B2
Phenylalanine metabolismKEG1;ALDH1A3;HPDB;IL4I1;GOT1;GOT2;GOT2B;PAH;GOT2A
Tryptophan metabolismAOC1;IL4I1;AANAT2;ALDH2.1;GCDH;AOX4;CMTM2A;AOX2P;ALDH9A1A.1
Drug metabolism - cytochrome PMGST1.2;ADH1;UGT1AB;FMO5;MAOB;GSTM4;AOX3L1;GSTA2;ALDH1A3
Metabolic pathwaysANPEP;MIBP;NT5E;UQCR11;CHSY3;DLAT;ASAH2;PAPSS2A;COQ2
Serotonergic synapseGNB2;CYP2D9;ALOX15B;GNAI1;PRKACG;GNG8;CYP2C55;GNG3;ALOX15
Dopaminergic synapseGNG2;PLCB1;PPP2R5E;KCNJ9;CREB3;MAOB;PLCB2;DRD1A;PPP2R3C
Cocaine addictionCREB3L2;PDYN;GRIN3B;BDNF;FOSB;GNAI1;PRKACA;DRD2;DLG4
AlcoholismHDAC10;HIST1H4M;HIST1H3F;HIST1H2AL;HDAC8;GNB4;H2AFV;HDAC1;FOSB

MAOA has several biochemical functions, for example, flavin adenine dinucleotide binding, primary amine oxidase activity, serotonin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MAOA itself. We selected most functions MAOA had, and list some proteins which have the same functions with MAOA. You can find most of the proteins on our site.

Function Related Protein
flavin adenine dinucleotide bindingIVD;GCDHA;AOX3;GCDH;MAOA;ACAD11;GFER;NOS1;CYB5R3
primary amine oxidase activityVCAM1;AOC3;ABP1;MAOB;AOC1;MAOA;AOC2
serotonin bindingHTR2B;HTR2A;HTR1E;HTR3A;HTR1F;HTR2C;MAOA;HTR1B

MAOA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAOA here. Most of them are supplied by our site. Hope this information will be useful for your research of MAOA.

clorgyline; kynuramine; NDRG1; A2M

Blakeley, PM; Capron, LE; et al. Maternal prenatal symptoms of depression and down regulation of placental monoamine oxidase A expression. JOURNAL OF PSYCHOSOMATIC RESEARCH 75:341-345(2013).
Vitalis, T; Alvarez, C; et al. Developmental expression pattern of monoamine oxidases in sensory organs and neural crest derivatives. JOURNAL OF COMPARATIVE NEUROLOGY 464:392-403(2003).
Denney, RM; Koch, H; et al. Association between monoamine oxidase A activity in human male shin fibroblasts and genotype of the MAOA promoter-associated variable number tandem repeat. HUMAN GENETICS 105:542-551(1999).
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