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MCM6

  • Official Full Name

    minichromosome maintenance complex component 6

  • Overview

    The MCM6 protein (minichromosome maintenance protein 6) is a nuclear 115 kD DNA-dependent ATPase. The MCM6 protein is a component of the DNA pre-replication complex that acts to allow DNA to undergo single round of replication per cell cycle. MCM6 togethe
  • Synonyms

    MCM6; minichromosome maintenance complex component 6; MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) , minichromosome maintenance deficient (mis5, S. pombe) 6 , minichromosome maintenance deficient 6 homolog (S. cer;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MCM6-28042TH Recombinant Human MCM6 Wheat Germ N/A 821 amino acids
Human MCM6-4416HCL Recombinant Human MCM6 293 Cell Lysate HEK293 N/A
Human MCM6-4519H Recombinant Human MCM6 Protein, GST-tagged Wheat Germ GST
Human MCM6-2727H Recombinant Human MCM6 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human MCM6-299HF Recombinant Full Length Human MCM6 Protein In Vitro Cell Free System 821 amino acids
Human MCM6-3398H Recombinant Human MCM6 protein, His-tagged E.coli His 471-821 aa
Human MCM6-6071HF Recombinant Full Length Human MCM6 Protein, GST-tagged In Vitro Cell Free System GST 821 amino acids
Mouse MCM6-9639M Recombinant Mouse MCM6 Protein Mammalian Cell His
Mouse Mcm6-3997M Recombinant Mouse Mcm6 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse MCM6-5414M Recombinant Mouse MCM6 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse MCM6-5414M-B Recombinant Mouse MCM6 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque MCM6-2705R Recombinant Rhesus monkey MCM6 Protein, His-tagged Mammalian Cell His
Rhesus Macaque MCM6-2525R Recombinant Rhesus Macaque MCM6 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque MCM6-2525R-B Recombinant Rhesus Macaque MCM6 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish MCM6-5241Z Recombinant Zebrafish MCM6 Mammalian Cell His
Chicken MCM6-1665C Recombinant Chicken MCM6 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • MCM6 Related Articles

MCM6 involved in several pathways and played different roles in them. We selected most pathways MCM6 participated on our site, such as DNA replication, Cell cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with MCM6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
DNA replicationRFC5;GINS1;RPA1;FEN1;POLE3;GINS3;RFC4;LIG1;DBF4
Cell cycleHIST2H3C;KAT5;HJURP;SYCE1;MAD1L1;CDC25B;SGOL2;MCM9;YWHAZ

MCM6 has several biochemical functions, for example, ATP binding, contributes_to ATP-dependent DNA helicase activity, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MCM6 itself. We selected most functions MCM6 had, and list some proteins which have the same functions with MCM6. You can find most of the proteins on our site.

Function Related Protein
ATP bindingTTBK1;SKIV2L2;PYGL;NLRP2;MYO5B;RAF1B;ITPKA;TSSK3;MUSK
contributes_to ATP-dependent DNA helicase activityMRE11A;MCM7;NBN;MCM4;RAD50;MCM6
identical protein bindingMTPAP;HOOK1;SERPINB1A;SP100;APIP;SNCA;VPS4B;STAT2;VCP
protein bindingANG;AGTR1;SMARCE1;GPBP1;ZFYVE20;PMS2;MEN1;WASF1;IL7
single-stranded DNA bindingMCM6;WBP11;HSPD1;RPA2;OBFC2B;NABP1;HNRNPDL;NABP1A;TREX1

MCM6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MCM6 here. Most of them are supplied by our site. Hope this information will be useful for your research of MCM6.

MCM2; MCMBP

Xu, YX; Fan, HY; et al. 17 beta-Estradiol enhances response of mice spleen B cells elicited by TLR9 agonist. CELLULAR IMMUNOLOGY 278:125-135(2012).
Calissano, C; Damle, RN; et al. Intraclonal Complexity in Chronic Lymphocytic Leukemia: Fractions Enriched in Recently Born/Divided and Older/Quiescent Cells. MOLECULAR MEDICINE 17:1374-1382(2011).
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