mcpt1
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  • Official Full Name
  • Mcpt1 mast cell protease 1
  • Background
  • MCP-1 belongs to the family of chemotactic cytokines.MCP-1 is expressed by monocytes, vascular endothelial cells, smooth muscle cells, glomerular mesangial cell, osteoblastic cells. MCP-1 has been shown to exhibit biological activities other than Chemotaxis. It can induce the proliferation and activation of killer cells known as CHAK. Elevated levels of MCP-1 are observed in atherosclerotic plaques that are rich in macrophages. The factor activates the tumoricidal activity of monocytes and macrophages in vivo. It regulates the expression of cell surface antigens (CD11c, CD11b) and the expression of cytokines (IL1, IL6). MCP-1 is a potent activator of human basophils, inducing degranulation and the release of histamines. In basophils activated by IL3, IL5 or GM-CSF MCP-1 enhances the synthesis of leukotriene C4.
  • Synonyms
  • MCPT1; mast cell protease 1; MMCP-1; Mcp-1; AV080368
Cat.#:Mcpt1-306MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Mcpt1, His tagged
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Cat.#:MCPT1-2749MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse MCPT1 cell lysate
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Protein Function

Mcpt1 has several biochemical functions, for example, hydrolase activity, peptidase activity, serine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Mcpt1 itself. We selected most functions Mcpt1 had, and list some proteins which have the same functions with Mcpt1. You can find most of the proteins on our site.
Function
Related Protein
Function hydrolase activity
Related Protein PPM1AB; CTSL.1; NUDT4B; ACY3.1; ABHD6B; CAPN2B; NPSN; MTMR1B; ENDOU2; PTPRDB
Function peptidase activity
Related Protein MMP30; MMP14A; CASPB; PRSS44; IHHA; CAPN2B; IWS1; HTRA1A; FURINA; CTSBB
Function serine-type endopeptidase activity
Related Protein PLG; RHBDD3; PROC; MMP8; PRSS54; LOC780933; HTRA1B; Acr; HGFA; PRSS2
Function serine-type peptidase activity
Related Protein HPN; TMPRSS7; KLK1B8; MCPT1; GZMF; KLK11; EGFBP2; TMPRSS11G; GZMK; TMPRSS11F