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MDFI

  • Official Full Name

    MyoD family inhibitor

  • Overview

    This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures.
  • Synonyms

    MDFI; MyoD family inhibitor; I mfa; inhibitor of MyoD family a; I MF; MDFI_HUMAN; Myogenic repressor I-mf; OTTHUMP00000016375; OTTHUMP00000016376; OTTHUMP00000196103; OTTHUMP00000196414; OTTHUMP00000196415; I-MF; I-mfa;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MDFI-6101HF Recombinant Full Length Human MDFI Protein, GST-tagged In Vitro Cell Free System GST 246 amino acids
Human MDFI-4504H Recombinant Human MDFI Protein, GST-tagged Wheat Germ GST
Mouse MDFI-9658M Recombinant Mouse MDFI Protein Mammalian Cell His
Mouse MDFI-5427M Recombinant Mouse MDFI Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse MDFI-5427M-B Recombinant Mouse MDFI Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque MDFI-2710R Recombinant Rhesus monkey MDFI Protein, His-tagged Mammalian Cell His
Rhesus Macaque MDFI-2530R Recombinant Rhesus Macaque MDFI Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque MDFI-2530R-B Recombinant Rhesus Macaque MDFI Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein

MDFI involved in several pathways and played different roles in them. We selected most pathways MDFI participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MDFI were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

MDFI has several biochemical functions, for example, protein binding, transcription factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MDFI itself. We selected most functions MDFI had, and list some proteins which have the same functions with MDFI. You can find most of the proteins on our site.

Function Related Protein
protein bindingPTPN23;NME5;AMHR2;RARS;OPRK1;ISOC2;MT1F;FBXW7;ACYP2
transcription factor bindingPURA;APBB3;RBL1;TRIB2;NFATC4;SUMO1;NLK;CEBPG;DOT1L

MDFI has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MDFI here. Most of them are supplied by our site. Hope this information will be useful for your research of MDFI.

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