mep1a
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  • Official Full Name
  • meprin A, alpha (PABA peptide hydrolase)
  • Background
  • Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes and in leukocytes and certain cancer cells. Mature meprins are oligomers of evolutionarily related, separately encoded alpha and/or beta subunits. Homooligomers of meprin-alpha are secreted; oligomers containing meprin-beta are associated with the plasma membrane. Substrates include bioactive peptides and extracellular matrix proteins.
  • Synonyms
  • MEP1A; meprin A, alpha (PABA peptide hydrolase); PPHA; meprin A subunit alpha; PPH alpha; endopeptidase-2; PABA peptide hydrolase; bA268F1.1 (meprin A alpha (PABA peptide hydrolase)); N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha;
Cat.#:MEP1A-12HTag:His
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human MEP1A protein, His-tagged
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Cat.#:MEP1A-148HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MEP1A Protein, His-tagged
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Cat.#:MEP1A-156HTag:His
Source (Host):NSO cellsSpecies:Human
Product nameRecombinant Human MEP1A, His-tagged
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Cat.#:MEP1A-3143HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human MEP1A, His tagged
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Cat.#:Mep1a-149MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Mep1a Protein, His-tagged
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Cat.#:Mep1a-2300MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Mep1a, His tagged
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Cat.#:Mep1a-609MTag:His
Source (Host):Baculovirus Sf21 Insect CellsSpecies:Mouse
Product nameRecombinant Mouse Mep1a Protein, His-tagged
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Cat.#:MEP1A-3648RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat MEP1A Protein
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Cat.#:MEP1A-5093CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken MEP1A
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Cat.#:MEP1A-2166HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human MEP1A cell lysate
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Cat.#:MEP1A-2510MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse MEP1A cell lysate
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Involved Pathway

MEP1A involved in several pathways and played different roles in them. We selected most pathways MEP1A participated on our site, such as Protein digestion and absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with MEP1A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Protein digestion and absorption
COL6A4; SLC1A1; ATP1A1; ATP1A4; CPA1; SLC38A2; SLC15A1; MEP1B; CTRL; SLC7A7

Protein Function

MEP1A has several biochemical functions, for example, metalloendopeptidase activity, protein binding, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MEP1A itself. We selected most functions MEP1A had, and list some proteins which have the same functions with MEP1A. You can find most of the proteins on our site.
Function
Related Protein
Function metalloendopeptidase activity
Related Protein YME1L1; BMP1A; THSD4; IDE; ADAM30; PITRM1; MEP1A.1; ADAMTS3; MMP13A; MME
Function protein binding
Related Protein GAB2; WDR24; SEMA3E; SCNN1B; RTKN; PNKP; SRMS; VPS26A; NFATC2; HSPA9
Function zinc ion binding
Related Protein KIAA0913; PHF23; FBLIM1; Adam6; MICAL2B; ZCCHC9; FHL3B; AKAP8; PDZRN3B; PEG10

Interacting Protein

MEP1A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MEP1A here. Most of them are supplied by our site. Hope this information will be useful for your research of MEP1A.
MMP9