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MFN1

  • Official Full Name

    mitofusin 1

  • Overview

    The protein encoded by this gene is a mediator of mitochondrial fusion. This protein and mitofusin 2 are homologs of the Drosophila protein fuzzy onion (Fzo). They are mitochondrial membrane proteins that interact with each other to facilitate mitochondrial targeting. [provided by RefSeq, Jul 2008]
  • Synonyms

    MFN1; mitofusin 1; hfzo1; hfzo2; mitofusin-1; fzo homolog; transmembrane GTPase MFN1; putative transmembrane GTPase; mitochondrial transmembrane GTPase FZO-2; mitochondrial transmembrane GTPase Fzo-1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • Rhesus Macaque
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mamanlian cells
  • Mammalian Cell
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MFN1-21H Recombinant Human MFN1 protein, MYC/DDK-tagged HEK293 Myc/DDK
Human MFN1-7949H Recombinant Human MFN1 protein, His & T7-tagged E.coli His/T7 Met1~Leu227 (Accession # Q8IWA4)
Human MFN1-4348HCL Recombinant Human MFN1 293 Cell Lysate HEK293 N/A
Human MFN1-4277H Recombinant Human MFN1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human MFN1-4382H Recombinant Human MFN1 Protein, GST-tagged Wheat Germ GST
Human MFN1-4279HFL Recombinant Full Length Human MFN1 protein, Flag-tagged Mamanlian cells Flag
Human MFN1-6197HF Recombinant Full Length Human MFN1 Protein, GST-tagged In Vitro Cell Free System GST 741 amino acids
Mouse MFN1-9784M Recombinant Mouse MFN1 Protein Mammalian Cell His
Mouse Mfn1-7950M Recombinant Mouse Mfn1 protein, His & T7-tagged E.coli His/T7 Met1~Ile234 (Accession # Q811U4)
Mouse Mfn1-4057M Recombinant Mouse Mfn1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse MFN1-5516M Recombinant Mouse MFN1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse MFN1-5516M-B Recombinant Mouse MFN1 Protein Pre-coupled Magnetic Beads HEK293
Rat MFN1-3666R Recombinant Rat MFN1 Protein Mammalian Cell His
Rat MFN1-3322R Recombinant Rat MFN1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat MFN1-3322R-B Recombinant Rat MFN1 Protein Pre-coupled Magnetic Beads HEK293
Homo sapiens (Human) RFL11889HF Recombinant Full Length Human Mitofusin-1(Mfn1) Protein, His-Tagged E.coli expression system His Full Length (1-741)
Mus musculus (Mouse) RFL9904MF Recombinant Full Length Mouse Mitofusin-1(Mfn1) Protein, His-Tagged E.coli expression system His Full Length (1-741)
Rattus norvegicus (Rat) RFL5313RF Recombinant Full Length Rat Mitofusin-1(Mfn1) Protein, His-Tagged E.coli expression system His Full Length (1-741)
Rhesus Macaque MFN1-2753R Recombinant Rhesus monkey MFN1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque MFN1-2574R-B Recombinant Rhesus Macaque MFN1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque MFN1-2574R Recombinant Rhesus Macaque MFN1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Chicken MFN1-2144C Recombinant Chicken MFN1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • MFN1 Related Research Area

MFN1 involved in several pathways and played different roles in them. We selected most pathways MFN1 participated on our site, such as Factors involved in megakaryocyte development and platelet production, Hemostasis, Mitophagy, which may be useful for your reference. Also, other proteins which involved in the same pathway with MFN1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Factors involved in megakaryocyte development and platelet productionIRF2;NFE2;KIF2B;PHF21A;GATA5;KIF5B;H3F3D;IRF2A;KIF22
HemostasisDOCK10;KIF22;ABHD12;STXBP3;HBBE3;CFHL2;IGF2B;AKAP1B;MFN2
MitophagyTOMM22;LC3;TOMM20;MAP1LC3B;TOMM7;MFN1;MFN2;TOMM70A;TOMM6
Pink/Parkin Mediated MitophagyMAP1LC3B;TOMM40;MTERFD1;MFN2;TOMM20;TOMM7;LC3;TOMM5;TOMM20B

MFN1 has several biochemical functions, for example, GTP binding, GTPase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MFN1 itself. We selected most functions MFN1 had, and list some proteins which have the same functions with MFN1. You can find most of the proteins on our site.

Function Related Protein
GTP bindingNOLC1;MFHAS1;RHOH;SAR1AB;TUBB2;ARL11;TRIM66;SRPR;RAP2B
GTPase activityTUBA4L;TUBB;GTPBP5;RHOT1A;RAB9B;RAB33B;RHOT1;ATL3;DNM1
protein bindingIFI30;PRCC;TRPC6;HSD3B7;CMKLR1;APC2;BID;MAPK10;EFHC1

MFN1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MFN1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MFN1.

Bak1; TSC22D1; MAVS; TMBIM4; glmU; BAK1; PLK2

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