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MGRN1

  • Official Full Name

    mahogunin, ring finger 1

  • Overview

    Mahogunin (MGRN1) is a C3HC4 RING-containing protein with E3 ubiquitin ligase activity in vitro.
  • Synonyms

    MGRN1; mahogunin, ring finger 1; E3 ubiquitin-protein ligase MGRN1; KIAA0544; RNF156; Mahogunin ring finger 1; Mahogunin RING finger protein 1; MGRN 1; MGRN1_HUMAN; Probable E3 ubiquitin protein ligase MGRN1; RING finger protein 156; RNF 156; probable E3 ubiquitin-protein ligase MGRN1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Sf9 Insect Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MGRN1-179H Recombinant Human MGRN1, GST-tagged Sf9 Insect Cell GST
Human MGRN1-4328HCL Recombinant Human MGRN1 293 Cell Lysate HEK293 N/A
Human MGRN1-1370H Recombinant Human MGRN1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human MGRN1-5307H Recombinant Human MGRN1 Protein, GST-tagged Wheat Germ GST
Human MGRN1-6520HF Recombinant Full Length Human MGRN1 Protein, GST-tagged In Vitro Cell Free System GST 576 amino acids
Mouse MGRN1-9819M Recombinant Mouse MGRN1 Protein Mammalian Cell His
Mouse Mgrn1-4063M Recombinant Mouse Mgrn1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse MGRN1-5543M Recombinant Mouse MGRN1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse MGRN1-5543M-B Recombinant Mouse MGRN1 Protein Pre-coupled Magnetic Beads HEK293
Rat MGRN1-3676R Recombinant Rat MGRN1 Protein Mammalian Cell His
Rat MGRN1-3332R Recombinant Rat MGRN1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat MGRN1-3332R-B Recombinant Rat MGRN1 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • MGRN1 Related Articles

MGRN1 involved in several pathways and played different roles in them. We selected most pathways MGRN1 participated on our site, such as Ubiquitin mediated proteolysis, which may be useful for your reference. Also, other proteins which involved in the same pathway with MGRN1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Ubiquitin mediated proteolysisUBE4A;ANAPC1;UBE2Q2;CDH1-A;CUL2;ANAPC5;TRIM37;FBXO2;SOCS1A

MGRN1 has several biochemical functions, for example, ligase activity, protein binding, ubiquitin protein ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MGRN1 itself. We selected most functions MGRN1 had, and list some proteins which have the same functions with MGRN1. You can find most of the proteins on our site.

Function Related Protein
ligase activityHECTD1;CCNB1IP1;SIAH2L;RNF115;HUWE1;SHPRH;CBLB;TRIM32;RTCB
protein bindingCAPN3;BET1;C12orf50;COL1A1;NPDC1;UBXN2B;ATF7;Abcb1b;VPS18
ubiquitin protein ligase activityCMTM2A;RNF7;FBXO30;MED21;RBX1;RNF144A;BTRC;RNF34;TRIM2
ubiquitin-protein transferase activityRNF11;FEM1A;PJA2;DTX3L;TRIM24;RNF43;LMO7;RNF213;FBXL5
zinc ion bindingZFYVE20;CPSF4;PARP1;BRF1;ZFP346;TRAF7;BIRC7;RXRGA;PIAS2

MGRN1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MGRN1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MGRN1.

TSG101; GDU1; UBE2D1; UBE2E1; UBE2G2; UBE2D3; UBE2D2; UBE2I; GDU7; GDU5; GDU6; TRIM74; GDU4

Chhangani, D; Nukina, N; et al. Mahogunin ring finger 1 suppresses misfolded polyglutamine aggregation and cytotoxicity. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1842:1472-1484(2014).
Srivastava, D; Chakrabarti, O; et al. Mahogunin-mediated alpha-tubulin ubiquitination via noncanonical K6 linkage regulates microtubule stability and mitotic spindle orientation. CELL DEATH & DISEASE 5:-(2014).
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