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MLLT10

Official Full Name

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
Overview

This gene encodes a transcription factor and has been identified as a partner gene involved in several chromosomal rearrangements resulting in various leukemias. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms

MLLT10; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10; myeloid/lymphoid or mixed lineage leukemia (trithorax (Drosophila) homolog); protein AF-10; AF10; type I AF10 protein; type IV AF;

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	MLLT10-4293HCL	Recombinant Human MLLT10 293 Cell Lysate	HEK293	N/A	Inquiry
Human	MLLT10-5391H	Recombinant Human MLLT10 Protein, GST-tagged	Wheat Germ	GST	Inquiry
Mouse	MLLT10-9885M	Recombinant Mouse MLLT10 Protein	Mammalian Cell	His	Inquiry
Mouse	MLLT10-5584M	Recombinant Mouse MLLT10 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Mouse	MLLT10-5584M-B	Recombinant Mouse MLLT10 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry

Involved Pathway
Protein Function
Interacting Protein
MLLT10 Related Articles

MLLT10 involved in several pathways and played different roles in them. We selected most pathways MLLT10 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MLLT10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

MLLT10 has several biochemical functions, for example, DNA binding, protein binding, transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MLLT10 itself. We selected most functions MLLT10 had, and list some proteins which have the same functions with MLLT10. You can find most of the proteins on our site.

Function	Related Protein
DNA binding	PAX6A;LIG4;ZNF471;ZNF764;GTF2F2A;POU3F3A;SIM1A;LIN28A;ASCL5
protein binding	ELAVL2;LMX1B;ZFPM2A;EBF1;EPHB4;LAMA1;RPS3;TCEA2;APOB
transcription factor activity, sequence-specific DNA binding	PHF5A;NFYC;ZFP322A;HOXD3A;ZSCAN4C;NR4A2B;ENO1;HOXD4;NKX2-5
zinc ion binding	TRIM3;KLF4;ADAMTSL1;ZDHHC1;DNPEP;TP53I3;TRIM74;BRF1B;TRIM43A

MLLT10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MLLT10 here. Most of them are supplied by our site. Hope this information will be useful for your research of MLLT10.

DOT1L; CTNNB1; NDEL1; TMPO; MLLT3; MLLT6; SKP1; Ube2i; MLLT1; Naa50; Scai; Mta1; ZNF526; Mllt1

Baird, JH; Minniti, CP; et al. Oscillatory haematopoiesis in adults with sickle cell disease treated with hydroxycarbamide. BRITISH JOURNAL OF HAEMATOLOGY 168:737-746(2015).

Lohsen, S; Majumder, P; et al. Common distal elements orchestrate CIITA isoform-specific expression in multiple cell types. GENES AND IMMUNITY 15:543-555(2014).