mllt3
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  • Official Full Name
  • myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)
  • Background
  • Note=A chromosomal aberration involving MLLT3 is associated with acute leukemias. Translocation t(9;11)(p22;q23) with MLL/HRX. The result is a rogue activator protein.
  • Synonyms
  • MLLT3; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3; AF9; YEATS3; protein AF-9; YEATS domain-containing protein 3; ALL1-fused gene from chromosome 9 protein; myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog); translocated to, 3;
Cat.#:MLLT3-5392HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human MLLT3 Protein, GST-tagged
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Cat.#:MLLT3-580HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human MLLT3 Protein, MYC/DDK-tagged
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Cat.#:MLLT3-264HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MLLT3 protein, GST-tagged
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Cat.#:MLLT3-265HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MLLT3 protein, GST-tagged
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Cat.#:MLLT3-266HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MLLT3 protein, GST-tagged
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Cat.#:MLLT3-908HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MLLT3, GST-tagged
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Cat.#:MLLT3-9887MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse MLLT3 Protein
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Cat.#:MLLT3-2550ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish MLLT3
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Cat.#:MLLT3-4292HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human MLLT3 293 Cell Lysate
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Involved Pathway

MLLT3 involved in several pathways and played different roles in them. We selected most pathways MLLT3 participated on our site, such as Transcriptional misregulation in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with MLLT3 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Transcriptional misregulation in cancer
SPINT1; MEIS1; Bcl2a1b; PBX1; PTCRA; NR4A3; HDAC1; RXRB; BIRC3; HIST1H3H

Protein Function

MLLT3 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MLLT3 itself. We selected most functions MLLT3 had, and list some proteins which have the same functions with MLLT3. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein PIK3CD; IFT20; KLKB1; GRB10; KHDRBS1; PDE1B; RECQL4; EXOSC10; AICDA; pab1

Interacting Protein

MLLT3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MLLT3 here. Most of them are supplied by our site. Hope this information will be useful for your research of MLLT3.
DOT1L; CDK9; AFF4; CCNT1; ELL2; MLLT1

MLLT3 Related Articles

Zhang, WZ; Yu, ZY; et al. An Af9 cis-element directly targets Dot1a to mediate transcriptional repression of the alpha ENaC gene. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY 304:F367-F375(2013).