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MLLT3

  • Official Full Name

    myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)

  • Overview

    Note=A chromosomal aberration involving MLLT3 is associated with acute leukemias. Translocation t(9;11)(p22;q23) with MLL/HRX. The result is a rogue activator protein.
  • Synonyms

    MLLT3; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3; AF9; YEATS3; protein AF-9; YEATS domain-containing protein 3; ALL1-fused gene from chromosome 9 protein; myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog); translocated to, 3;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • B2M
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MLLT3-264H Recombinant Human MLLT3 protein, GST-tagged E.coli GST
Human MLLT3-580H Recombinant Human MLLT3 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human MLLT3-265H Recombinant Human MLLT3 protein, GST-tagged E.coli GST
Human MLLT3-908H Recombinant Human MLLT3, GST-tagged E.coli GST N-term-348aa
Human MLLT3-266H Recombinant Human MLLT3 protein, GST-tagged E.coli GST
Human MLLT3-4292HCL Recombinant Human MLLT3 293 Cell Lysate HEK293 N/A
Human MLLT3-5392H Recombinant Human MLLT3 Protein, GST-tagged Wheat Germ GST
Human MLLT3-2384H Recombinant Human MLLT3 protein, His-B2M-tagged E.coli His-B2M 1-568aa
Human MLLT3-6365HF Recombinant Full Length Human MLLT3 Protein, GST-tagged In Vitro Cell Free System GST 568 amino acids
Human MLLT3-294H Recombinant Human MLLT3 protein, His-tagged E.coli His 574aa
Mouse MLLT3-9887M Recombinant Mouse MLLT3 Protein Mammalian Cell His
Mouse MLLT3-5586M Recombinant Mouse MLLT3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Mllt3-4092M Recombinant Mouse Mllt3 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse MLLT3-5586M-B Recombinant Mouse MLLT3 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish MLLT3-2550Z Recombinant Zebrafish MLLT3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • MLLT3 Related Articles

MLLT3 involved in several pathways and played different roles in them. We selected most pathways MLLT3 participated on our site, such as Transcriptional misregulation in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with MLLT3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Transcriptional misregulation in cancerSSX1;GOLPH3;BMP2K;MEF2C;MLLT3;LYL1;Aff1;BCL2L1;PML

MLLT3 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MLLT3 itself. We selected most functions MLLT3 had, and list some proteins which have the same functions with MLLT3. You can find most of the proteins on our site.

Function Related Protein
protein bindingSNX12;COL23A1;CCNB1IP1;ARID3B;KIAA1143;RAD51L3;F12;TFRC;PELI2

MLLT3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MLLT3 here. Most of them are supplied by our site. Hope this information will be useful for your research of MLLT3.

DOT1L; CDK9; AFF4; CCNT1; ELL2; MLLT1

Zhang, WZ; Yu, ZY; et al. An Af9 cis-element directly targets Dot1a to mediate transcriptional repression of the alpha ENaC gene. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY 304:F367-F375(2013).
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