MLLT3
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Official Full Name
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)
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Overview
Note=A chromosomal aberration involving MLLT3 is associated with acute leukemias. Translocation t(9;11)(p22;q23) with MLL/HRX. The result is a rogue activator protein. -
Synonyms
MLLT3; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3; AF9; YEATS3; protein AF-9; YEATS domain-containing protein 3; ALL1-fused gene from chromosome 9 protein; myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog); translocated to, 3;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Zebrafish
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- B2M
- Myc
- DDK
- Myc|DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- MLLT3 Related Articles
MLLT3 involved in several pathways and played different roles in them. We selected most pathways MLLT3 participated on our site, such as Transcriptional misregulation in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with MLLT3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Transcriptional misregulation in cancer | SSX1;GOLPH3;BMP2K;MEF2C;MLLT3;LYL1;Aff1;BCL2L1;PML |
MLLT3 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MLLT3 itself. We selected most functions MLLT3 had, and list some proteins which have the same functions with MLLT3. You can find most of the proteins on our site.
Function | Related Protein |
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protein binding | SNX12;COL23A1;CCNB1IP1;ARID3B;KIAA1143;RAD51L3;F12;TFRC;PELI2 |
MLLT3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MLLT3 here. Most of them are supplied by our site. Hope this information will be useful for your research of MLLT3.
DOT1L; CDK9; AFF4; CCNT1; ELL2; MLLT1
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