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MRPS24

Official Full Name

mitochondrial ribosomal protein S24
Overview

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. A pseudogene corresponding to this gene is found on chromosome 11. Read-through transcription exists between this gene and the upstream upregulator of cell proliferation (URGCP) gene.
Synonyms

MRPS24; mitochondrial ribosomal protein S24; 28S ribosomal protein S24, mitochondrial; HSPC335; MRP S24; mitochondrial 28S ribosomal protein S24; S24mt; bMRP47; MRP-S24; bMRP-47;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Zebrafish

Source

HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	MRPS24-4142HCL	Recombinant Human MRPS24 293 Cell Lysate	HEK293	N/A		Inquiry
Human	MRPS24-5613H	Recombinant Human MRPS24 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	MRPS24-6489HF	Recombinant Full Length Human MRPS24 Protein, GST-tagged	In Vitro Cell Free System	GST	167 amino acids	Inquiry
Mouse	MRPS24-10096M	Recombinant Mouse MRPS24 Protein	Mammalian Cell	His		Inquiry
Mouse	MRPS24-5720M	Recombinant Mouse MRPS24 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	MRPS24-5720M-B	Recombinant Mouse MRPS24 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	MRPS24-2846Z	Recombinant Zebrafish MRPS24	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
MRPS24 Related Articles

MRPS24 involved in several pathways and played different roles in them. We selected most pathways MRPS24 participated on our site, such as Mitochondrial translation, Mitochondrial translation elongation, Mitochondrial translation initiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRPS24 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Mitochondrial translation	MRPL50;MRPL53;MRPL49;MRPL37;MRPL44;MRPS27;MRPL54;MRPL47;CHCHD1
Mitochondrial translation elongation	MRPL38;GADD45GIP1;MRPS24;MRPL45;MRPS31;MRPS30;MRPL49;MRPL44;MRPS27
Mitochondrial translation initiation	MRPS30;MRPL54;MRPS36;MRPL46;MRPS25;MRPS28;MRPL51;MRPL39;MRPL41
Mitochondrial translation termination	MRPL48;PTCD3;MRPS22;MRPL37;MRPS28;MRPL42;MRPS23;MRPL38;MRPL52
Organelle biogenesis and maintenance	MRPS33;ICT1;CHCHD1;FBF1;TFB1M;TCTEX1D1;IFT20;IFT46;MRPL40

MRPS24 has several biochemical functions, for example, poly(A) RNA binding, structural constituent of ribosome. Some of the functions are cooperated with other proteins, some of the functions could acted by MRPS24 itself. We selected most functions MRPS24 had, and list some proteins which have the same functions with MRPS24. You can find most of the proteins on our site.

Function	Related Protein
poly(A) RNA binding	DUSP14;RPL15;SCG3;CPEB3;UTP18;SRSF12;NOL7;RBM4B;RPL7L1
structural constituent of ribosome	MRPL17;MRPL28;FAUA;MRPL36;MRP63;MRPL35;MRPS31;RPL7L1;MRPL2

MRPS24 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRPS24 here. Most of them are supplied by our site. Hope this information will be useful for your research of MRPS24.

DDX56; ICT1

Kocher, T; Schraml, P; et al. Identification of genes differentially expressed in melanoma sublines derived from a single surgical specimen characterised by different sensitivity to cytotoxic T-lymphocyte activity. SCHWEIZERISCHE MEDIZINISCHE WOCHENSCHRIFT 130:617-624(2000).

PURNELLE, B; COSTER, F; et al. THE SEQUENCE OF A 36 KB SEGMENT ON THE LEFT ARM OF YEAST CHROMOSOME-X IDENTIFIES 24 OPEN READING FRAMES INCLUDING - NUC1, PRP21 (SPP91), CDC6, CRY2, THE GENE FOR S24, A HOMOLOG TO THE ACONITASE GENE ACO1 AND 2 HOMOLOGS TO CHROMOSOME-III GENES. YEAST 10:1235-1249(1994).