MRPS33
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Official Full Name
mitochondrial ribosomal protein S33
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Overview
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the;mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They;have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed.;Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA.;Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in;biochemical properties, which prevents easy recognition by sequence homology. The 28S subunit of the mammalian;mitoribosome may play a crucial and characteristic role in translation initiation. This gene encodes a 28S subunit;protein that is one of the more highly conserved mitochondrial ribosomal proteins among mammals, Drosophila and C.;elegans. Splice variants that differ in the 5 UTR have been found for this gene; all variants encode the same;protein. Pseudogenes corresponding to this gene are found on chromosomes 1q, 4p, 4q, and 20q. -
Synonyms
MRPS33; mitochondrial ribosomal protein S33; 28S ribosomal protein S33, mitochondrial; CGI 139; S33mt; PTD003; CGI-139; MRP-S33; FLJ21123;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
MRPS33 involved in several pathways and played different roles in them. We selected most pathways MRPS33 participated on our site, such as Mitochondrial translation, Mitochondrial translation elongation, Mitochondrial translation initiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRPS33 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Mitochondrial translation | MTIF3;GFM2;MRPL38;MRPS36;MRPS23;MRPL37;MRPL52;MRPS22;MRPL49 |
| Mitochondrial translation elongation | MRPS25;MRPL51;TUFM;MRPL47;MRPS36;GADD45GIP1;MRPL54;MRPL41;MRPL48 |
| Mitochondrial translation initiation | MRPS23;MRPL39;MRPL51;MRPS36;MRPL54;MRPL50;MRPL44;CHCHD1;MRPS30 |
| Mitochondrial translation termination | MRRF;MRPS33;MRPL10;MRPS25;MRPL37;MRPS34;GADD45GIP1;MRPL41;MRPL51 |
| Organelle biogenesis and maintenance | TMEM67;BBS13;MKKS;CNGA2;MRPS34;MRPL51;TTC26;MRPL3;GFM1 |
MRPS33 has several biochemical functions, for example, structural constituent of ribosome. Some of the functions are cooperated with other proteins, some of the functions could acted by MRPS33 itself. We selected most functions MRPS33 had, and list some proteins which have the same functions with MRPS33. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| structural constituent of ribosome | MRPS18B;RPS3;RPS10;MRPL46;MRPL47;RPL35;MRPL1;RPL12;MRPL27 |
MRPS33 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRPS33 here. Most of them are supplied by our site. Hope this information will be useful for your research of MRPS33.
MDM2; SCHIP1; HNRNPU; CDKN2AIP
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