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MTMR1

Official Full Name

myotubularin related protein 1
Overview

This gene encodes a member of the myotubularin related family of proteins. Members of this family contain the consensus sequence for the active site of protein tyrosine phosphatases. Alternatively spliced variants have been described but their biological validity has not been determined.
Synonyms

MTMR1; myotubularin related protein 1; myotubularin-related protein 1; MTMR 1; Myotubularin related 1; OTTHUMP00000025855; OTTHUMP00000025856; OTTHUMP00000025864; OTTHUMP00000233786;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse

Source

HEK293
HEK293T
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
Myc
DDK
Myc|DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	MTMR1-1147HCL	Recombinant Human MTMR1 cell lysate		N/A		Inquiry
Human	MTMR1-5711H	Recombinant Human MTMR1 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	MTMR1-2192H	Recombinant Human MTMR1 Protein, MYC/DDK-tagged	HEK293	Myc/DDK		Inquiry
Human	MTMR1-6079H	Recombinant Human MTMR1 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Human	MTMR1-6533HF	Recombinant Full Length Human MTMR1 Protein, GST-tagged	In Vitro Cell Free System	GST	38 amino acids	Inquiry
Mouse	MTMR1-10201M	Recombinant Mouse MTMR1 Protein	Mammalian Cell	His		Inquiry
Mouse	MTMR1-5784M-B	Recombinant Mouse MTMR1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	Mtmr1-4214M	Recombinant Mouse Mtmr1 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Mouse	MTMR1-5784M	Recombinant Mouse MTMR1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry

Involved Pathway
Protein Function
Interacting Protein
MTMR1 Related Articles

MTMR1 involved in several pathways and played different roles in them. We selected most pathways MTMR1 participated on our site, such as Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system, which may be useful for your reference. Also, other proteins which involved in the same pathway with MTMR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Inositol phosphate metabolism	IPPK;OCRL;PLCD1;MTMR7B;TPI1B;MTMR7;NUDT11;PTENA;PLCB2
Metabolic pathways	CYP2P7;CYP3A5;RIMKLB;COX5AA;PLA2G2F;INPP5K;ST6GAL2A;GALNT4;GLUD2
Phosphatidylinositol signaling system	PI4KAA;CALM3B;TMEM55A;MTMR2;IP6K2;SYNJ2;PLCD1A;PIP5K1AB;PIK3C2A

MTMR1 has several biochemical functions, for example, phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity, phosphatidylinositol-3-phosphatase activity, protein tyrosine phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MTMR1 itself. We selected most functions MTMR1 had, and list some proteins which have the same functions with MTMR1. You can find most of the proteins on our site.

Function	Related Protein
phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	TENC1;CTDSPL2A;CTDSPL2B;SACM1LA;MTMR1B;SACM1LB;SACM1L;MTMR1;SGPP2
phosphatidylinositol-3-phosphatase activity	MTMR2;MTM1;FIG4;MTMR1B;MTMR3;MTMR1;MTMR1A;MTMR14;PTEN
protein tyrosine phosphatase activity	EVLA;CDC25D;DUSP13;PTP4A1;MTMR1A;CDC14A;EYA1;PTPN20;MTMR7A

MTMR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MTMR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MTMR1.

Lee, JU; Son, JY; et al. Crystallization and preliminary X-ray crystallographic analysis of the PH-GRAM domain of human MTMR4. ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS 70:1280-1283(2014).

Mohan, M; Chandra, LC; et al. miR-190b Is Markedly Upregulated in the Intestine in Response to Simian Immunodeficiency Virus Replication and Partly Regulates Myotubularin-Related Protein-6 Expression. JOURNAL OF IMMUNOLOGY 193:1301-1313(2014).