mtmr1
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  • Official Full Name
  • myotubularin related protein 1
  • Background
  • This gene encodes a member of the myotubularin related family of proteins. Members of this family contain the consensus sequence for the active site of protein tyrosine phosphatases. Alternatively spliced variants have been described but their biological validity has not been determined.
  • Synonyms
  • MTMR1; myotubularin related protein 1; myotubularin-related protein 1; MTMR 1; Myotubularin related 1; OTTHUMP00000025855; OTTHUMP00000025856; OTTHUMP00000025864; OTTHUMP00000233786
Cat.#:MTMR1-2192HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human MTMR1 Protein, MYC/DDK-tagged
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Cat.#:MTMR1-5711HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human MTMR1 Protein, GST-tagged
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Cat.#:MTMR1-10201MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse MTMR1 Protein
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Cat.#:MTMR1-1147HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human MTMR1 cell lysate
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Involved Pathway

MTMR1 involved in several pathways and played different roles in them. We selected most pathways MTMR1 participated on our site, such as Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system, which may be useful for your reference. Also, other proteins which involved in the same pathway with MTMR1 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Inositol phosphate metabolism
INPPL1; OCRL; IP6K3; PIK3C3; MTMR7A; PLCB4; PIP4K2A; PIP5KL1; NUDT4; MTMR6
Metabolic pathways
PIGYL; ATP6V1AA; HPGDS; IDS; PNPLA2; CD38; GALT; NAPRT1; PAFAH1B1B; APIP
Phosphatidylinositol signaling system
MTMR7B; INPP5A; PIK3R2; PIK3R3A; PIP5K1AB; CDS2; INPP5E; PIK3C3; DGKZ; MTMR2

Protein Function

MTMR1 has several biochemical functions, for example, phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity, phosphatidylinositol-3-phosphatase activity, protein tyrosine phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MTMR1 itself. We selected most functions MTMR1 had, and list some proteins which have the same functions with MTMR1. You can find most of the proteins on our site.
Function
Related Protein
Function phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
Related Protein SACM1LB; MTMR1A; MTMR1; SACM1LA; SACM1L; MTMR3; TENC1; PTPRQ; MTMR2; CTDSPL2B
Function phosphatidylinositol-3-phosphatase activity
Related Protein MTMR14; MTMR1; MTMR3; FIG4; MTMR2; PTEN; SACM1L; MTMR8; MTMR1B; MTM1
Function protein tyrosine phosphatase activity
Related Protein MTMR14; MTMR1; RNGTT; PTPN11A; CDC14B; DUSP14; PALD1A; MTMR6; DUSP7; LRP8

MTMR1 Related Articles

Lee, JU; Son, JY; et al. Crystallization and preliminary X-ray crystallographic analysis of the PH-GRAM domain of human MTMR4. ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS 70:1280-1283(2014).
Mohan, M; Chandra, LC; et al. miR-190b Is Markedly Upregulated in the Intestine in Response to Simian Immunodeficiency Virus Replication and Partly Regulates Myotubularin-Related Protein-6 Expression. JOURNAL OF IMMUNOLOGY 193:1301-1313(2014).