mtmr8
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  • Official Full Name
  • myotubularin related protein 8
  • Background
  • This gene encodes a member of the myotubularin-related family and is part of the MTMR6 subgroup. Family members are dual-specificity phosphatases and the encoded protein contains a phosphoinositide-binding domain (PID) and a SET-interacting domain (SID). Defects in other family members have been found in myotubular myopathic diseases.
  • Synonyms
  • MTMR8; myotubularin related protein 8; myotubularin-related protein 8; FLJ20126; FLJ60798
Cat.#:MTMR8-2182HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human MTMR8 Protein, MYC/DDK-tagged
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Cat.#:MTMR8-5723HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human MTMR8 Protein, GST-tagged
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Cat.#:MTMR8-1094HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MTMR8, GST-tagged
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Cat.#:MTMR8-1992CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken MTMR8
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Cat.#:MTMR8-10708ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish MTMR8
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Cat.#:MTMR8-1151HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human MTMR8 cell lysate
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Involved Pathway

MTMR8 involved in several pathways and played different roles in them. We selected most pathways MTMR8 participated on our site, such as Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system, which may be useful for your reference. Also, other proteins which involved in the same pathway with MTMR8 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Inositol phosphate metabolism
PLCH2; NUDT11; ISYNA1; ITPK1; PIP5KL1; MTMR2; INPPL1A; MTMR4; INPP5KA; NUDT3
Metabolic pathways
DSE; NOS2A; CYP2R1; DHRS9; PPAP2D; ADSSL; ACSM4; LCT; ATP6V1B1; CYP17A1
Phosphatidylinositol signaling system
PI4K2A; CALM2; CALM3B; MTMR7A; CALM1A; PPIP5K1; IMPA1; PIK3R3B; PIP4K2AA; PLCD1A

Protein Function

MTMR8 has several biochemical functions, for example, phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity, phosphatidylinositol-3-phosphatase activity, protein tyrosine phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MTMR8 itself. We selected most functions MTMR8 had, and list some proteins which have the same functions with MTMR8. You can find most of the proteins on our site.
Function
Related Protein
Function phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
Related Protein MTM1; MTMR1B; TENC1; MTMR2; MTMR1A; MTMR3; CTDSPL2B; NT5DC3; MTMR8; PXYLP1
Function phosphatidylinositol-3-phosphatase activity
Related Protein PTEN; MTMR8; MTMR1; MTMR1A; SACM1L; FIG4; MTMR1B; MTM1; MTMR3; MTMR14
Function protein tyrosine phosphatase activity
Related Protein EPM2A; PTPRDB; MTMR6; MTMR1B; CDC14C; DUSP10; DUSP14; PTP4A2B; EYA1; DUPD1

Interacting Protein

MTMR8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MTMR8 here. Most of them are supplied by our site. Hope this information will be useful for your research of MTMR8.
MTMR9

MTMR8 Related Articles

Sanchez-Juan, P; Bishop, MT; et al. Genome-wide study links MTMR7 gene to variant Creutzfeldt-Jakob risk. NEUROBIOLOGY OF AGING 33:-(2012).
Pridgeon, JW; Yeh, HY; et al. Global transcription analysis of vaccinated channel catfish following challenge with virulent Edwardsiella ictaluri. VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY 146:53-61(2012).