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MTMR8

Official Full Name

myotubularin related protein 8
Overview

This gene encodes a member of the myotubularin-related family and is part of the MTMR6 subgroup. Family members are dual-specificity phosphatases and the encoded protein contains a phosphoinositide-binding domain (PID) and a SET-interacting domain (SID). Defects in other family members have been found in myotubular myopathic diseases.
Synonyms

MTMR8; myotubularin related protein 8; myotubularin-related protein 8; FLJ20126; FLJ60798;

Type

Recombinant Proteins
Cell & Tissue Lysates

Species

Chicken
Human
Zebrafish

Source

E.coli
HEK293
HEK293T
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
Myc
DDK
Myc|DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	MTMR8-1094H	Recombinant Human MTMR8, GST-tagged	E.coli	GST	N-term-307aa	$319 / 25ug
Human	MTMR8-1151HCL	Recombinant Human MTMR8 cell lysate		N/A		Inquiry
Human	MTMR8-6546HF	Recombinant Full Length Human MTMR8 Protein, GST-tagged	In Vitro Cell Free System	GST	704 amino acids	Inquiry
Human	MTMR8-6481H	Recombinant Human MTMR8 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Human	MTMR8-5723H	Recombinant Human MTMR8 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	MTMR8-2182H	Recombinant Human MTMR8 Protein, MYC/DDK-tagged	HEK293	Myc/DDK		Inquiry
Zebrafish	MTMR8-10708Z	Recombinant Zebrafish MTMR8	Mammalian Cell	His		Inquiry
Chicken	MTMR8-1992C	Recombinant Chicken MTMR8	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
MTMR8 Related Articles

MTMR8 involved in several pathways and played different roles in them. We selected most pathways MTMR8 participated on our site, such as Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system, which may be useful for your reference. Also, other proteins which involved in the same pathway with MTMR8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Inositol phosphate metabolism	PLCB1;IMPA2;SYNJ2;NUDT11;MINPP1;PIP4K2AA;NUDT3B;ITPK1A;PIP5K1A
Metabolic pathways	AGPAT5;OGDHA;NDUFC1;PLA2G4F;POLR2C;DCXR;GFPT2;NME1;MMAB
Phosphatidylinositol signaling system	PLCD1;CALM2B;PIP5K1AA;PIP5K1C;PPIP5K1;MTMR4;PLCG1;PLCB1;PIP4K2C

MTMR8 has several biochemical functions, for example, phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity, phosphatidylinositol-3-phosphatase activity, protein tyrosine phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MTMR8 itself. We selected most functions MTMR8 had, and list some proteins which have the same functions with MTMR8. You can find most of the proteins on our site.

Function	Related Protein
phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	SACM1L;NT5DC3;PXYLP1;SACM1LA;PTPRQ;SGPP2;MTMR1B;MTMR2;MTMR8
phosphatidylinositol-3-phosphatase activity	MTMR2;SACM1L;FIG4;MTMR1A;MTMR1B;MTMR14;PTEN;MTMR8;MTMR3
protein tyrosine phosphatase activity	PTPREB;CDC14B;PTPRC;PTPRZ1;PTPN23A;PTP4A1;PTPRQ;PTPN2B;PTPMT1

MTMR8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MTMR8 here. Most of them are supplied by our site. Hope this information will be useful for your research of MTMR8.

MTMR9

Sanchez-Juan, P; Bishop, MT; et al. Genome-wide study links MTMR7 gene to variant Creutzfeldt-Jakob risk. NEUROBIOLOGY OF AGING 33:-(2012).

Pridgeon, JW; Yeh, HY; et al. Global transcription analysis of vaccinated channel catfish following challenge with virulent Edwardsiella ictaluri. VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY 146:53-61(2012).