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MTPAP

  • Official Full Name

    mitochondrial poly(A) polymerase

  • Overview

    The protein encoded by this gene is a member of the DNA polymerase type-B-like family. This enzyme synthesizes the 3 poly(A) tail of mitochondrial transcripts and plays a role in replication-dependent histone mRNA degradation.[provided by RefSeq, Jan 2011]
  • Synonyms

    MTPAP; mitochondrial poly(A) polymerase; PAPD1; SPAX4; poly(A) RNA polymerase, mitochondrial; TUTase 1; terminal uridylyltransferase 1; polynucleotide adenylyltransferase; PAP-associated domain-containing protein 1;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MTPAP-1280HCL Recombinant Human MTPAP cell lysate N/A
Mouse MTPAP-10216M Recombinant Mouse MTPAP Protein Mammalian Cell His
Mouse MTPAP-5793M-B Recombinant Mouse MTPAP Protein Pre-coupled Magnetic Beads HEK293
Mouse MTPAP-5793M Recombinant Mouse MTPAP Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • MTPAP Related Articles

MTPAP involved in several pathways and played different roles in them. We selected most pathways MTPAP participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MTPAP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

MTPAP has several biochemical functions, for example, ATP binding, UTP binding, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MTPAP itself. We selected most functions MTPAP had, and list some proteins which have the same functions with MTPAP. You can find most of the proteins on our site.

Function Related Protein
ATP bindingRIMKLA;ATP5A1;TOR2A;MYO7B;XRCC3;ATM;ABCG4B;GTF2F2;CAMK2B
UTP bindingMTPAP;HSP90AB1
identical protein bindingSTIM1;NOXO1;GRB7;LZTFL1;ABCD1;PTPRM;UBE2G2;CNTN2;CDC42BPA
magnesium ion bindingTDP2;CLYBL;BPNT1;ICK;NUAK2;PSPH;PGM1;MARK1;WEE2
manganese ion bindingMTPAP;B4GALT1;PPM1N;MPPE1;NUDT7;PPM1BB;GALNT1;PPM1B;GALNT3
poly(A) RNA bindingSRSF10;RPS19BP1;H1F0;WBSCR22;ZFP622;PTCD1;APOBEC3B;MFAP1B;NUDT16L1
polynucleotide adenylyltransferase activityMTPAP;PAPOLG;PAPOLA;TUT1;PAPOLB;PAPD7;PAPD4
protein bindingMOCS3;KPNA5;SLC1A5;BBS7;DSTN;RAB1A;RAD9B;IP6K2;EPS8
protein homodimerization activitySDS;CRYBA2;MSH2;TREX1;PSMD7;TCF12;G6PD;RQCD1;ATP2A1

MTPAP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MTPAP here. Most of them are supplied by our site. Hope this information will be useful for your research of MTPAP.

CALCOCO2; Azi2; TBK1; Dynll1; NPM1; RPL10; DYNLL1; ICT1

Roberge, S; Roussel, J; et al. TNF-alpha-mediated caspase-8 activation induces ROS production and TRPM2 activation in adult ventricular myocytes. CARDIOVASCULAR RESEARCH 103:90-99(2014).
Sirisha, VL; Sinha, M; et al. Menadione-induced caspase-dependent programmed cell death in the green chlorophyte Chlamydomonas reinhardtii. JOURNAL OF PHYCOLOGY 50:587-601(2014).
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