mtr
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  • Official Full Name
  • 5-methyltetrahydrofolate-homocysteine methyltransferase
  • Background
  • MTR encodes the enzyme 5-methyltetrahydrofolate-homocysteine methyltransferase. This enzyme, also known as cobalamin-dependent methionine synthase, catalyzes the final step in methionine biosynthesis. Mutations in MTR have been identified as the underlying cause of methylcobalamin deficiency complementation group G. [provided by RefSeq, Jul 2008]
  • Synonyms
  • MTR; 5-methyltetrahydrofolate-homocysteine methyltransferase; MS; HMAG; cblG; methionine synthase; cobalamin-dependent methionine synthase; vitamin-B12 dependent methionine synthase; 5-methyltetrahydrofolate-homocysteine methyltransferase 1;
Cat.#:MTR-1704HTag:His
Source (Host):YeastSpecies:Human
Product nameRecombinant Human MTR Protein (923-1265 aa), His-tagged
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Cat.#:MTR-2288MTag:His-SUMO-Myc
Source (Host):E. coliSpecies:Mycobacterium Tuberculosis
Product nameRecombinant Mycobacterium Tuberculosis MTR Protein (1-459 aa), His-SUMO-Myc-tagged
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Cat.#:MTR-487HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MTR Protein, His-tagged
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Cat.#:MTR-5731HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human MTR Protein, GST-tagged
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Cat.#:MTR-3817RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat MTR Protein
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Cat.#:MTR-2778CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken MTR
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Cat.#:MTR-9794ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish MTR
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Involved Pathway

MTR involved in several pathways and played different roles in them. We selected most pathways MTR participated on our site, such as Cysteine and methionine metabolism, Selenocompound metabolism, One carbon pool by folate, which may be useful for your reference. Also, other proteins which involved in the same pathway with MTR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cysteine and methionine metabolism
LDHA; CBSB; DNMT3; MDH1; BCAT1; GCLC; APIP; GOT2A; MTR; AGXT2
Selenocompound metabolism
PSTK; TRR1; SCLY; SEPHS1; MARS; SPS2; SEPSECS; PAPSS2B; MARS2; TXNRD2
One carbon pool by folate
MTHFD2; MTHFD1L; ST20-MTHFS; MTFMT; AMT; ALDH1L1; TYMS; MTHFD2L; SHMT1; SHMT2
Metabolic pathways
GCH1; HYKK; PFKP; UQCR11; ST6GAL2; ALDH2.1; HAAO; HAO2; AK4; CYP2P9
Biosynthesis of amino acids
TPI1A; PHGDH; MAT2B; ACO1; PCXB; PGAM1; GLULA; GOT2; PYCRL; PRPS1

MTR Related Articles

Colombo, GL; Castagna, A; et al. Cost analysis of initial highly active antiretroviral therapy regimens for managing human immunodeficiency virus-infected patients according to clinical practice in a hospital setting. THERAPEUTICS AND CLINICAL RISK MANAGEMENT 10:9-15(2014).
Gueant, JL; Caillerez-Fofou, M; et al. Molecular and cellular effects of vitamin B12 in brain, myocardium and liver through its role as co-factor of methionine synthase. BIOCHIMIE 95:1033-1040(2013).