muc16
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  • Official Full Name
  • mucin 16, cell surface associated
  • Background
  • CA-125 (cancer antigen 125 or carbohydrate antigen 125) also known as mucin 16 or MUC16 is a protein that in humans is encoded by the MUC16 gene. MUC16 is a member of the mucin family glycoproteins. CA-125 has found application as a tumor marker or biomarker that may be elevated in the blood of some patients with specific types of cancers, or other benign conditions. MUC16 (CA125) is a serum marker that is used routinely in gynecologic practice to monitor patients with ovarian cancer. It is a mullerian duct differentiation antigen that is overexpressed in epithelial ovarian cancer cells and secreted into the blood, although its expression is not entirely confined to ovarian cancer. Most biochemical studies have concluded that MUC16 is a high molecular mass glycoprotein, although estimates of its size range from 200?to 2000?kDa with smaller “subunits” being described by some investigators.
  • Synonyms
  • MUC16; mucin 16, cell surface associated; CA125; mucin-16; CA-125; MUC-16; CA125 ovarian cancer antigen; ovarian carcinoma antigen CA125; ovarian cancer-related tumor marker CA125; FLJ14303; Igovomab; Indimacis-125; 171656-50-1; Abagovomab; 792921-10-9
Cat.#:MUC16-43HTag:Fc-Avi
Source (Host):HEK293Species:Human
Product nameRecombinant Human MUC16 Protein, Fc-Avi-tagged, Biotinylated
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Cat.#:MUC16-42HTag:His
Source (Host):CHOSpecies:Human
Product nameRecombinant Human MUC16 Protein, His-tagged
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Cat.#:MUC16-5748HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human MUC16 Protein, GST-tagged
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Cat.#:MUC16-127HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MUC16 Protein, His-tagged
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Cat.#:MUC16-704HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MUC16 (Q72L) Protein, His-tagged
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Cat.#:MUC16-9382HTag:His
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human MUC16 protein, His-tagged
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Cat.#:Muc16-128MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Muc16 Protein, His-tagged
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Cat.#:CDA002Tag:
Source (Host):Human Ascites FluidSpecies:Human
Product nameNative Human MUC16 Protein
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Cat.#:MUC16-1852HTag:N/A
Source (Host):HumanSpecies:Human
Product nameNative Human Mucin 16, Cell Surface Associated
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Cat.#:MUC16-1HTag:
Source (Host):Human Ascites FluidSpecies:Human
Product nameNative Human MUC16 protein
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Cat.#:MUC16-5456HTag:N/A
Source (Host):HEK293Species:Human
Product nameNative Human Mucin 16, Cell Surface Associated
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MUC16 Related Articles

Sasaki, A; Akita, K; et al. Difference in mesothelin- binding ability of serum CA125 between patients with endometriosis and epithelial ovarian cancer. INTERNATIONAL JOURNAL OF CANCER 136:1985-1990(2015).
Ricardo, S; Marcos-Silva, L; et al. Detection of glyco-mucin profiles improves specificity of MUC16 and MUC1 biomarkers in ovarian serous tumours. MOLECULAR ONCOLOGY 9:503-512(2015).