MUTYH
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Official Full Name
mutY homolog
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Overview
Base excision repair (BER) proteins catalyze the removal of incorrect or damaged bases, including oxidized bases, from DNA. N-glycosylases specific to a given lesion remove the incorrect base as the first step in BER. MYH is the mammalian ortholog of E. c -
Synonyms
MUTYH; mutY homolog (E. coli); mutY (E. coli) homolog; A/G-specific adenine DNA glycosylase; MYH; CYP2C; MGC4416;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Rat
- E.coli
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | MUTYH-1116H | Recombinant Human MUTYH, His-tagged | E.coli | His | 187-535aa | |
| Human | MUTYH-106H | Recombinant Human MUTYH Protein, His-tagged | E.coli | His |
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| Human | MUTYH-4052HCL | Recombinant Human MUTYH 293 Cell Lysate | HEK293 | N/A |
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| Human | MUTYH-5765H | Recombinant Human MUTYH Protein, GST-tagged | Wheat Germ | GST |
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| Human | MUTYH-6582HF | Recombinant Full Length Human MUTYH Protein, GST-tagged | In Vitro Cell Free System | GST | 535 amino acids |
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| Rat | MUTYH-3826R | Recombinant Rat MUTYH Protein | Mammalian Cell | His |
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| Rat | MUTYH-3485R-B | Recombinant Rat MUTYH Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rat | MUTYH-3485R | Recombinant Rat MUTYH Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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- Involved Pathway
- Protein Function
- Interacting Protein
MUTYH involved in several pathways and played different roles in them. We selected most pathways MUTYH participated on our site, such as Base excision repair, which may be useful for your reference. Also, other proteins which involved in the same pathway with MUTYH were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Base excision repair | nth;PNKP;TDG;UNG;POLB;LIG3;PCNA;PARP1;PARP2 |
MUTYH has several biochemical functions, for example, 4 iron, 4 sulfur cluster binding, NOT MutLalpha complex binding, NOT MutLbeta complex binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MUTYH itself. We selected most functions MUTYH had, and list some proteins which have the same functions with MUTYH. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| 4 iron, 4 sulfur cluster binding | NUBP2;RTEL1;DPYD;POLE;DNA2;DEM1;ERCC2;NDUFS8B;MUTYH |
| NOT MutLalpha complex binding | |
| NOT MutLbeta complex binding | |
| MutSalpha complex binding | MUTYH;TREX1 |
| NOT MutSbeta complex binding | |
| hydrolase activity, acting on glycosyl bonds | SMPDL3B;HPSE2;LYZ1;SMPD1;Chil3;LCTLB;MAN1A;GALCA;HYAL6 |
| metal ion binding | GM5136;KLF16;CSNK2B;CSK;KSR2;ZBTB1;ARFGAP1;MSRB1A;ZFP330 |
| protein binding | C11orf67;PHF17;APPL1;KL;EIF5A2;PLD3;NMNAT1;PTPN11A;SUV39H2 |
MUTYH has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MUTYH here. Most of them are supplied by our site. Hope this information will be useful for your research of MUTYH.
HRAS; XPA; SEC61B; FANCC; BAAT; CYLC2; SMAD1; TSTD2; LRSAM1; TDRD7; MSANTD3
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