MYCN
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Official Full Name
v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
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Overview
This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. [provided by RefSeq, Jul 2008] -
Synonyms
MYCN; v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog; NMYC; ODED; MODED; N-myc; MYCNOT; bHLHe37; N-myc proto-oncogene protein; pp65/67; oncogene NMYC; neuroblastoma MYC oncogene; class E basic helix-loop-helix protein 37; neuroblastoma-derived v-myc avian myelocytomatosis viral related oncogene;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- Zebrafish
- E.coli
- HEK293
- In Vitro Cell Free System
- Insect Cell
- Mammalian Cell
- Sf9 insect cells
- Wheat Germ
- Yeast
- GST
- His
- His (Fc)
- Avi
- N/A
- N
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | MYCN-27993TH | Recombinant Human MYCN protein, GST-tagged | Wheat Germ | GST | ||
Human | MYCN-30409TH | Recombinant Human MYCN | Wheat Germ | N/A | 100 amino acids | |
Human | MYCN-4036HCL | Recombinant Human MYCN 293 Cell Lysate | HEK293 | N/A | ||
Human | MYCN-1468H | Recombinant Human MYCN Protein (1-464 aa), His-tagged | Yeast | His | 1-464 aa | |
Human | MYCN-3128H | Recombinant Human MYCN protein, His-tagged | E.coli | His | 289 - 464 aa | |
Human | MYCN-2244H | Recombinant Human MYCN protein, His-tagged | Insect Cell | His | 1-464aa | |
Human | MYCN-7006HF | Recombinant Full Length Human MYCN Protein, GST-tagged | In Vitro Cell Free System | GST | 464 amino acids | |
Human | MYCN-35H | Recombinant Human MYCN Protein (Full length), N-GST-tagged | Sf9 insect cells | N-GST | Full Length | |
Mouse | MYCN-10290M | Recombinant Mouse MYCN Protein | Mammalian Cell | His | ||
Mouse | MYCN-5832M-B | Recombinant Mouse MYCN Protein Pre-coupled Magnetic Beads | HEK293 | |||
Mouse | MYCN-5832M | Recombinant Mouse MYCN Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rat | MYCN-3841R | Recombinant Rat MYCN Protein | Mammalian Cell | His | ||
Rat | MYCN-3500R | Recombinant Rat MYCN Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rat | MYCN-3500R-B | Recombinant Rat MYCN Protein Pre-coupled Magnetic Beads | HEK293 | |||
Zebrafish | MYCN-11893Z | Recombinant Zebrafish MYCN | Mammalian Cell | His | ||
Chicken | MYCN-2766C | Recombinant Chicken MYCN | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- MYCN Related Articles
- MYCN Related Research Area
MYCN involved in several pathways and played different roles in them. We selected most pathways MYCN participated on our site, such as Transcriptional misregulation in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with MYCN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Transcriptional misregulation in cancer | GOLPH3;PLAU;ATM;RELA;TSPAN7;WHSC1;FEV;MYCN;NR4A3 |
MYCN has several biochemical functions, for example, DNA binding, protein binding, protein dimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MYCN itself. We selected most functions MYCN had, and list some proteins which have the same functions with MYCN. You can find most of the proteins on our site.
Function | Related Protein |
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DNA binding | ZFP523;RTEL1;MYO18A;RXRAA;ZNF483;ZFP39;SIX2B;TBX5;ZNF672 |
protein binding | TNNI1;CCDC60;FAM114A1;FAM167A;DRD2;GNAQ;VPS54;EFNB2;HIST2H3C |
protein dimerization activity | AHRR;POLR2J;GRIN2A;NPAS4;PPP3CB;DAO;ID2B;LMLN;STK3 |
transcription factor activity, sequence-specific DNA binding | SOX13;ZNF621;GTF2IRD1;SMAD5;HOXD10;NR1D2B;TA;GM239;NR6A1A |
MYCN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MYCN here. Most of them are supplied by our site. Hope this information will be useful for your research of MYCN.
AURKA; MAX; Aurka; CDKN2A; SIRT1
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