MR1
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Official Full Name
major histocompatibility complex, class I-related
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Overview
Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching. Release of soluble CD40L from platelets is partially regulated by GP IIb/IIIa, actin polymerization, and an matrix metalloproteinases (MMP) inhibitor-sensitive pathway. -
Synonyms
MR1; major histocompatibility complex, class I-related; HLALS, major histocompatibility complex, class I like sequence; major histocompatibility complex class I-related gene protein; Class I histocompatibility antigen like protein; HLALS; Major histocompatibility complex class I like sequence; Major histocompatibility complex class I related; Major histocompatibility complex class I related isoform CRA a; Major histocompatibility complex class I related isoform CRA c; Major histocompatibility complex class I related isoform CRA d; MHC class I like antigen MR 1; MHC class I like antigen MR1; MHC class I related protein 1 isoform B; MHC class I related protein 1 isoform C; MR 1; Mr1 protein; MR1B; MR1C; OTTHUMP00000033129; OTTHUMP00000033130; OTTHUMP00000033131; MHC class I-like antigen MR-1; MHC class I-related gene protein; MHC class-I related-gene protein; class I histocompatibility antigen-like;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- E.coli
- HEK293
- HEK293T
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- Flag
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- MYC
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- MR1 Related Articles
- MR1 Related Research Area
MR1 involved in several pathways and played different roles in them. We selected most pathways MR1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
MR1 has several biochemical functions, for example, MHC class I receptor activity, peptide antigen binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MR1 itself. We selected most functions MR1 had, and list some proteins which have the same functions with MR1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| MHC class I receptor activity | KLRF1;LILRB1;CD160;KIR3DS1;MR1 |
| peptide antigen binding | CD209;MHC1ZDA;MR1;HLA-DQA1;MHC1ZHA;HLA-F;BF2;MAML1;HLA-DRB4 |
| protein binding | RGS2;GALT;ESR2;NUPL1;PTGFRN;PRRG2;RINL;SMAGP;TMEM31 |
MR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MR1.
FATE1
- Q&As
- Reviews
Q&As (6)
Ask a questionChanges in MR1 levels may be useful for early diagnosis of the disease, monitoring of disease progression, and assessment of prognosis. By monitoring changes in MR1 levels, doctors can better understand the patient's disease status and develop a treatment plan accordingly.
There may not be a specific treatment that directly targets the regulation of MR1 levels. However, treatments for diseases or conditions associated with MR1 may indirectly affect MR1 levels. The specific treatment plan should be determined based on the patient's specific situation and the doctor's recommendation.
Abnormal levels of MR1 may be associated with increased risk, disease progression, or poor prognosis for a particular disease or condition. Specific disease associations need to be determined based on available clinical research and evidence.
Distinguishing between MR1 levels and disease requires in-depth research and analysis. Through clinical trials, epidemiological studies, and other relevant research methods, the strength of the association between changes in MR1 levels and the occurrence and progression of the disease can be determined.
Measuring MR1 levels usually requires the use of specific biotechnological methods such as blood tests, tissue sample analysis, or other body fluid testing methods. These methods allow for quantitative or qualitative analysis of MR1.
The level of MR1 may be affected by a variety of factors, including age, gender, genetic factors, environmental factors, lifestyle, etc. Understanding these influencing factors can help to interpret changes in MR1 levels more accurately.
Customer Reviews (3)
Write a reviewThe high purity of MR1 reduces impurity interference in the experiment.
The assay is very sensitive and allows for easy detection of trace amounts of protein.
The colleagues around me were full of praise, and the experimental effect was too good.
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