mras
Share
  • Official Full Name
  • muscle RAS oncogene homolog
  • Background
  • This gene encodes a member of the Ras family of small GTPases. These membrane-associated proteins function as signal transducers in multiple processes including cell growth and differentiation, and dysregulation of Ras signaling has been associated with many types of cancer. The encoded protein may play a role in the tumor necrosis factor-alpha and MAP kinase signaling pathways. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
  • Synonyms
  • MRAS; muscle RAS oncogene homolog; ras-related protein M-Ras; M RAs; R RAS3; RRAS3; FLJ42964; M-ras; Muscle and microspikes Ras; Muscle Ras oncogene homologue; R-ras3; Ras related protein MRas; Ras related protein RRas3; Ras-related protein R-Ras3; RASM_HUMAN; XRas
Cat.#:MRAS-5533HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human MRAS Protein, GST-tagged
+Inquiry
Cat.#:MRAS-1335HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Muscle RAS Oncogene Homolog, His-tagged
+Inquiry
Cat.#:MRAS-703HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MRAS (Q71L) Protein, His-tagged
+Inquiry
Cat.#:MRAS-885HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human MRAS
+Inquiry
Cat.#:MRAS-10011MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse MRAS Protein
+Inquiry
Cat.#:MRAS-2821RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey MRAS Protein, His-tagged
+Inquiry
Cat.#:MRAS-6059CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken MRAS
+Inquiry
Cat.#:MRAS-4213HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human MRAS 293 Cell Lysate
+Inquiry

Involved Pathway

MRAS involved in several pathways and played different roles in them. We selected most pathways MRAS participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRAS were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
MAPK signaling pathway
NTF4; RAC2; CD14; FGF18A; FGF8A; RPS6KA3; FGF6A; MAPK8; PPM1B; MAP2K2B
Ras signaling pathway
LOC608458; RASAL2; ANGPT4; GAB1; CDC42; RASSF1; MRAS; GNG5; BCL2L1; RRAS
Rap signaling pathway
ITGA2B; MAPK3; PRKCA; FGF18; ITGAM; CALM3; PRKCZ; CALML3; VAV2; FGF5
Phospholipase D signaling pathway
RHEB; KIT; PDGFRA; AGTR1B; PLA2G4A; AGTR1A; INS2; ARF6; RAF1; PPAP2A
Tight junction
MYHZ1.1; CASKA; PTENB; CLDNC; MYH6; CTNNA3; CASK; CLDN5A; MYL10; CLDNA
Regulation of actin cytoskeleton
FGF5; PIP5K1AA; CFL2; Itgam&Itgb2; PTK2AA; ITGA5; FGF10A; PIK3R5; MYL10; ACTN2B
HTLV-I infection
FZD2; HLA-E; APC; CCND2; WNT7A; H2-Q10; TERT; ATM; BUB1B; NFKB2
Proteoglycans in cancer
PDCD4; WNT9A; NRAS; SRC; IGF2; FGF2; PPP1R12A; TIMP3; TWIST2; FLNC

Protein Function

MRAS has several biochemical functions, for example, GTP binding, GTP-dependent protein binding, GTPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MRAS itself. We selected most functions MRAS had, and list some proteins which have the same functions with MRAS. You can find most of the proteins on our site.
Function
Related Protein
Function GTP binding
Related Protein GBP5; GIMAP6; RHOGC; GPN1; MXB; AGAP2; ARFRP1; RHOUA; SRPRB; SEPT10
Function GTP-dependent protein binding
Related Protein PARD6A; AP1G1; AP3B1; RAB38; RAB5B; CDC42; MRAS; GCHFR; RASGRP4; ARFIP2
Function GTPase activity
Related Protein TUBA3E; MSTO1; ARHGDIB; RAB6A; RAB38; RRAGCB; RAB42; ARL1; GNAI1; RASD2
Function protein binding
Related Protein COPS7B; DOK6; ATP6V1B2; LGR6; GRIN1; AP2S1; WHSC2; FTSJ3; PIAS4; FAM40A

Interacting Protein

MRAS has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRAS here. Most of them are supplied by our site. Hope this information will be useful for your research of MRAS.
MLLT4; TCEB1; Rassf5; PLXNB1

MRAS Related Articles

Kassan, M; Galan, M; et al. Interleukin-10 Released by CD4(+)CD25(+) Natural Regulatory T Cells Improves Microvascular Endothelial Function Through Inhibition of NADPH Oxidase Activity in Hypertensive Mice. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 31:2534-U427(2011).
Novelli, G; Morabito, V; et al. Management of Sepsis During MARS Treatment in Acute on Chronic Liver Failure. TRANSPLANTATION PROCEEDINGS 43:1085-1090(2011).