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MTA1

  • Official Full Name

    metastasis associated 1

  • Overview

    MTA1 (metastasis associated gene 1) was identified in a differential screening of a cDNA library of metastatic and nonmetastatic adenocarcinoma cell lines (1), and was subsequently found to be an integral member of the nucleosome remodeling and deacetylat
  • Synonyms

    MTA1; metastasis associated 1; metastasis-associated protein MTA1; metastasis associated gene 1 protein;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • His|GST
  • Myc
  • DDK
  • MYC
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MTA1-2943H Recombinant Human MTA1 protein, MYC/DDK-tagged HEK293 Myc/DDK
Human MTA1-29503TH Recombinant Human MTA1, His-tagged E.coli His
Human MTA1-2455H Recombinant Human MTA1 protein, GST-tagged Wheat Germ GST
Human MTA1-2458H Recombinant Human MTA1 protein, GST-tagged Wheat Germ GST
Human MTA1-2459H Recombinant Human MTA1 protein, GST-tagged Wheat Germ GST
Human MTA1-4093HCL Recombinant Human MTA1 293 Cell Lysate HEK293 N/A
Human MTA1-1447H Recombinant Human MTA1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human MTA1-732HF Recombinant Full Length Human MTA1 Protein, GST-tagged In Vitro Cell Free System GST 255 amino acids
Human MTA1-5096H Recombinant Human MTA1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human MTA1-1137HFL Recombinant Full Length Human MTA1 Protein, C-Flag-tagged Mammalian cells Flag
Human MTA1-1447H-B Recombinant Human MTA1 Protein Pre-coupled Magnetic Beads HEK293
Mouse Mta1-2488M Recombinant Mouse Mta1 protein, His/GST-tagged E.coli His/GST Tyr6~Arg218
Mouse Mta1-580M Recombinant Mouse Mta1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rat MTA1-3801R Recombinant Rat MTA1 Protein Mammalian Cell His
Rat MTA1-3460R Recombinant Rat MTA1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat MTA1-3460R-B Recombinant Rat MTA1 Protein Pre-coupled Magnetic Beads HEK293
Chicken MTA1-2164C Recombinant Chicken MTA1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • MTA1 Related Articles

MTA1 involved in several pathways and played different roles in them. We selected most pathways MTA1 participated on our site, such as Chromatin modifying enzymes, Chromatin organization, Gene Expression, which may be useful for your reference. Also, other proteins which involved in the same pathway with MTA1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Chromatin modifying enzymesCHD4A;MORF4L2;SMARCD1;SUZ12B;DMAP1;ATXN7L3;SAP30;SMARCB1A;MTA3
Chromatin organizationCSRP2BP;ARID5B;PHF2;BRD1;SMARCB1;PAX3A;MSL2;ARID1A;KAT6A
Gene ExpressionZNF324;CBX3A;TACO1;ZNF234;CTGF;NR1I3;ZNF37A;ZNF549;ZKSCAN4
HDACs deacetylate histonesGATAD2A;BRMS1;MBD3;ARID4A;SAP18;HMG20B;MTA1;MBD3A;GATAD2AB
RNA Polymerase I Promoter ClearanceTAF1B;TAF1D;CHD4A;EFCAB11;TAF1C;RRN3;GATAD2AB;GATAD2B;MTA3
RNA Polymerase I TranscriptionGATAD2A;GATAD2B;MBD3B;CBX3A;UBTF;CBX3;CHD4;PTRF;MBD3A
RNA Polymerase I Transcription InitiationMBD3;CHD4A;GATAD2B;RRN3;UBTF;CHD4;GATAD2AB;MTA1;GATAD2A
RNA Polymerase I, RNA Polymerase III, and Mitochondrial TranscriptionBRF1;CBX3;TFB2M;CHD4A;MTA1;ZFP143;BRF2;GTF3AA;SNAPC1B

MTA1 has several biochemical functions, for example, RNA polymerase II repressing transcription factor binding, chromatin binding, core promoter binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MTA1 itself. We selected most functions MTA1 had, and list some proteins which have the same functions with MTA1. You can find most of the proteins on our site.

Function Related Protein
RNA polymerase II repressing transcription factor bindingBBS2;MKKS;GATA6;BBS1;MTA1;HDAC1;BBS4;TCERG1;BBS5
chromatin bindingUXT;WACA;SUZ12;NOC2L;SLC30A9;NKX2;ING2;NONO;EP300
core promoter bindingREST;CRY1;RBMX;SFPI1;SAFB;RB1;KLF4;CLOCK;MYBBP1A
core promoter sequence-specific DNA bindingZNF750;ZFP750;MEOX1;ESR1;MYOCD;PROX1;ZFP932;NR4A3;TRP53
enzyme bindingCAV1;TSPAN15;UGT1A6;HOXA9;TAL1;PIAS1;GRIN1;PTPLAD2;TSPAN10
protein bindingEXOC3;GPAA1;GOLPH3L;TPPP;KLHDC4;MPP2;IMP3;ACBD3;JAG2
transcription coactivator activityPMF1;ZEB1;TAF5L;ARID1A;CITED2;GTF2F1;HIF3A;ABRA;MMS19
transcription corepressor activityC1D;CTBP2;SMARCA4;LMCD1;SKOR1A;SSX2;HOMEZA;SSX3;HEYL
transcription factor activity, sequence-specific DNA bindingELF2B;NFKB1;PBX2;ETV5A;NFIXB;RXRA;NFYA;KDM5A;RB1
zinc ion bindingCA4A;ZCCHC6;LHX1A;CXXC1;RNF185;ZNF185;RNF39;MT1M;TRIM40

MTA1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MTA1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MTA1.

HDAC1; HDAC2; ESR1; MAGEA11; KRTAP10-8; RBBP4

Soler, DM; Ghosh, A; et al. A single element in the 3 ' UTR of the apical sodium-dependent bile acid transporter controls both stabilization and destabilization of mRNA. BIOCHEMICAL JOURNAL 462:547-553(2014).
Park, JO; Jung, CK; et al. Relationships between metastasis-associated protein (MTA) 1 and lymphatic metastasis in tonsil cancer. EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY 268:1329-1334(2011).
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