MTNR1B
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Official Full Name
melatonin receptor 1B
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Overview
This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin. -
Synonyms
MTNR1B; melatonin receptor 1B; melatonin receptor type 1B; mel1b receptor; melatonin receptor MEL1B; MT2; FGQTL2; MEL-1B-R;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Assay Kits
- Chicken
- Cynomolgus Monkey
- Homo sapiens (Human)
- Mus musculus (Mouse)
- Xenopus laevis (African clawed frog)
- E.coli
- E.coli expression system
- HEK293
- Mammalian Cell
- His
- His (Fc)
- Avi
- N/A
- N
- GST
- Involved Pathway
- Protein Function
- Interacting Protein
- MTNR1B Related Articles
MTNR1B involved in several pathways and played different roles in them. We selected most pathways MTNR1B participated on our site, such as Neuroactive ligand-receptor interaction, Circadian entrainment, which may be useful for your reference. Also, other proteins which involved in the same pathway with MTNR1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Neuroactive ligand-receptor interaction | GCGR;OPRM1;THRAA;CHRNB3;GLRA2;TAAR13D;GABRP;DRD4-RS;PRP2 |
| Circadian entrainment | GNGT1;GNG13;MAPK3;KCNJ9;Adcy4;PRKACA;CAMK2G;KCNJ5;PER3 |
MTNR1B has several biochemical functions, for example, G-protein coupled receptor activity, melatonin receptor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MTNR1B itself. We selected most functions MTNR1B had, and list some proteins which have the same functions with MTNR1B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| G-protein coupled receptor activity | GPR143;AGTR1B;TAS2R139;GPR22;MTNR1BA;TM2D1;CHRM5A;GPR15;OR115-6 |
| melatonin receptor activity | MTNR1B;MTNR1A;MTNR1C;MTNR1BB;GPR50;MTNR1AL;MTNR1AA;MTNR1BA |
| protein binding | RPS6KA4;DPYSL3;ZFP2;VAV3;DOCK4;ACTR3;TBC1D23;PPP3CB;ALDH3A1 |
MTNR1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MTNR1B here. Most of them are supplied by our site. Hope this information will be useful for your research of MTNR1B.
RGS20; MTNR1A; IRS4; PPM1G; GNAI2; GNAI3; HSPA5; FLNA; YWHAQ; CANX; PI4KA; COPA; GNB2; GNAI1; PDIA6; P4ha2; VPS35; GNB4
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