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NAGK

  • Official Full Name

    N-acetylglucosamine kinase

  • Overview

    N-acetylglucosamine kinase (NAGK; EC 2.7.1.59) converts endogenous N-acetylglucosamine (GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate. NAGK belongs to the group of N-acetylhexosamine kinases and is a prominent salvage enzyme of amino sugar metabolism in mammals.
  • Synonyms

    NAGK; N-acetylglucosamine kinase; N-acetyl-D-glucosamine kinase; EC 2.7.1.59; GlcNAc kinase; GNK; HSA242910; N acetylglucosamine kinase;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • C
  • His
  • His (Fc)
  • Avi
  • SUMO
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • T7
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human NAGK-2959H Recombinant Human NAGK protein, His-tagged E.coli His
Human NAGK-2946H Recombinant Human N-acetylglucosamine Kinase, T7-tagged E.coli T7
Human NAGK-146H Recombinant Human NAGK protein, T7-tagged E.coli T7
Human NAGK-428HCL Recombinant Human NAGK lysate HEK293 N/A
Human NAGK-183H Recombinant Human NAGK Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human NAGK-4973H Recombinant Human NAGK Protein (Ala2-Ser344), C-His tagged E.coli C-His Ala2-Ser344
Human NAGK-6146H Recombinant Human NAGK Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human NAGK-4896H Recombinant Human NAGK protein, His-SUMO-tagged E.coli His-SUMO 2-344aa
Mouse Nagk-4283M Recombinant Mouse Nagk Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat NAGK-3892R Recombinant Rat NAGK Protein Mammalian Cell His
Rat NAGK-3551R Recombinant Rat NAGK Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat NAGK-3551R-B Recombinant Rat NAGK Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • NAGK Related Articles
  • NAGK Related Research Area

NAGK involved in several pathways and played different roles in them. We selected most pathways NAGK participated on our site, such as Amino sugar and nucleotide sugar metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with NAGK were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Amino sugar and nucleotide sugar metabolismGPIA;CHIA.2;GMPPB;CHIA.4;CYB5RL;NANP;GPR19;CHIT1;FUK
Metabolic pathwaysGALNT6;POLR3K;CKBB;H6PD;SCP2;PDHA1;ATP5B;SGMS2;COQ7

NAGK has several biochemical functions, for example, ATP binding, N-acetylglucosamine kinase activity, N-acylmannosamine kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NAGK itself. We selected most functions NAGK had, and list some proteins which have the same functions with NAGK. You can find most of the proteins on our site.

Function Related Protein
ATP bindingMYLK4;PLK2;ILK;MAP3K1;FKBP4;YARS2;DDX17;PIM1;YARS
N-acetylglucosamine kinase activity
N-acylmannosamine kinase activityNAGK;GNE
protein bindingLRP5;FAM118A;CD5;TCF7;MAPK4;ATF5;KLHL18;TBC1D24;RAB2B

NAGK has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NAGK here. Most of them are supplied by our site. Hope this information will be useful for your research of NAGK.

b2r7w0_human; SDCBP; CDKN2C; MEOX1; REL; TCF12

Miura, Y; Sakurai, Y; et al. O-GlcNAc modification affects the ATM-mediated DNA damage response. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1820:1678-1685(2012).
Geng, F; Zhu, WJ; et al. Multiple post-translational modifications regulate E-cadherin transport during apoptosis. JOURNAL OF CELL SCIENCE 125:2615-2625(2012).
  • Q&As
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