naprt1
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  • Official Full Name
  • nicotinate phosphoribosyltransferase domain containing 1
  • Background
  • Nicotinic acid (NA; niacin) is converted by nicotinic acid phosphoribosyltransferase (NAPRT; EC 2.4.2.11) to NA mononucleotide (NaMN), which is then converted to NA adenine dinucleotide (NaAD), and finally to nicotinamide adenine dinucleotide (NAD), which serves as a coenzyme in cellular redox reactions and is an essential component of a variety of processes in cellular metabolism including response to stress (Hara et al., 2007).
  • Synonyms
  • NAPRT1; nicotinate phosphoribosyltransferase domain containing 1; nicotinate phosphoribosyltransferase; PP3856; FHIP; FHA HIT interacting protein; NAPRTase; Nicotinic acid phosphoribosyltransferase; FHA-HIT-interacting protein; nicotinate phosphoribosyltransferase domain-containing protein 1
Cat.#:NAPRT1-10426MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse NAPRT1 Protein
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Cat.#:NAPRT1-3902RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat NAPRT1 Protein
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Cat.#:NAPRT1-7104CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken NAPRT1
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Cat.#:NAPRT1-1165HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human NAPRT1 cell lysate
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Involved Pathway

NAPRT1 involved in several pathways and played different roles in them. We selected most pathways NAPRT1 participated on our site, such as Nicotinate and nicotinamide metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with NAPRT1 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Nicotinate and nicotinamide metabolism
NMRK2; AOX3; NT5M; NT5C3A; QPRT; NT5C; MIBP2; NMNAT1; ITGB1BP3; AOX3L1
Metabolic pathways
STT3B; PNLIPRP1; PDXKA; MVK; UAP1L1; ADH1B; UROD; CRYL1; PIGX; AKR1C3

Protein Function

NAPRT1 has several biochemical functions, for example, ligase activity, nicotinate phosphoribosyltransferase activity, nicotinate-nucleotide diphosphorylase (carboxylating) activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NAPRT1 itself. We selected most functions NAPRT1 had, and list some proteins which have the same functions with NAPRT1. You can find most of the proteins on our site.
Function
Related Protein
Function ligase activity
Related Protein UBE2NB; DTX4; CMTM2A; TRIM11; WWP2; RNF19A; RNF31; SHRPRBCK1R; ZNRF1; TRIP12
Function nicotinate phosphoribosyltransferase activity
Related Protein NAPRT; KCNG4; NAPRT1
Function nicotinate-nucleotide diphosphorylase (carboxylating) activity
Related Protein NAPRT1; QPRT; NAMPT; KCNG4; NAPRT; NAMPTB
Function protein binding
Related Protein CRABP2; SKP2; NUP37; SPSB3; MINK1; CCDC110; GOLGA7; RAMP2; NFKBIB; ROPN1L

Interacting Protein

NAPRT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NAPRT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NAPRT1.
RBPMS; GRAMD3; IGBP1