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NASP

  • Official Full Name

    nuclear autoantigenic sperm protein (histone-binding)

  • Overview

    This gene encodes a H1 histone binding protein that is involved in transporting histones into the nucleus of dividing cells. Multiple isoforms are encoded by transcript variants of this gene. The somatic form is expressed in all mitotic cells, is localized to the nucleus, and is coupled to the cell cycle. The testicular form is expressed in embryonic tissues, tumor cells, and the testis. In male germ cells, this protein is localized to the cytoplasm of primary spermatocytes, the nucleus of spermatids, and the periacrosomal region of mature spermatozoa.
  • Synonyms

    NASP; nuclear autoantigenic sperm protein (histone-binding); nuclear autoantigenic sperm protein; DKFZp547F162; FLB7527; FLJ31599; FLJ35510; MGC2297; MGC19722; MGC20372; PRO1999; 5033430J04Rik; AI131596; AI317140; D4Ertd767e; Epcs32; MGC93869; NASP_HUMAN; nuclear autoantigenic sperm protein (histone binding); RP23 233B9.9; histone H1-binding protein;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • Flag
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human NASP-3966HCL Recombinant Human NASP 293 Cell Lysate HEK293 N/A
Human NASP-585HFL Active Recombinant Full Length Human NASP Protein, C-Flag-tagged Mammalian cells Flag
Human NASP-1664H Recombinant Human NASP protein, His & T7-tagged E.coli His/T7 Met3~Asn223 (Accession # P49321)
Human NASP-1000H Recombinant Human NASP Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human NASP-1481H-B Recombinant Human NASP Protein Pre-coupled Magnetic Beads HEK293
Human NASP-1481H Recombinant Human NASP Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Nasp-4296M Recombinant Mouse Nasp Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat NASP-3905R Recombinant Rat NASP Protein Mammalian Cell His
Rat Nasp-7981R Recombinant Rat Nasp protein, His & T7-tagged E.coli His/T7 Thr3~Asp223 (Accession # Q66HD3)
Rat NASP-3564R Recombinant Rat NASP Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat NASP-3564R-B Recombinant Rat NASP Protein Pre-coupled Magnetic Beads HEK293
Zebrafish NASP-10170Z Recombinant Zebrafish NASP Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • NASP Related Articles

NASP involved in several pathways and played different roles in them. We selected most pathways NASP participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NASP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

NASP has several biochemical functions, for example, Hsp90 protein binding, histone binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NASP itself. We selected most functions NASP had, and list some proteins which have the same functions with NASP. You can find most of the proteins on our site.

Function Related Protein
Hsp90 protein bindingRPS3;ERN1;UNC45A;NPAS2;AHR;USP19;PPID;HIF1A;UNC45B
histone bindingPYGO2;HIST1H4K;HIST1H3E;HIST1H3I;NFKBIL2;ELP2;H2AFX;SPTY2D1;NPM1
protein bindingSERPINF2;TMED1;ELMO3;LMO1;PRCP;MAPK10;NRAP;RRAS2;CLCNKB
protein complex bindingATG101;UQCRC1;ERCC6;NDUFA9;RAP1A;TG;CDK2;MTHFR;CPS1

NASP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NASP here. Most of them are supplied by our site. Hope this information will be useful for your research of NASP.

HIST1H3D; TERF2IP; SGK1; BCAR3; TFE3; MCC; HLA-B; GABARAPL2; ARF6; IKBKE; FTSJ1; TRAF6; PTK2; TERF2; HIST2H3D; yvmA; ULK2; HDAC6

Ali-Fehmi, R; Chatterjee, M; et al. Analysis of the expression of human tumor antigens in ovarian cancer tissues. CANCER BIOMARKERS 6:33-48(2010).
Wang, M; Shi, JL; et al. The antibody against a nuclear autoantigenic sperm protein can result in reproductive failure. ASIAN JOURNAL OF ANDROLOGY 11:183-192(2009).
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