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NAV1

Official Full Name

neuron navigator 1
Overview

This gene belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. The exact function of this gene is not known, but it is thought to play a role in in neuronal development and regeneration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009]
Synonyms

NAV1; neuron navigator 1; POMFIL3; UNC53H1; STEERIN1; unc-53 homolog 1; neuron navigator-1; pore membrane and/or filament interacting like protein 3; pore membrane and/or filament-interacting-like protein 3;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse

Source

E.coli
HEK293
Mammalian Cell

Tag

GST
His
His (Fc)
Avi

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	NAV1-1198H	Recombinant Human NAV1, His-tagged	E.coli	His	1359-1530aa	$319 / 25ug
Human	NAV1-3690H	Recombinant Human NAV1 protein, GST-tagged	E.coli	GST	1359-1530 aa	$319 / 25ug
Human	NAV1-1028H	Recombinant Human NAV1 protein, His-tagged	E.coli	His	1362-1492aa	Inquiry
Human	NAV1-1029H	Recombinant Human NAV1 protein, His-tagged	E.coli	His	1098-1756aa	Inquiry
Mouse	NAV1-10443M	Recombinant Mouse NAV1 Protein	Mammalian Cell	His		Inquiry
Mouse	NAV1-5923M-B	Recombinant Mouse NAV1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	NAV1-5923M	Recombinant Mouse NAV1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry

Involved Pathway
Protein Function
Interacting Protein
NAV1 Related Articles

NAV1 involved in several pathways and played different roles in them. We selected most pathways NAV1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NAV1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

NAV1 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NAV1 itself. We selected most functions NAV1 had, and list some proteins which have the same functions with NAV1. You can find most of the proteins on our site.

Function	Related Protein
protein binding	ZHX1;KRTAP19-5;KLK4;IWS1;GDPD5;Raet1c;BTN3A1;UQCRC2;ADD1

NAV1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NAV1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NAV1.

TBC1D4; APC; MAPK1; YWHAB

Hien, YE; Montersino, A; et al. CK2 accumulation at the axon initial segment depends on sodium channel Nav1. FEBS LETTERS 588:3403-3408(2014).

Xia, L; Dou, NN; et al. Upregulation of Nav1.8 in Demyelinated Facial Nerves Might be Relevant to the Generation of Hemifacial Spasm. JOURNAL OF CRANIOFACIAL SURGERY 25:1334-1336(2014).