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NCKAP1

Official Full Name

NCK-associated protein 1
Overview

Nck-associated protein 1 is a protein that in humans is encoded by the NCKAP1 gene.
Synonyms

NCKAP1; NCK-associated protein 1; HEM2; Nap1; NAP125; NAP 1; p125Nap1; membrane-associated protein HEM-2; MGC8981; FLJ11291; KIAA0587;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Rat
Rhesus Macaque
Zebrafish

Source

E.coli
HEK293
Mammalian Cell

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	NCKAP1-1176H	Recombinant Human NCKAP1, GST-tagged	E.coli	GST	C-term-350aa	$319 / 25ug
Human	NCKAP1-3944HCL	Recombinant Human NCKAP1 293 Cell Lysate	HEK293	N/A		Inquiry
Rat	NCKAP1-3921R	Recombinant Rat NCKAP1 Protein	Mammalian Cell	His		Inquiry
Rat	NCKAP1-3579R	Recombinant Rat NCKAP1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	NCKAP1-3579R-B	Recombinant Rat NCKAP1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rhesus Macaque	NCKAP1-2957R	Recombinant Rhesus monkey NCKAP1 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	NCKAP1-2776R-B	Recombinant Rhesus Macaque NCKAP1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rhesus Macaque	NCKAP1-2776R	Recombinant Rhesus Macaque NCKAP1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Zebrafish	NCKAP1-7223Z	Recombinant Zebrafish NCKAP1	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

NCKAP1 involved in several pathways and played different roles in them. We selected most pathways NCKAP1 participated on our site, such as Diurnally regulated genes with circadian orthologs, E-cadherin signaling in the nascent adherens junction, ErbB1 downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with NCKAP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Diurnally regulated genes with circadian orthologs	G0S2;STBD1;RBPMS;CEBPB;QK;AZIN1;CRY2;CBX3;QKI
E-cadherin signaling in the nascent adherens junction	CTNND1;KLHL20;WASF2;ABI1;NCKAP1
ErbB1 downstream signaling	CHN2;ACTR3;ACTR2;NCKAP1;ABI1;MAP3K2;WASF2;EGR1;BAIAP2
Fcgamma receptor (FCGR) dependent phagocytosis	MYO9B;NCKIPSD;IgG3;ABI1;PPAPDC1B;ARPC1A;ACTR2B;MYO1C;NCKAP1
Immune System	TRIM46;TREML4;IRAK3;NA;CLEC5A;ASB18;BTR06;CFHL4;FBXO27
Innate Immune System	DEFA5;DEFB119;PPAPDC1A;CFD;CYLD;TXNIPA;CD300LB;BTR29;RIPK3
RAC1 signaling pathway	NOXO1;NCKAP1;BAIAP2;RACGAP1;ABI1;NOXA1;IQGAP3;ABI2
RHO GTPase Effectors	FMNL2;ACTR2B;BAIAP2;MIS12;SPDL1;SGOL2;RHPN2;ERCC6L;NCKIPSD

NCKAP1 has several biochemical functions, for example, contributes_to Rac GTPase binding, protein binding, protein complex binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NCKAP1 itself. We selected most functions NCKAP1 had, and list some proteins which have the same functions with NCKAP1. You can find most of the proteins on our site.

Function	Related Protein
contributes_to Rac GTPase binding	BRK1;ABI2;CYFIP1;NCKAP1;WASF1
protein binding	CCDC88A;ALDH1A2;TSHZ3;DEF6;DNAJC28;POLR1A;CTDNEP1;PRDM16;SDCBP2
protein complex binding	KAT6B;INS2;ULK1;CRHR1;PEX26;ANKRD32;Cel;PTPRF;CDK5RAP1

NCKAP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NCKAP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NCKAP1.

ABI1; YWHAB; ABI2; CYFIP1; GAS7